Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

367 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABI3 ABI family, member 3
ACPP acid phosphatase, prostate
ADAM29 ADAM metallopeptidase domain 29
ADCY7 adenylate cyclase 7
ADGRE1 adhesion G protein-coupled receptor E1
ADM5 adrenomedullin 5 (putative)
AGMAT agmatine ureohydrolase (agmatinase)
AIF1 allograft inflammatory factor 1
AKNA AT-hook transcription factor
AKR1C4 aldo-keto reductase family 1, member C4
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ALOX5 arachidonate 5-lipoxygenase
AOAH acyloxyacyl hydrolase (neutrophil)
AOX2P aldehyde oxidase 2 pseudogene
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOC2 apolipoprotein C-II
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP27 Rho GTPase activating protein 27
ARHGAP4 Rho GTPase activating protein 4
ARHGAP9 Rho GTPase activating protein 9
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL11 ADP-ribosylation factor-like 11
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ASCL4 achaete-scute family bHLH transcription factor 4
ASIP agouti signaling protein
ATP13A5 ATPase type 13A5
ATP8B4 ATPase, class I, type 8B, member 4
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BCL2A1 BCL2-related protein A1
BIN2 bridging integrator 2
BLNK B-cell linker
BTK Bruton agammaglobulinemia tyrosine kinase
C12ORF77 chromosome 12 open reading frame 77
C16ORF54 chromosome 16 open reading frame 54
C16ORF90 chromosome 16 open reading frame 90
C19ORF38 chromosome 19 open reading frame 38
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C20ORF195 chromosome 20 open reading frame 195
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C8ORF58 chromosome 8 open reading frame 58
C9ORF66 chromosome 9 open reading frame 66
CARD9 caspase recruitment domain family, member 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCR1 chemokine (C-C motif) receptor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD14 CD14 molecule
CD180 CD180 molecule
CD226 CD226 molecule
CD300A CD300a molecule
CD4 CD4 molecule
CD53 CD53 molecule
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDK11A cyclin-dependent kinase 11A
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CELA1 chymotrypsin-like elastase family, member 1
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP7 charged multivesicular body protein 7
CLDN15 claudin 15
CLDN17 claudin 17
CLEC17A C-type lectin domain family 17, member A
CLIP2 CAP-GLY domain containing linker protein 2
CNTN3 contactin 3 (plasmacytoma associated)
COL6A4P2 collagen, type VI, alpha 4 pseudogene 2
COX8C cytochrome c oxidase subunit VIIIC
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTU1 cytosolic thiouridylase subunit 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYBA cytochrome b-245, alpha polypeptide
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYTH4 cytohesin 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNL drebrin-like
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DEFB115 defensin, beta 115
DENND1C DENN/MADD domain containing 1C
DENND3 DENN/MADD domain containing 3
DLL3 delta-like 3 (Drosophila)
DOCK2 dedicator of cytokinesis 2
DOK3 docking protein 3
DPYS dihydropyrimidinase
DUSP27 dual specificity phosphatase 27 (putative)
EBI3 Epstein-Barr virus induced 3
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EYS eyes shut homolog (Drosophila)
FAM110D family with sequence similarity 110, member D
FAM157A family with sequence similarity 157, member A
FAM160B2 family with sequence similarity 160, member B2
FAM177B family with sequence similarity 177, member B
FAM3B family with sequence similarity 3, member B
FAM47A family with sequence similarity 47, member A
FAM49B family with sequence similarity 49, member B
FAM92A1P2 family with sequence similarity 92, member A3
FCGBP Fc fragment of IgG binding protein
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FES FES proto-oncogene, tyrosine kinase
FGD2 FYVE, RhoGEF and PH domain containing 2
FKBP15 FK506 binding protein 15, 133kDa
FOXD4L1 forkhead box D4-like 1
FOXP2 forkhead box P2
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FUOM fucose mutarotase
FYB FYN binding protein
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
GIMAP1 GTPase, IMAP family member 1
GMIP GEM interacting protein
