Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

418 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABHD8 abhydrolase domain containing 8
ABLIM2 actin binding LIM protein family, member 2
ACOT7 acyl-CoA thioesterase 7
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADPRHL1 ADP-ribosylhydrolase like 1
ADRB3 adrenoceptor beta 3
AGBL4 ATP/GTP binding protein-like 4
ALOXE3 arachidonate lipoxygenase 3
AMPH amphiphysin
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD34A ankyrin repeat domain 34A
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B
ASB2 ankyrin repeat and SOCS box containing 2
ASS1 argininosuccinate synthase 1
ATP13A2 ATPase type 13A2
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATXN7L3 ataxin 7-like 3
AVPI1 arginine vasopressin-induced 1
B3GNT1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAIAP2 BAI1-associated protein 2
BCYRN1 brain cytoplasmic RNA 1
BEGAIN brain-enriched guanylate kinase-associated
BFSP1 beaded filament structural protein 1, filensin
BTBD9 BTB (POZ) domain containing 9
C10ORF35 chromosome 10 open reading frame 35
C16ORF45 chromosome 16 open reading frame 45
C17ORF102 chromosome 17 open reading frame 102
C1ORF115 chromosome 1 open reading frame 115
C1ORF216 chromosome 1 open reading frame 216
C22ORF42 chromosome 22 open reading frame 42
C2CD2L C2CD2-like
C6ORF222 chromosome 6 open reading frame 222
C9ORF91 chromosome 9 open reading frame 91
CA11 carbonic anhydrase XI
CA7 carbonic anhydrase VII
CABP1 calcium binding protein 1
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALY calcyon neuron-specific vesicular protein
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMKV CaM kinase-like vesicle-associated
CARTPT CART prepropeptide
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBLN2 cerebellin 2 precursor
CBX7 chromobox homolog 7
CCBE1 collagen and calcium binding EGF domains 1
CCDC177 coiled-coil domain containing 177
CCDC27 coiled-coil domain containing 27
CCK cholecystokinin
CD99L2 CD99 molecule-like 2
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CEND1 cell cycle exit and neuronal differentiation 1
CFC1B cripto, FRL-1, cryptic family 1B
CHGA chromogranin A
CHN1 chimerin 1
CHRM1 cholinergic receptor, muscarinic 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLSTN3 calsyntenin 3
CNST consortin, connexin sorting protein
CPLX2 complexin 2
CRTC1 CREB regulated transcription coactivator 1
CTXN3 cortexin 3
CYMP chymosin pseudogene
CYP1B1-AS1 CYP1B1 antisense RNA 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DCLK3 doublecortin-like kinase 3
DDN dendrin
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DHDH dihydrodiol dehydrogenase (dimeric)
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DLG4 discs, large homolog 4 (Drosophila)
DMTN dematin actin binding protein
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNM1 dynamin 1
DOC2A double C2-like domains, alpha
DRGX dorsal root ganglia homeobox
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA5 ephrin-A5
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF4E1B eukaryotic translation initiation factor 4E family member 1B
EMX1 empty spiracles homeobox 1
EMX2OS EMX2 opposite strand/antisense RNA
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO2 enolase 2 (gamma, neuronal)
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPCAM epithelial cell adhesion molecule
EPHA10 EPH receptor A10
EPHB6 EPH receptor B6
EPHX4 epoxide hydrolase 4
EPN3 epsin 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVPL envoplakin
FADS6 fatty acid desaturase 6
FAIM2 Fas apoptotic inhibitory molecule 2
FAM163B family with sequence similarity 163, member B
FAM213B family with sequence similarity 213, member B
FAM224B family with sequence similarity 224, member B (non-protein coding)
FAM81A family with sequence similarity 81, member A
FAM9C family with sequence similarity 9, member C
FBXL16 F-box and leucine-rich repeat protein 16
FBXL18 F-box and leucine-rich repeat protein 18
FBXO27 F-box protein 27
FBXO44 F-box protein 44
FNDC9 fibronectin type III domain containing 9
FSTL4 follistatin-like 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFRA4 GDNF family receptor alpha 4
GIP gastric inhibitory polypeptide
GJB3 gap junction protein, beta 3, 31kDa
GJD4 gap junction protein, delta 4, 40.1kDa
GLP2R glucagon-like peptide 2 receptor
GLS2 glutaminase 2 (liver, mitochondrial)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR119 G protein-coupled receptor 119
GPR22 G protein-coupled receptor 22
GPR6 G protein-coupled receptor 6
GPR83 G protein-coupled receptor 83
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPRASP2 G protein-coupled receptor associated sorting protein 2
