Brain Lower Grade Glioma_LGG_TCGA-S9-A6TU-01A-12R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

399 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-S9-A6TU-01A-12R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
AKAP1 A kinase (PRKA) anchor protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKNA AT-hook transcription factor
AMELX amelogenin, X-linked
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL5C ADP-ribosylation factor-like 5C
ARRB2 arrestin, beta 2
ARRDC2 arrestin domain containing 2
ATF5 activating transcription factor 5
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide
ATXN2L ataxin 2-like
ATXN7L2 ataxin 7-like 2
BANF2 barrier to autointegration factor 2
BANP BTG3 associated nuclear protein
BCL2L1 BCL2-like 1
BCL9L B-cell CLL/lymphoma 9-like
BIN1 bridging integrator 1
BRD1 bromodomain containing 1
BTG2 BTG family, member 2
BUD13 BUD13 homolog (S. cerevisiae)
C10ORF113 chromosome 10 open reading frame 113
C10ORF2 chromosome 10 open reading frame 2
C17ORF47 chromosome 17 open reading frame 47
C19ORF47 chromosome 19 open reading frame 47
C3ORF35 chromosome 3 open reading frame 35
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CASS4 Cas scaffolding protein family member 4
CCDC116 coiled-coil domain containing 116
CCDC84 coiled-coil domain containing 84
CCDC97 coiled-coil domain containing 97
CCL3 chemokine (C-C motif) ligand 3
CCNK cyclin K
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD3EAP CD3e molecule, epsilon associated protein
CDK11A cyclin-dependent kinase 11A
CDK8 cyclin-dependent kinase 8
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEP164 centrosomal protein 164kDa
CEP250 centrosomal protein 250kDa
CH25H cholesterol 25-hydroxylase
CIC capicua transcriptional repressor
CIZ1 CDKN1A interacting zinc finger protein 1
CLASRP CLK4-associating serine/arginine rich protein
CLCN1 chloride channel, voltage-sensitive 1
CLCN6 chloride channel, voltage-sensitive 6
CLK3 CDC-like kinase 3
CLLU1 chronic lymphocytic leukemia up-regulated 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COASY CoA synthase
CPB1 carboxypeptidase B1 (tissue)
CPSF3L cleavage and polyadenylation specific factor 3-like
CRTC2 CREB regulated transcription coactivator 2
CRYBA1 crystallin, beta A1
CSF1R colony stimulating factor 1 receptor
CSH2 chorionic somatomammotropin hormone 2
CSK c-src tyrosine kinase
CSNK1E casein kinase 1, epsilon
CST9L cystatin 9-like
CT45A3 cancer/testis antigen family 45, member A3
CTBP1 C-terminal binding protein 1
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head)
CTSG cathepsin G
CTU1 cytosolic thiouridylase subunit 1
CXORF21 chromosome X open reading frame 21
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene)
CYTH2 cytohesin 2
DAXX death-domain associated protein
DCST1 DC-STAMP domain containing 1
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DEFA6 defensin, alpha 6, Paneth cell-specific
DFNB31 deafness, autosomal recessive 31
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DLL1 delta-like 1 (Drosophila)
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DUOX1 dual oxidase 1
DUOXA1 dual oxidase maturation factor 1
DUSP27 dual specificity phosphatase 27 (putative)
DVL1 dishevelled segment polarity protein 1
E2F4 E2F transcription factor 4, p107/p130-binding
EDC4 enhancer of mRNA decapping 4
EDN1 endothelin 1
EEF2 eukaryotic translation elongation factor 2
EGR2 early growth response 2
EGR3 early growth response 3
ERCC1 excision repair cross-complementation group 1
ERF Ets2 repressor factor
EXOSC5 exosome component 5
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FAM118A family with sequence similarity 118, member A
FAM193A family with sequence similarity 193, member A
FAM53B family with sequence similarity 53, member B
FAM65A family with sequence similarity 65, member A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FBRS fibrosin
FBXO46 F-box protein 46
FGF17 fibroblast growth factor 17
FGFR4 fibroblast growth factor receptor 4
FLJ42393 uncharacterized LOC401105
FLYWCH1 FLYWCH-type zinc finger 1
FMO9P flavin containing monooxygenase 9 pseudogene
FOXR2 forkhead box R2
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAK cyclin G associated kinase
GALR3 galanin receptor 3
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GDF10 growth differentiation factor 10
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GH1 growth hormone 1
GIMAP5 GTPase, IMAP family member 5
GLTSCR2 glioma tumor suppressor candidate region gene 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNMT glycine N-methyltransferase
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPS2 G protein pathway suppressor 2
GPX3 glutathione peroxidase 3
GRAMD1A GRAM domain containing 1A
HDAC5 histone deacetylase 5
HES6 hes family bHLH transcription factor 6
HIC2 hypermethylated in cancer 2
HINFP histone H4 transcription factor