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GOLGA8G golgin A8 family, member G
GP9 glycoprotein IX (platelet)
GPR152 G protein-coupled receptor 152
GPR31 G protein-coupled receptor 31
GPR65 G protein-coupled receptor 65
GPR84 G protein-coupled receptor 84
GPSM3 G-protein signaling modulator 3
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2IP1 general transcription factor IIi pseudogene 1
HAMP hepcidin antimicrobial peptide
HCK HCK proto-oncogene, Src family tyrosine kinase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HGFAC HGF activator
HIST1H4J histone cluster 1, H4j
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H2BF histone cluster 2, H2bf
HIST2H3C histone cluster 2, H3c
HIST2H3D histone cluster 2, H3d
HORMAD1 HORMA domain containing 1
HPS3 Hermansky-Pudlak syndrome 3
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IGFLR1 IGF-like family receptor 1
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL17RA interleukin 17 receptor A
IL21R interleukin 21 receptor
IL4R interleukin 4 receptor
IL6R interleukin 6 receptor
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INTS1 integrator complex subunit 1
INTS8 integrator complex subunit 8
INTS9 integrator complex subunit 9
IRF2BPL interferon regulatory factor 2 binding protein-like
IRF5 interferon regulatory factor 5
IRF8 interferon regulatory factor 8
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK3 Janus kinase 3
JPX JPX transcript, XIST activator (non-protein coding)
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNK6 potassium channel, two pore domain subfamily K, member 6
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLHL33 kelch-like family member 33
KRTAP10-12 keratin associated protein 10-12
LACTB lactamase, beta
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAPTM5 lysosomal protein transmembrane 5
LAT2 linker for activation of T cells family, member 2
LGTN ligatin
LHB luteinizing hormone beta polypeptide
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINC00028 long intergenic non-protein coding RNA 28
LOC100133050 glucuronidase, beta pseudogene
LPAR5 lysophosphatidic acid receptor 5
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRG1 leucine-rich alpha-2-glycoprotein 1
LRMP lymphoid-restricted membrane protein
LRRC24 leucine rich repeat containing 24
LRRC25 leucine rich repeat containing 25
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRRN4 leucine rich repeat neuronal 4
LRWD1 leucine-rich repeats and WD repeat domain containing 1
LY86 lymphocyte antigen 86
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCPH1 microcephalin 1
MESTIT1 MEST intronic transcript 1, antisense RNA
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MIA2 melanoma inhibitory activity 2
MICALL1 MICAL-like 1
MILR1 mast cell immunoglobulin-like receptor 1
MLXIPL MLX interacting protein-like
MOCOS molybdenum cofactor sulfurase
MOGAT2 monoacylglycerol O-acyltransferase 2
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MPC2 mitochondrial pyruvate carrier 2
MPLKIP M-phase specific PLK1 interacting protein
MSLN mesothelin
MUC20 mucin 20, cell surface associated
MYBPC2 myosin binding protein C, fast type
MYO1F myosin IF
MYO1G myosin IG
NAGA N-acetylgalactosaminidase, alpha-
NAIP NLR family, apoptosis inhibitory protein
NAPRT nicotinate phosphoribosyltransferase
NAPSA napsin A aspartic peptidase
NAPSB napsin B aspartic peptidase, pseudogene
NCF4 neutrophil cytosolic factor 4, 40kDa
NCKAP1L NCK-associated protein 1-like
NEURL2 neuralized E3 ubiquitin protein ligase 2
NFAM1 NFAT activating protein with ITAM motif 1
NFRKB nuclear factor related to kappaB binding protein
NLRC4 NLR family, CARD domain containing 4
NLRP13 NLR family, pyrin domain containing 13
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUDT16P1 nudix (nucleoside diphosphate linked moiety X)-type motif 16 pseudogene 1
NUPL2 nucleoporin like 2
OR10G3 olfactory receptor, family 10, subfamily G, member 3
OR4C11 olfactory receptor, family 4, subfamily C, member 11
OR51G2 olfactory receptor, family 51, subfamily G, member 2
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR5T3 olfactory receptor, family 5, subfamily T, member 3
OSCAR osteoclast associated, immunoglobulin-like receptor
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PALD1 phosphatase domain containing, paladin 1