GRXCR1 glutaredoxin, cysteine rich 1
GSG1 germ cell associated 1
GSK3A glycogen synthase kinase 3 alpha
HAPLN4 hyaluronan and proteoglycan link protein 4
HAS1 hyaluronan synthase 1
HCG4 HLA complex group 4 (non-protein coding)
HCRTR2 hypocretin (orexin) receptor 2
HNF1A HNF1 homeobox A
HOOK1 hook microtubule-tethering protein 1
HPCAL1 hippocalcin-like 1
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
ICAM5 intercellular adhesion molecule 5, telencephalin
IFITM4P interferon induced transmembrane protein 4 pseudogene
IFNL3 interferon, lambda 3
IHH indian hedgehog
IPCEF1 interaction protein for cytohesin exchange factors 1
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITPKA inositol-trisphosphate 3-kinase A
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNIP4 Kv channel interacting protein 4
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNRG potassium channel regulator
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KCTD1 potassium channel tetramerization domain containing 1
KDF1 keratinocyte differentiation factor 1
KIAA0319 KIAA0319
KIAA1211L KIAA1211-like
KIAA1549L KIAA1549-like
KIF17 kinesin family member 17
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KRT28 keratin 28, type I
KRT3 keratin 3, type II
KRT82 keratin 82, type II
KRTAP10-4 keratin associated protein 10-4
LDB2 LIM domain binding 2
LMO4 LIM domain only 4
LOC100128554 uncharacterized LOC100128554
LOC283070
LOC340017 uncharacterized LOC340017
LOC344967 acyl-CoA thioesterase 7 pseudogene
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC650293 seven transmembrane helix receptor
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRRC73 leucine rich repeat containing 73
LRTM2 leucine-rich repeats and transmembrane domains 2
LSM11 LSM11, U7 small nuclear RNA associated
LURAP1L leucine rich adaptor protein 1-like
LY6H lymphocyte antigen 6 complex, locus H
LYPD6B LY6/PLAUR domain containing 6B
LYRM9 LYR motif containing 9
LYZL4 lysozyme-like 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEE1 melanoma antigen family E1
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAPK10 mitogen-activated protein kinase 10
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MATK megakaryocyte-associated tyrosine kinase
MC3R melanocortin 3 receptor
MDH1 malate dehydrogenase 1, NAD (soluble)
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIR600HG MIR600 host gene
MNT MAX network transcriptional repressor
MOAP1 modulator of apoptosis 1
MPO myeloperoxidase
MPPED1 metallophosphoesterase domain containing 1
MSANTD1 Myb/SANT-like DNA-binding domain containing 1
MT1IP metallothionein 1I, pseudogene
MTUS2 microtubule associated tumor suppressor candidate 2
MUM1L1 melanoma associated antigen (mutated) 1-like 1
MYF6 myogenic factor 6 (herculin)
MYPOP Myb-related transcription factor, partner of profilin
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAP1L2 nucleosome assembly protein 1-like 2
NAP1L5 nucleosome assembly protein 1-like 5
NCALD neurocalcin delta
NCDN neurochondrin
NCKIPSD NCK interacting protein with SH3 domain
NCOR1P1 nuclear receptor corepressor 1 pseudogene 1
NCS1 neuronal calcium sensor 1
NDEL1 nudE neurodevelopment protein 1-like 1
NEFL neurofilament, light polypeptide
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD2 neuronal differentiation 2
NGB neuroglobin
NGEF neuronal guanine nucleotide exchange factor
NICN1 nicolin 1
NISCH nischarin
NLRP2 NLR family, pyrin domain containing 2
NLRP7 NLR family, pyrin domain containing 7
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPM2 nucleophosmin/nucleoplasmin 2
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
NSF N-ethylmaleimide-sensitive factor
NUAK1 NUAK family, SNF1-like kinase, 1
NXPH2 neurexophilin 2
OLFM3 olfactomedin 3
OPN3 opsin 3
OPRL1 opiate receptor-like 1
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR52E6 olfactory receptor, family 52, subfamily E, member 6
OR5AU1 olfactory receptor, family 5, subfamily AU, member 1
OR8B2 olfactory receptor, family 8, subfamily B, member 2
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1
OVOL2 ovo-like zinc finger 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PANX2 pannexin 2
PCDH8 protocadherin 8
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE4C phosphodiesterase 4C, cAMP-specific
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PELI3 pellino E3 ubiquitin protein ligase family member 3
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PITPNM3 PITPNM family member 3
PITX3 paired-like homeodomain 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLSCR5 phospholipid scramblase family, member 5
