Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

390 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTBL2 actin, beta-like 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR1 activin A receptor, type I
ACVR1C activin A receptor, type IC
ACVRL1 activin A receptor type II-like 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRA2 adhesion G protein-coupled receptor A2
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADM5 adrenomedullin 5 (putative)
ADRA1B adrenoceptor alpha 1B
ADRA2C adrenoceptor alpha 2C
ADRB3 adrenoceptor beta 3
AFM afamin
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP5 A kinase (PRKA) anchor protein 5
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
ANXA3 annexin A3
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
AQP3 aquaporin 3 (Gill blood group)
AQP7 aquaporin 7
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARL15 ADP-ribosylation factor-like 15
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ASB17 ankyrin repeat and SOCS box containing 17
ASPN asporin
ASS1 argininosuccinate synthase 1
ATOH7 atonal homolog 7 (Drosophila)
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATXN10 ataxin 10
ATXN8OS ATXN8 opposite strand (non-protein coding)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BMX BMX non-receptor tyrosine kinase
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C19ORF33 chromosome 19 open reading frame 33
C1ORF185 chromosome 1 open reading frame 185
C1QTNF7 C1q and tumor necrosis factor related protein 7
C22ORF24 chromosome 22 open reading frame 24
C22ORF42 chromosome 22 open reading frame 42
C3ORF36 chromosome 3 open reading frame 36
C9ORF16 chromosome 9 open reading frame 16
CA11 carbonic anhydrase XI
CALB2 calbindin 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CASQ2 calsequestrin 2 (cardiac muscle)
CBLN1 cerebellin 1 precursor
CCBE1 collagen and calcium binding EGF domains 1
CCIN calicin
CCM2L cerebral cavernous malformation 2-like
CCNY cyclin Y
CD244 CD244 molecule, natural killer cell receptor 2B4
CDCP2 CUB domain containing protein 2
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH16 cadherin 16, KSP-cadherin
CDH22 cadherin 22, type 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CDHR2 cadherin-related family member 2
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CELA2B chymotrypsin-like elastase family, member 2B
CELF4 CUGBP, Elav-like family member 4
CHMP4C charged multivesicular body protein 4C
CLEC14A C-type lectin domain family 14, member A
CLEC1B C-type lectin domain family 1, member B
CLEC2L C-type lectin domain family 2, member L
CLEC4G C-type lectin domain family 4, member G
CLIC3 chloride intracellular channel 3
CLPS colipase, pancreatic
CLRN3 clarin 3
CMIP c-Maf inducing protein
CNN1 calponin 1, basic, smooth muscle
CNOT7 CCR4-NOT transcription complex, subunit 7
COL10A1 collagen, type X, alpha 1
CPLX2 complexin 2
CPNE6 copine VI (neuronal)
CRHR2 corticotropin releasing hormone receptor 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRYGC crystallin, gamma C
CRYGN crystallin, gamma N
CST2 cystatin SA
CST6 cystatin E/M
CT45A1 cancer/testis antigen family 45, member A1
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
DAZL deleted in azoospermia-like
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1
DCTN6 dynactin 6
DES desmin
DHH desert hedgehog
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJB3 DnaJ (Hsp40) homolog, subfamily B, member 3
DNAL4 dynein, axonemal, light chain 4
DOK6 docking protein 6
DSTN destrin (actin depolymerizing factor)
DUSP2 dual specificity phosphatase 2
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
EDN3 endothelin 3
EGFL8 EGF-like-domain, multiple 8
ELK1 ELK1, member of ETS oncogene family
EMCN endomucin
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPCAM epithelial cell adhesion molecule
EPGN epithelial mitogen
EPN3 epsin 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EVPLL envoplakin-like
EXOC6 exocyst complex component 6
FAM124B family with sequence similarity 124B
FAM26E family with sequence similarity 26, member E
FAM47A family with sequence similarity 47, member A
FBLN2 fibulin 2
FBLN5 fibulin 5
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FER1L6 fer-1-like family member 6
FGF18 fibroblast growth factor 18
FHL2 four and a half LIM domains 2
FHL5 four and a half LIM domains 5
FKBP1A FK506 binding protein 1A, 12kDa
FNDC9 fibronectin type III domain containing 9
