Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

416 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABHD17B abhydrolase domain containing 17B
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACSM1 acyl-CoA synthetase medium-chain family member 1
ACSS2 acyl-CoA synthetase short-chain family member 2
ADAP1 ArfGAP with dual PH domains 1
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADIPOR2 adiponectin receptor 2
ADSSL1 adenylosuccinate synthase like 1
AFMID arylformamidase
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMPD3 adenosine monophosphate deaminase 3
ANAPC5 anaphase promoting complex subunit 5
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANLN anillin, actin binding protein
ANXA10 annexin A10
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP23 Rho GTPase activating protein 23
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARRDC2 arrestin domain containing 2
ASCL3 achaete-scute family bHLH transcription factor 3
ASPA aspartoacylase
ATG3 autophagy related 3
AVPI1 arginine vasopressin-induced 1
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BIN1 bridging integrator 1
BOK BCL2-related ovarian killer
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF90 chromosome 10 open reading frame 90
C12ORF56 chromosome 12 open reading frame 56
C12ORF76 chromosome 12 open reading frame 76
C16ORF70 chromosome 16 open reading frame 70
C19ORF45 chromosome 19 open reading frame 45
C1ORF64 chromosome 1 open reading frame 64
C1QTNF9B C1q and tumor necrosis factor related protein 9B
C21ORF91 chromosome 21 open reading frame 91
C2CD4D C2 calcium-dependent domain containing 4D
C5ORF52 chromosome 5 open reading frame 52
C9ORF139 chromosome 9 open reading frame 139
CAPN13 calpain 13
CAPN3 calpain 3, (p94)
CARD14 caspase recruitment domain family, member 14
CARNS1 carnosine synthase 1
CBR1 carbonyl reductase 1
CCDC54 coiled-coil domain containing 54
CCP110 centriolar coiled coil protein 110kDa
CD22 CD22 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK18 cyclin-dependent kinase 18
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDR2L cerebellar degeneration-related protein 2-like
CEMP1 cementum protein 1
CEP85 centrosomal protein 85kDa
CERCAM cerebral endothelial cell adhesion molecule
CERS2 ceramide synthase 2
CES4A carboxylesterase 4A
CES5A carboxylesterase 5A
CFL2 cofilin 2 (muscle)
CHADL chondroadherin-like
CHKA choline kinase alpha
CHN2 chimerin 2
CIB3 calcium and integrin binding family member 3
CIDEC cell death-inducing DFFA-like effector c
CLCA4 chloride channel accessory 4
CLCN7 chloride channel, voltage-sensitive 7
CLDN11 claudin 11
CLDND1 claudin domain containing 1
CLMN calmin (calponin-like, transmembrane)
CLRN2 clarin 2
CMA1 chymase 1, mast cell
CMTM5 CKLF-like MARVEL transmembrane domain containing 5
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTN2 contactin 2 (axonal)
COL4A5 collagen, type IV, alpha 5
COL9A2 collagen, type IX, alpha 2
CPB2 carboxypeptidase B2 (plasma)
CPOX coproporphyrinogen oxidase
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSDC2 cold shock domain containing C2, RNA binding
CSRP1 cysteine and glycine-rich protein 1
CYB5R2 cytochrome b5 reductase 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene
CYTH1 cytohesin 1
DAPK2 death-associated protein kinase 2
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DFNB31 deafness, autosomal recessive 31
DHCR24 24-dehydrocholesterol reductase
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNAH17 dynein, axonemal, heavy chain 17
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNTT DNA nucleotidylexotransferase
DOHH deoxyhypusine hydroxylase/monooxygenase
DYSF dysferlin
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL1 ELOVL fatty acid elongase 1
EML2 echinoderm microtubule associated protein like 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPCAM epithelial cell adhesion molecule
ERMN ermin, ERM-like protein
EVI2A ecotropic viral integration site 2A
EVI5L ecotropic viral integration site 5-like
FA2H fatty acid 2-hydroxylase
FAAH fatty acid amide hydrolase
FAM102A family with sequence similarity 102, member A
FAM107B family with sequence similarity 107, member B
FAM124A family with sequence similarity 124A
FAM131C family with sequence similarity 131, member C
FAM170A family with sequence similarity 170, member A
FAM178B family with sequence similarity 178, member B
FAM187B family with sequence similarity 187, member B
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
FAM221A family with sequence similarity 221, member A
FAM3A family with sequence similarity 3, member A
FAM53A family with sequence similarity 53, member A
FAM53B family with sequence similarity 53, member B
FAM58A family with sequence similarity 58, member A
FAM71A family with sequence similarity 71, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FCHO1 FCH domain only 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FFAR1 free fatty acid receptor 1
FGFR2 fibroblast growth factor receptor 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FMR1NB fragile X mental retardation 1 neighbor