HMGN5 high mobility group nucleosome binding domain 5
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
IER3 immediate early response 3
IGFBP1 insulin-like growth factor binding protein 1
IL10RA interleukin 10 receptor, alpha
IL27 interleukin 27
IPO5 importin 5
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAT8 K(lysine) acetyltransferase 8
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM4E lysine (K)-specific demethylase 4E
KLF2 Kruppel-like factor 2
KLHL21 kelch-like family member 21
KLK14 kallikrein-related peptidase 14
KRTAP10-12 keratin associated protein 10-12
KRTAP5-1 keratin associated protein 5-1
LELP1 late cornified envelope-like proline-rich 1
LENEP lens epithelial protein
LENG8 leukocyte receptor cluster (LRC) member 8
LINC00032 long intergenic non-protein coding RNA 32
LINC00115 long intergenic non-protein coding RNA 115
LINC00310 long intergenic non-protein coding RNA 310
LINC00479 long intergenic non-protein coding RNA 479
LOC100134368 uncharacterized LOC100134368
LOC150776 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) pseudogene
LOC283332 uncharacterized LOC283332
LOC285768 uncharacterized LOC285768
LOC339568 uncharacterized LOC339568
LOC401010 nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene
LOC401127 WD repeat domain 5 pseudogene
LOC642929 general transcription factor II, i pseudogene
LOC643486
LOC647859 occludin pseudogene
LOC729609 uncharacterized LOC729609
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC47 leucine rich repeat containing 47
LSMEM2 leucine-rich single-pass membrane protein 2
LUC7L3 LUC7-like 3 (S. cerevisiae)
LY6G5B lymphocyte antigen 6 complex, locus G5B
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
LZTS2 leucine zipper, putative tumor suppressor 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD1 methyl-CpG binding domain protein 1
MED15 mediator complex subunit 15
MERTK MER proto-oncogene, tyrosine kinase
MGC2889 uncharacterized protein MGC2889
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MICALL1 MICAL-like 1
MKL1 megakaryoblastic leukemia (translocation) 1
MS4A10 membrane-spanning 4-domains, subfamily A, member 10
MTA1 metastasis associated 1
MTG2 mitochondrial ribosome-associated GTPase 2
MTMR9LP myotubularin related protein 9-like, pseudogene
MYBBP1A MYB binding protein (P160) 1a
MZF1 myeloid zinc finger 1
NBPF15 neuroblastoma breakpoint family, member 15
NCKAP5L NCK-associated protein 5-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELFA negative elongation factor complex member A
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFRKB nuclear factor related to kappaB binding protein
NKAP NFKB activating protein
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPIPB3 nuclear pore complex interacting protein family, member B3
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRTN neurturin
OR10G3 olfactory receptor, family 10, subfamily G, member 3
OR10G9 olfactory receptor, family 10, subfamily G, member 9
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR2B11 olfactory receptor, family 2, subfamily B, member 11
OR2C3 olfactory receptor, family 2, subfamily C, member 3
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR56A5 olfactory receptor, family 56, subfamily A, member 5
OSBPL7 oxysterol binding protein-like 7
OTUD1 OTU deubiquitinase 1
OVCH2 ovochymase 2 (gene/pseudogene)
PABPN1 poly(A) binding protein, nuclear 1
PANK4 pantothenate kinase 4
PATE4 prostate and testis expressed 4
PCED1A PC-esterase domain containing 1A
PCIF1 PDX1 C-terminal inhibiting factor 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD11 programmed cell death 11
PDCD2L programmed cell death 2-like
PDE8A phosphodiesterase 8A
PDGFB platelet-derived growth factor beta polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDXDC2P pyridoxal-dependent decarboxylase domain containing 2, pseudogene
PELP1 proline, glutamate and leucine rich protein 1
PFN1P2 profilin 1 pseudogene 2
PHRF1 PHD and ring finger domains 1
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCB2 phospholipase C, beta 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLXNB1 plexin B1
PODN podocan
POU5F2 POU domain class 5, transcription factor 2
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPARD peroxisome proliferator-activated receptor delta
PPIEL peptidylprolyl isomerase E-like pseudogene
PPP1R3E protein phosphatase 1, regulatory subunit 3E
PRAMEF4 PRAME family member 4
PRB4 proline-rich protein BstNI subfamily 4
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROM2 prominin 2
PRPF38B pre-mRNA processing factor 38B
PRR12 proline rich 12
PRR4 proline rich 4 (lacrimal)
PRSS41 protease, serine, 41
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTK6 protein tyrosine kinase 6
PTPN23 protein tyrosine phosphatase, non-receptor type 23
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD23A RAD23 homolog A (S. cerevisiae)
RBM20 RNA binding motif protein 20