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PNMA3 paraneoplastic Ma antigen 3
PNMA6A paraneoplastic Ma antigen family member 6A
PNMAL1 paraneoplastic Ma antigen family-like 1
PNMAL2 paraneoplastic Ma antigen family-like 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCZ protein kinase C, zeta
PRMT8 protein arginine methyltransferase 8
PRPF19 pre-mRNA processing factor 19
PRPH2 peripherin 2 (retinal degeneration, slow)
PRRT1 proline-rich transmembrane protein 1
PRRT2 proline-rich transmembrane protein 2
PRRT3 proline-rich transmembrane protein 3
PRSS3 protease, serine, 3
PSD pleckstrin and Sec7 domain containing
PSG3 pregnancy specific beta-1-glycoprotein 3
PTGDR2 prostaglandin D2 receptor 2
PTH2R parathyroid hormone 2 receptor
PTK2B protein tyrosine kinase 2 beta
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PYDC1 PYD (pyrin domain) containing 1
RAB3A RAB3A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAD21L1 RAD21-like 1 (S. pombe)
RASD2 RASD family, member 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBP4 retinol binding protein 4, plasma
RCVRN recoverin
REG1P regenerating islet-derived 1 pseudogene
RGS4 regulator of G-protein signaling 4
RGS7 regulator of G-protein signaling 7
RHEBL1 Ras homolog enriched in brain like 1
RHOV ras homolog family member V
RIMS3 regulating synaptic membrane exocytosis 3
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPRML reprimo-like
RSPO2 R-spondin 2
RTN2 reticulon 2
RUSC1 RUN and SH3 domain containing 1
SAMD14 sterile alpha motif domain containing 14
SBF1P1 SET binding factor 1 pseudogene 1
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEPT5 septin 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SERTM1 serine-rich and transmembrane domain containing 1
SH2D5 SH2 domain containing 5
SH3RF2 SH3 domain containing ring finger 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC45A1 solute carrier family 45, member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC7A4 solute carrier family 7, member 4
SMIM10L2A small integral membrane protein 10 like 2A
SMIM10L2B small integral membrane protein 10 like 2B
SMIM24 small integral membrane protein 24
SNCB synuclein, beta
SNORA80E small nucleolar RNA, H/ACA box 80E
SNPH syntaphilin
SNRPN small nuclear ribonucleoprotein polypeptide N
SOSTDC1 sclerostin domain containing 1
SOWAHA sosondowah ankyrin repeat domain family member A
SPATA31C1 SPATA31 subfamily C, member 1
SPATA31E1 SPATA31 subfamily E, member 1
SPIN2A spindlin family, member 2A
SPINK9 serine peptidase inhibitor, Kazal type 9
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPRYD3 SPRY domain containing 3
SSTR3 somatostatin receptor 3
SSTR4 somatostatin receptor 4
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
STAC2 SH3 and cysteine rich domain 2
STAT4 signal transducer and activator of transcription 4
STOML1 stomatin (EPB72)-like 1
STX1B syntaxin 1B
STXBP1 syntaxin binding protein 1
STYK1 serine/threonine/tyrosine kinase 1
SULT4A1 sulfotransferase family 4A, member 1
SYNGR3 synaptogyrin 3
TAGLN3 transgelin 3
TAS2R50 taste receptor, type 2, member 50
TBR1 T-box, brain, 1
TCEAL6 transcription elongation factor A (SII)-like 6
TCERG1L transcription elongation regulator 1-like
TCP10L2 t-complex 10-like 2
TESPA1 thymocyte expressed, positive selection associated 1
THEG theg spermatid protein
THY1 Thy-1 cell surface antigen
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM130 transmembrane protein 130
TMEM191A transmembrane protein 191A (pseudogene)
TMEM25 transmembrane protein 25
TMEM55B transmembrane protein 55B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNNT2 troponin T type 2 (cardiac)
TRIM51 tripartite motif-containing 51
TRNP1 TMF1-regulated nuclear protein 1
TSPYL1 TSPY-like 1
TSPYL4 TSPY-like 4
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA4A tubulin, alpha 4a
TUBA8 tubulin, alpha 8
UBE2MP1 ubiquitin-conjugating enzyme E2M pseudogene 1
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
ULK1 unc-51 like autophagy activating kinase 1
UNC5A unc-5 homolog A (C. elegans)
UTS2R urotensin 2 receptor
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VIP vasoactive intestinal peptide
VRTN vertebrae development associated
VSNL1 visinin-like 1
VSTM2L V-set and transmembrane domain containing 2 like
VSTM5 V-set and transmembrane domain containing 5
WASF1 WAS protein family, member 1
WBSCR17 Williams-Beuren syndrome chromosome region 17
WFDC10A WAP four-disulfide core domain 10A
WFDC13 WAP four-disulfide core domain 13
ZER1 zyg-11 related, cell cycle regulator
ZMAT4 zinc finger, matrin-type 4
ZNF215 zinc finger protein 215
ZNF365 zinc finger protein 365