FN3K fructosamine 3 kinase
FNBP1 formin binding protein 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FRMD4B FERM domain containing 4B
FXYD4 FXYD domain containing ion transport regulator 4
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GAMT guanidinoacetate N-methyltransferase
GDE1 glycerophosphodiester phosphodiesterase 1
GGT3P gamma-glutamyltransferase 3 pseudogene
GJB1 gap junction protein, beta 1, 32kDa
GJC2 gap junction protein, gamma 2, 47kDa
GLDN gliomedin
GLTP glycolipid transfer protein
GOLGA7 golgin A7
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPR137 G protein-coupled receptor 137
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR62 G protein-coupled receptor 62
GPRC5B G protein-coupled receptor, class C, group 5, member B
GREM1 gremlin 1, DAN family BMP antagonist
GRM3 glutamate receptor, metabotropic 3
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
H2BFWT H2B histone family, member W, testis-specific
HAPLN2 hyaluronan and proteoglycan link protein 2
HBS1L HBS1-like translational GTPase
HCCAT5 hepatocellular carcinoma associated transcript 5 (non-protein coding)
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDAC11 histone deacetylase 11
HFE2 hemochromatosis type 2 (juvenile)
HGC6.3 uncharacterized LOC100128124
HHATL hedgehog acyltransferase-like
HHIP hedgehog interacting protein
HID1 HID1 domain containing
HMGB4 high mobility group box 4
HOXD1 homeobox D1
HPN hepsin
HR hair growth associated
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPA2 heat shock 70kDa protein 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICOSLG inducible T-cell co-stimulator ligand
IFNW1 interferon, omega 1
IGSF8 immunoglobulin superfamily, member 8
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL17REL interleukin 17 receptor E-like
IL25 interleukin 25
ILVBL ilvB (bacterial acetolactate synthase)-like
INE2 inactivation escape 2 (non-protein coding)
INF2 inverted formin, FH2 and WH2 domain containing
IP6K3 inositol hexakisphosphate kinase 3
IPO13 importin 13
ITPK1 inositol-tetrakisphosphate 1-kinase
JAKMIP3 Janus kinase and microtubule interacting protein 3
JAM3 junctional adhesion molecule 3
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding)
KEL Kell blood group, metallo-endopeptidase
KIAA0408 KIAA0408
KIAA0930 KIAA0930
KIAA1598
KIF13B kinesin family member 13B
KIF25 kinesin family member 25
KIRREL3 kin of IRRE like 3 (Drosophila)
KLB klotho beta
KLHL25 kelch-like family member 25
KLK6 kallikrein-related peptidase 6
KRT71 keratin 71, type II
KRTAP5-11 keratin associated protein 5-11
KRTAP5-7 keratin associated protein 5-7
LARP6 La ribonucleoprotein domain family, member 6
LAYN layilin
LDB3 LIM domain binding 3
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LGI3 leucine-rich repeat LGI family, member 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00320 long intergenic non-protein coding RNA 320
LIPE lipase, hormone-sensitive
LOC151174 uncharacterized LOC151174
LOC644172 mitogen-activated protein kinase 8 interacting protein 1 pseudogene
LOC644936 actin, beta pseudogene
LPAR1 lysophosphatidic acid receptor 1
LRP2 low density lipoprotein receptor-related protein 2
LY6G6F lymphocyte antigen 6 complex, locus G6F
LZTS2 leucine zipper, putative tumor suppressor 2
MAG myelin associated glycoprotein
MAGEB3 melanoma antigen family B3
MAL mal, T-cell differentiation protein
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP6D1 MAP6 domain containing 1
MAP7 microtubule-associated protein 7
MBP myelin basic protein
MOBP myelin-associated oligodendrocyte basic protein
MOG myelin oligodendrocyte glycoprotein
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRI1 methylthioribose-1-phosphate isomerase 1
MRPL48 mitochondrial ribosomal protein L48
MTUS1 microtubule associated tumor suppressor 1
MVB12B multivesicular body subunit 12B
MVK mevalonate kinase
MYH14 myosin, heavy chain 14, non-muscle
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYO1D myosin ID
MYRF myelin regulatory factor
NACAD NAC alpha domain containing
NDRG1 N-myc downstream regulated 1
NEK3 NIMA-related kinase 3
NINJ2 ninjurin 2
NIPAL3 NIPA-like domain containing 3
NIPAL4 NIPA-like domain containing 4
NKAIN2 Na+/K+ transporting ATPase interacting 2
NKX6-2 NK6 homeobox 2
NOBOX NOBOX oogenesis homeobox
NPFFR2 neuropeptide FF receptor 2
NRIP2 nuclear receptor interacting protein 2
NT5DC1 5'-nucleotidase domain containing 1
NUTM2A NUT family member 2A
OLMALINC oligodendrocyte maturation-associated long intergenic non-coding RNA
OPALIN oligodendrocytic myelin paranodal and inner loop protein
OR10G8 olfactory receptor, family 10, subfamily G, member 8
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR2K2 olfactory receptor, family 2, subfamily K, member 2
OR4C3 olfactory receptor, family 4, subfamily C, member 3
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OR8B2 olfactory receptor, family 8, subfamily B, member 2
PACS2 phosphofurin acidic cluster sorting protein 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAOX polyamine oxidase (exo-N4-amino)