RDH16 retinol dehydrogenase 16 (all-trans)
RGCC regulator of cell cycle
RGS11 regulator of G-protein signaling 11
RIPPLY1 ripply transcriptional repressor 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF183 ring finger protein 183
RNF214 ring finger protein 214
RPAP1 RNA polymerase II associated protein 1
RPL13A ribosomal protein L13a
RPL13AP20 ribosomal protein L13a pseudogene 20
RPS16 ribosomal protein S16
RPS5 ribosomal protein S5
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RSPO4 R-spondin 4
RTP2 receptor (chemosensory) transporter protein 2
RUVBL2 RuvB-like AAA ATPase 2
SAFB scaffold attachment factor B
SCAF1 SR-related CTD-associated factor 1
SDPR serum deprivation response
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEPT12 septin 12
SERHL serine hydrolase-like (pseudogene)
SFXN2 sideroflexin 2
SGK1 serum/glucocorticoid regulated kinase 1
SH2B1 SH2B adaptor protein 1
SIRT7 sirtuin 7
SKOR1 SKI family transcriptional corepressor 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMN1 survival of motor neuron 1, telomeric
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SNORA16B small nucleolar RNA, H/ACA box 16B
SNORA51 small nucleolar RNA, H/ACA box 51
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SP2 Sp2 transcription factor
SPACA6P sperm acrosome associated 6, pseudogene
SPRR2C small proline-rich protein 2C (pseudogene)
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SRRM1 serine/arginine repetitive matrix 1
SRSF4 serine/arginine-rich splicing factor 4
STH saitohin
STRN4 striatin, calmodulin binding protein 4
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SURF6 surfeit 6
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila)
SYMPK symplekin
SYVN1 synovial apoptosis inhibitor 1, synoviolin
SZT2 seizure threshold 2 homolog (mouse)
TAL1 T-cell acute lymphocytic leukemia 1
TAS2R20 taste receptor, type 2, member 20
TBATA thymus, brain and testes associated
TBC1D17 TBC1 domain family, member 17
TBC1D22A TBC1 domain family, member 22A
TBC1D26 TBC1 domain family, member 26
TBC1D3 TBC1 domain family, member 3
TBX2 T-box 2
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TCP10L t-complex 10-like
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOC5 THO complex 5
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNIP2 TNFAIP3 interacting protein 2
TPT1 tumor protein, translationally-controlled 1
TRIM28 tripartite motif containing 28
TRIM50 tripartite motif containing 50
TRIML2 tripartite motif family-like 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC2 tuberous sclerosis 2
TSPAN1 tetraspanin 1
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UNC13D unc-13 homolog D (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
USP35 ubiquitin specific peptidase 35
USP50 ubiquitin specific peptidase 50
UTS2 urotensin 2
VN1R4 vomeronasal 1 receptor 4
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WASH5P WAS protein family homolog 5 pseudogene
WASH7P WAS protein family homolog 7 pseudogene
WRAP73 WD repeat containing, antisense to TP73
WTIP Wilms tumor 1 interacting protein
WWC2-AS2 WWC2 antisense RNA 2
ZAN zonadhesin (gene/pseudogene)
ZBTB17 zinc finger and BTB domain containing 17
ZBTB45 zinc finger and BTB domain containing 45
ZC3H10 zinc finger CCCH-type containing 10
ZC3H18 zinc finger CCCH-type containing 18
ZC3H4 zinc finger CCCH-type containing 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYND15 zinc finger, MYND-type containing 15
ZNF202 zinc finger protein 202
ZNF213 zinc finger protein 213
ZNF274 zinc finger protein 274
ZNF321P zinc finger protein 321, pseudogene
ZNF324B zinc finger protein 324B
ZNF330 zinc finger protein 330
ZNF343 zinc finger protein 343
ZNF362 zinc finger protein 362
ZNF446 zinc finger protein 446
ZNF500 zinc finger protein 500
ZNF526 zinc finger protein 526
ZNF574 zinc finger protein 574
ZNF589 zinc finger protein 589
ZNF598 zinc finger protein 598
ZNF691 zinc finger protein 691
ZNF830 zinc finger protein 830
ZPR1 ZPR1 zinc finger
ZSCAN22 zinc finger and SCAN domain containing 22
ZSCAN9 zinc finger and SCAN domain containing 9

low expression

Symbol Name
AGGF1 angiogenic factor with G patch and FHA domains 1
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
COMMD10 COMM domain containing 10
COX7B cytochrome c oxidase subunit VIIb
ECHDC1 ethylmalonyl-CoA decarboxylase 1
GLO1 glyoxalase I
LCLAT1 lysocardiolipin acyltransferase 1
MED31 mediator complex subunit 31
ORC4 origin recognition complex, subunit 4
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
RAB1A RAB1A, member RAS oncogene family
SMIM15 small integral membrane protein 15
SRP9 signal recognition particle 9kDa
TMEM135 transmembrane protein 135
TRAPPC13 trafficking protein particle complex 13
TSN translin
TXNDC9 thioredoxin domain containing 9
UBE2N ubiquitin-conjugating enzyme E2N
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
WDR41 WD repeat domain 41