Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

299 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACPT acid phosphatase, testicular
ACTA1 actin, alpha 1, skeletal muscle
ACTN2 actinin, alpha 2
ADRA1B adrenoceptor alpha 1B
ADRBK1 adrenergic, beta, receptor kinase 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AMY2A amylase, alpha 2A (pancreatic)
ANKRD30A ankyrin repeat domain 30A
ANKRD37 ankyrin repeat domain 37
APOL5 apolipoprotein L, 5
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARL14 ADP-ribosylation factor-like 14
ARL5C ADP-ribosylation factor-like 5C
ASPDH aspartate dehydrogenase domain containing
ATOH7 atonal homolog 7 (Drosophila)
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATXN3L ataxin 3-like
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BEGAIN brain-enriched guanylate kinase-associated
BHLHE22 basic helix-loop-helix family, member e22
BPIFA1 BPI fold containing family A, member 1
BRSK1 BR serine/threonine kinase 1
BTBD2 BTB (POZ) domain containing 2
BTBD6 BTB (POZ) domain containing 6
C19ORF12 chromosome 19 open reading frame 12
C2ORF78 chromosome 2 open reading frame 78
C3ORF49 chromosome 3 open reading frame 49
C5ORF30 chromosome 5 open reading frame 30
C5ORF60 chromosome 5 open reading frame 60
C9ORF16 chromosome 9 open reading frame 16
CA11 carbonic anhydrase XI
CABP5 calcium binding protein 5
CALB2 calbindin 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CASKIN1 CASK interacting protein 1
CASP14 caspase 14, apoptosis-related cysteine peptidase
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCDC105 coiled-coil domain containing 105
CCDC83 coiled-coil domain containing 83
CDK16 cyclin-dependent kinase 16
CDKN2AIPNL CDKN2A interacting protein N-terminal like
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CELF4 CUGBP, Elav-like family member 4
CFC1B cripto, FRL-1, cryptic family 1B
CFHR4 complement factor H-related 4
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC4G C-type lectin domain family 4, member G
CPLX2 complexin 2
CPNE6 copine VI (neuronal)
CRTC1 CREB regulated transcription coactivator 1
CRYM crystallin, mu
CT45A4 cancer/testis antigen family 45, member A4
CT62 cancer/testis antigen 62
CTXN1 cortexin 1
CYCSP52 cytochrome c, somatic pseudogene 52
CYGB cytoglobin
CYP1B1-AS1 CYP1B1 antisense RNA 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DEFB4A defensin, beta 4A
DGKZ diacylglycerol kinase, zeta
DKFZP434J0226 uncharacterized LOC93429
DKK4 dickkopf WNT signaling pathway inhibitor 4
DLG4 discs, large homolog 4 (Drosophila)
DLGAP3 discs, large (Drosophila) homolog-associated protein 3
DMRTC1B DMRT-like family C1B
DMTN dematin actin binding protein
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DUSP8 dual specificity phosphatase 8
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EID2B EP300 interacting inhibitor of differentiation 2B
ELK1 ELK1, member of ETS oncogene family
EPCAM epithelial cell adhesion molecule
EPGN epithelial mitogen
EPN1 epsin 1
F2 coagulation factor II (thrombin)
FAM215A family with sequence similarity 215, member A (non-protein coding)
FAM217A family with sequence similarity 217, member A
FBXL16 F-box and leucine-rich repeat protein 16
FGF13 fibroblast growth factor 13
FOXD4L6 forkhead box D4-like 6
FOXQ1 forkhead box Q1
FTHL17 ferritin, heavy polypeptide-like 17
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GOLGA6L6 golgin A6 family-like 6
GP6 glycoprotein VI (platelet)
GPR83 G protein-coupled receptor 83
GRM3 glutamate receptor, metabotropic 3
GYPA glycophorin A (MNS blood group)
HAR1A highly accelerated region 1A (non-protein coding)
HAS1 hyaluronan synthase 1
ICAM5 intercellular adhesion molecule 5, telencephalin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IGHMBP2 immunoglobulin mu binding protein 2
IL34 interleukin 34
IL36G interleukin 36, gamma
IL36RN interleukin 36 receptor antagonist
IQCF1 IQ motif containing F1
IQCF6 IQ motif containing F6
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD17 potassium channel tetramerization domain containing 17
KDM8 lysine (K)-specific demethylase 8
KIF12 kinesin family member 12
KIFC2 kinesin family member C2
KLHL10 kelch-like family member 10
KLK5 kallikrein-related peptidase 5
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRT34 keratin 34, type I
KRT77 keratin 77, type II
KRT82 keratin 82, type II
KRTAP10-1 keratin associated protein 10-1
KRTAP7-1 keratin associated protein 7-1 (gene/pseudogene)
LAMP5 lysosomal-associated membrane protein family, member 5
LCN15 lipocalin 15
LIM2 lens intrinsic membrane protein 2, 19kDa
LIN7B lin-7 homolog B (C. elegans)
LINC00111 long intergenic non-protein coding RNA 111
LINC00207 long intergenic non-protein coding RNA 207
LINC00597 long intergenic non-protein coding RNA 597
LOC100133050 glucuronidase, beta pseudogene
LOC283070
LOC283731 uncharacterized LOC283731
LOC284578 uncharacterized LOC284578
LOC399815 chromosome 10 open reading frame 88 pseudogene
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRRC3B leucine rich repeat containing 3B
LRRC73 leucine rich repeat containing 73