PAPL iron/zinc purple acid phosphatase-like protein
PAQR4 progestin and adipoQ receptor family member IV
PAQR6 progestin and adipoQ receptor family member VI
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX16 peroxisomal biogenesis factor 16
PFKL phosphofructokinase, liver
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLA2G16 phospholipase A2, group XVI
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLLP plasmolipin
PLP1 proteolipid protein 1
PMP22 peripheral myelin protein 22
POPDC3 popeye domain containing 3
POU1F1 POU class 1 homeobox 1
PPAP2C phosphatidic acid phosphatase type 2C
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PRCD progressive rod-cone degeneration
PRR18 proline rich 18
PRR34 proline rich 34
PSEN1 presenilin 1
PTDSS2 phosphatidylserine synthase 2
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPDC1 protein tyrosine phosphatase domain containing 1
PTPRH protein tyrosine phosphatase, receptor type, H
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PYY2 peptide YY, 2 (pseudogene)
QDPR quinoid dihydropteridine reductase
RAB40B RAB40B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RANGAP1 Ran GTPase activating protein 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASAL1 RAS protein activator like 1 (GAP1 like)
RBP7 retinol binding protein 7, cellular
RENBP renin binding protein
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RHOG ras homolog family member G
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF220 ring finger protein 220
RNH1 ribonuclease/angiogenin inhibitor 1
ROGDI rogdi homolog (Drosophila)
S1PR5 sphingosine-1-phosphate receptor 5
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPT12 septin 12
SEPT4 septin 4
SEPT8 septin 8
SEPW1 selenoprotein W, 1
SFTA2 surfactant associated 2
SFTPC surfactant protein C
SGK2 serum/glucocorticoid regulated kinase 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GL3 SH3-domain GRB2-like 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHB Src homology 2 domain containing adaptor protein B
SHROOM1 shroom family member 1
SLAIN1 SLAIN motif family, member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC45A3 solute carrier family 45, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SOST sclerostin
SP7 Sp7 transcription factor
SPATA19 spermatogenesis associated 19
SPEM1 spermatid maturation 1
SPNS2 spinster homolog 2 (Drosophila)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRCIN1 SRC kinase signaling inhibitor 1
ST18 suppression of tumorigenicity 18, zinc finger
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK31 serine/threonine kinase 31
STMN4 stathmin-like 4
STRA8 stimulated by retinoic acid 8
SUMO1P1 SUMO1 pseudogene 1
SUN2 Sad1 and UNC84 domain containing 2
SYNGR2 synaptogyrin 2
TARSL2 threonyl-tRNA synthetase-like 2
TBC1D10B TBC1 domain family, member 10B
TBCC tubulin folding cofactor C
TCEAL7 transcription elongation factor A (SII)-like 7
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TESK2 testis-specific kinase 2
TEX33 testis expressed 33
TF transferrin
TFEB transcription factor EB
THEMIS thymocyte selection associated
THSD1P1 thrombospondin, type I, domain containing 1 pseudogene 1
TIAF1 TGFB1-induced anti-apoptotic factor 1
TJAP1 tight junction associated protein 1 (peripheral)
TMC6 transmembrane channel-like 6
TMC7 transmembrane channel-like 7
TMCC2 transmembrane and coiled-coil domain family 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM125 transmembrane protein 125
TMEM141 transmembrane protein 141
TMEM144 transmembrane protein 144
TMEM151A transmembrane protein 151A
TMEM189 transmembrane protein 189
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM63A transmembrane protein 63A
TOPAZ1 testis and ovary specific PAZ domain containing 1
TP53INP2 tumor protein p53 inducible nuclear protein 2
TP53TG5 TP53 target 5
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TPPP tubulin polymerization promoting protein
TPRN taperin
TPSD1 tryptase delta 1
TRIM59 tripartite motif containing 59
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSIX TSIX transcript, XIST antisense RNA
TSPAN15 tetraspanin 15
TTYH2 tweety family member 2
TULP4 tubby like protein 4
TYMSOS TYMS opposite strand
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UCN3 urocortin 3
VSX2 visual system homeobox 2
VWA1 von Willebrand factor A domain containing 1
WBP2NL WBP2 N-terminal like
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC9 zinc finger, DHHC-type containing 9
ZFP57 ZFP57 zinc finger protein
ZFYVE19 zinc finger, FYVE domain containing 19
ZNF536 zinc finger protein 536

low expression

Symbol Name
BTBD18 BTB (POZ) domain containing 18
CELF1 CUGBP, Elav-like family member 1
CHMP3 charged multivesicular body protein 3
CRK v-crk avian sarcoma virus CT10 oncogene homolog
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
LRRC57 leucine rich repeat containing 57
NME6 NME/NM23 nucleoside diphosphate kinase 6
RBM8A RNA binding motif protein 8A
TMED6 transmembrane emp24 protein transport domain containing 6