PARVG parvin, gamma
PEX6 peroxisomal biogenesis factor 6
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CD-AS1 PIK3CD antisense RNA 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA1A phospholipase A1 member A
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB2 phospholipase C, beta 2
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD4 phospholipase D family, member 4
PLXDC2 plexin domain containing 2
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
POU2F2 POU class 2 homeobox 2
PRAM1 PML-RARA regulated adaptor molecule 1
PRKG2 protein kinase, cGMP-dependent, type II
PTAFR platelet-activating factor receptor
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RASAL3 RAS protein activator like 3
RASGRP4 RAS guanyl releasing protein 4
RBMXL3 RNA binding motif protein, X-linked-like 3
RCC1 regulator of chromosome condensation 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
REPIN1 replication initiator 1
RGS18 regulator of G-protein signaling 18
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIMBP3C RIMS binding protein 3C
RIPK3 receptor-interacting serine-threonine kinase 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASET2 ribonuclease T2
RNF217 ring finger protein 217
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SAA3P serum amyloid A3 pseudogene
SAMD7 sterile alpha motif domain containing 7
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SASH3 SAM and SH3 domain containing 3
SCIN scinderin
SCRIB scribbled planar cell polarity protein
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3BP1 SH3-domain binding protein 1
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC5 sialic acid binding Ig-like lectin 5
SIGLEC9 sialic acid binding Ig-like lectin 9
SIPA1 signal-induced proliferation-associated 1
SIRPD signal-regulatory protein delta
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35E2 solute carrier family 35, member E2
SMAD6 SMAD family member 6
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNORA16B small nucleolar RNA, H/ACA box 16B
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA56 small nucleolar RNA, H/ACA box 56
SNX20 sorting nexin 20
SOWAHD sosondowah ankyrin repeat domain family member D
SPANXA2 SPANX family, member A2
SPATC1 spermatogenesis and centriole associated 1
SPI1 Spi-1 proto-oncogene
SPIDR scaffolding protein involved in DNA repair
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPP1 secreted phosphoprotein 1
SSH2 slingshot protein phosphatase 2
SSTR5 somatostatin receptor 5
SSX1 synovial sarcoma, X breakpoint 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAG3 stromal antigen 3
STXBP2 syntaxin binding protein 2
SUSD3 sushi domain containing 3
SYK spleen tyrosine kinase
TBPL2 TATA box binding protein like 2
TGFBR1 transforming growth factor, beta receptor 1
TIGD5 tigger transposable element derived 5
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMC8 transmembrane channel-like 8
TMEM106A transmembrane protein 106A
TMEM119 transmembrane protein 119
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TOPAZ1 testis and ovary specific PAZ domain containing 1
TOR4A torsin family 4, member A
TPRX1 tetra-peptide repeat homeobox 1
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRABD TraB domain containing
TRAF3IP3 TRAF3 interacting protein 3
TRIM42 tripartite motif containing 42
TSPO translocator protein (18kDa)
TTC36 tetratricopeptide repeat domain 36
TYMP thymidine phosphorylase
UBXN2B UBX domain protein 2B
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UFSP1 UFM1-specific peptidase 1 (non-functional)
UNC13D unc-13 homolog D (C. elegans)
UNC93A unc-93 homolog A (C. elegans)
USP42 ubiquitin specific peptidase 42
VAV1 vav 1 guanine nucleotide exchange factor
VSIG4 V-set and immunoglobulin domain containing 4
WAS Wiskott-Aldrich syndrome
WDFY4 WDFY family member 4
WDR60 WD repeat domain 60
WDR81 WD repeat domain 81
WWC2-AS2 WWC2 antisense RNA 2
ZDHHC19 zinc finger, DHHC-type containing 19
ZDHHC2 zinc finger, DHHC-type containing 2
ZFP92 ZFP92 zinc finger protein
ZNF280D zinc finger protein 280D
ZNF775 zinc finger protein 775
ZNF862 zinc finger protein 862

low expression

Symbol Name
COPS8 COP9 signalosome subunit 8
RAB11FIP3 RAB11 family interacting protein 3 (class II)