LYPD5 LY6/PLAUR domain containing 5
LYPD6B LY6/PLAUR domain containing 6B
LYRM9 LYR motif containing 9
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAPK3 mitogen-activated protein kinase 3
MATK megakaryocyte-associated tyrosine kinase
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MROH2B maestro heat-like repeat family member 2B
MSANTD1 Myb/SANT-like DNA-binding domain containing 1
MSGN1 mesogenin 1
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYPOP Myb-related transcription factor, partner of profilin
NCDN neurochondrin
NCS1 neuronal calcium sensor 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NEURL1 neuralized E3 ubiquitin protein ligase 1
NKX6-3 NK6 homeobox 3
NPM2 nucleophosmin/nucleoplasmin 2
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
OAF OAF homolog (Drosophila)
OBP2B odorant binding protein 2B
OC90 otoconin 90
OLFM1 olfactomedin 1
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR10G4 olfactory receptor, family 10, subfamily G, member 4
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR52B6 olfactory receptor, family 52, subfamily B, member 6
OR8D4 olfactory receptor, family 8, subfamily D, member 4
OR8S1 olfactory receptor, family 8, subfamily S, member 1
OTOF otoferlin
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PALM paralemmin
PANX2 pannexin 2
PCDHB18P protocadherin beta 18 pseudogene
PCDHGA1 protocadherin gamma subfamily A, 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PGLYRP4 peptidoglycan recognition protein 4
PI3 peptidase inhibitor 3, skin-derived
PKD2L2 polycystic kidney disease 2-like 2
PKP3 plakophilin 3
PLD3 phospholipase D family, member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PNMAL1 paraneoplastic Ma antigen family-like 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB2 proline-rich protein BstNI subfamily 2
PRSS3 protease, serine, 3
PRSS30P protease, serine, 30, pseudogene
PSD pleckstrin and Sec7 domain containing
PWWP2B PWWP domain containing 2B
PYCRL pyrroline-5-carboxylate reductase-like
PYDC1 PYD (pyrin domain) containing 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB40C RAB40C, member RAS oncogene family
RAET1L retinoic acid early transcript 1L
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBMXL3 RNA binding motif protein, X-linked-like 3
RERG RAS-like, estrogen-regulated, growth inhibitor
RERGL RERG/RAS-like
RFPL2 ret finger protein-like 2
RHOV ras homolog family member V
RPL10L ribosomal protein L10-like
RPS15AP10 ribosomal protein S15a pseudogene 10
RTBDN retbindin
RTN4R reticulon 4 receptor
S100A14 S100 calcium binding protein A14
S100A7 S100 calcium binding protein A7
SCGB2A2 secretoglobin, family 2A, member 2
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEPT5 septin 5
SEPW1 selenoprotein W, 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGSM2 small G protein signaling modulator 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SIGLECL1 SIGLEC family like 1
SLC17A4 solute carrier family 17, member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SMPX small muscle protein, X-linked
SNCB synuclein, beta
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNORA72 small nucleolar RNA, H/ACA box 72
SNORA81 small nucleolar RNA, H/ACA box 81
SNORA9 small nucleolar RNA, H/ACA box 9
SOWAHA sosondowah ankyrin repeat domain family member A
SOX14 SRY (sex determining region Y)-box 14
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SYN1 synapsin I
SYN2 synapsin II
TAC3 tachykinin 3
TAS2R42 taste receptor, type 2, member 42
TECRL trans-2,3-enoyl-CoA reductase-like
TEX43 testis expressed 43
TFF1 trefoil factor 1
TGM6 transglutaminase 6
THOC3 THO complex 3
TMEM215 transmembrane protein 215
TNS4 tensin 4
TOLLIP toll interacting protein
TPD52L3 tumor protein D52-like 3
TPRX1 tetra-peptide repeat homeobox 1
TSPAN17 tetraspanin 17
TTC7B tetratricopeptide repeat domain 7B
TTC9B tetratricopeptide repeat domain 9B
TUBA8 tubulin, alpha 8
TUBBP5 tubulin, beta pseudogene 5
UBE2M ubiquitin-conjugating enzyme E2M
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
ULK1 unc-51 like autophagy activating kinase 1
UROS uroporphyrinogen III synthase
VCPKMT valosin containing protein lysine (K) methyltransferase
VWA7 von Willebrand factor A domain containing 7
WFDC5 WAP four-disulfide core domain 5
WIF1 WNT inhibitory factor 1
XAGE1E X antigen family, member 1E
YDJC YdjC homolog (bacterial)
YPEL1 yippee-like 1 (Drosophila)
ZBTB45 zinc finger and BTB domain containing 45
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZPBP zona pellucida binding protein
ZPBP2 zona pellucida binding protein 2

low expression

Symbol Name
ANKRD13A ankyrin repeat domain 13A
ATF7 activating transcription factor 7
BRAP BRCA1 associated protein
CBX5 chromobox homolog 5
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NKAP NFKB activating protein
PCBP2 poly(rC) binding protein 2
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
SCAF11 SR-related CTD-associated factor 11
SP1 Sp1 transcription factor
TMED6 transmembrane emp24 protein transport domain containing 6
TRAFD1 TRAF-type zinc finger domain containing 1