FSTL4 follistatin-like 4
FTMT ferritin mitochondrial
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GDF2 growth differentiation factor 2
GH1 growth hormone 1
GHSR growth hormone secretagogue receptor
GIPC2 GIPC PDZ domain containing family, member 2
GJA5 gap junction protein, alpha 5, 40kDa
GLP2R glucagon-like peptide 2 receptor
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1
GOLGA6C golgin A6 family, member C
GOLGA6L1 golgin A6 family-like 1
GOLGA6L6 golgin A6 family-like 6
GOLGA8CP golgin A8 family, member C, pseudogene
GOLGA8DP golgin A8 family, member D, pseudogene
GOLGA8F golgin A8 family, member F
GPR101 G protein-coupled receptor 101
GPR68 G protein-coupled receptor 68
GPR83 G protein-coupled receptor 83
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM4 glutamate receptor, metabotropic 4
HDDC3 HD domain containing 3
HEBP2 heme binding protein 2
HEG1 heart development protein with EGF-like domains 1
HINT1 histidine triad nucleotide binding protein 1
HPCAL4 hippocalcin like 4
HSPA12B heat shock 70kD protein 12B
HYAL1 hyaluronoglucosaminidase 1
HYAL2 hyaluronoglucosaminidase 2
ICAM2 intercellular adhesion molecule 2
IDS iduronate 2-sulfatase
IL34 interleukin 34
IL3RA interleukin 3 receptor, alpha (low affinity)
IQCF6 IQ motif containing F6
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JAG2 jagged 2
KCMF1 potassium channel modulatory factor 1
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK17 potassium channel, two pore domain subfamily K, member 17
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KCTD17 potassium channel tetramerization domain containing 17
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1210 KIAA1210
KIAA1644 KIAA1644
KLHL1 kelch-like family member 1
KRT19 keratin 19, type I
KRT3 keratin 3, type II
KRT39 keratin 39, type I
KRT77 keratin 77, type II
KRTAP10-2 keratin associated protein 10-2
KRTAP9-9 keratin associated protein 9-9
LAMP5 lysosomal-associated membrane protein family, member 5
LCN15 lipocalin 15
LCN8 lipocalin 8
LINC00028 long intergenic non-protein coding RNA 28
LINC00207 long intergenic non-protein coding RNA 207
LOC100190940 uncharacterized LOC100190940
LOC283070
LOC284578 uncharacterized LOC284578
LOC728554 THO complex 3 pseudogene
LPA lipoprotein, Lp(a)
LRTM1 leucine-rich repeats and transmembrane domains 1
LYPD6B LY6/PLAUR domain containing 6B
MAGEB4 melanoma antigen family B4
MALL mal, T-cell differentiation protein-like
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MECR mitochondrial trans-2-enoyl-CoA reductase
MEF2A myocyte enhancer factor 2A
MEIS3 Meis homeobox 3
MGP matrix Gla protein
MMRN2 multimerin 2
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MPZL2 myelin protein zero-like 2
MPZL3 myelin protein zero-like 3
MT1IP metallothionein 1I, pseudogene
MUSTN1 musculoskeletal, embryonic nuclear protein 1
MYH11 myosin, heavy chain 11, smooth muscle
MYL10 myosin, light chain 10, regulatory
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL9 myosin, light chain 9, regulatory
MYLK2 myosin light chain kinase 2
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NCS1 neuronal calcium sensor 1
NDUFA4 NDUFA4, mitochondrial complex associated
NECAB2 N-terminal EF-hand calcium binding protein 2
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NET1 neuroepithelial cell transforming 1
NLRP5 NLR family, pyrin domain containing 5
NOS3 nitric oxide synthase 3 (endothelial cell)
NPAS1 neuronal PAS domain protein 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPTX2 neuronal pentraxin II
NPTXR neuronal pentraxin receptor
NR5A1 nuclear receptor subfamily 5, group A, member 1
OAF OAF homolog (Drosophila)
ODF1 outer dense fiber of sperm tails 1
OLFM1 olfactomedin 1
OR11H6 olfactory receptor, family 11, subfamily H, member 6
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR2A25 olfactory receptor, family 2, subfamily A, member 25
OR2A9P olfactory receptor, family 2, subfamily A, member 9 pseudogene
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR5V1 olfactory receptor, family 5, subfamily V, member 1
OTOF otoferlin
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR5 progestin and adipoQ receptor family member V
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE5A phosphodiesterase 5A, cGMP-specific
PDYN prodynorphin
PECAM1 platelet/endothelial cell adhesion molecule 1
PGK2 phosphoglycerate kinase 2
PITPNM3 PITPNM family member 3
PKP1 plakophilin 1
PLA1A phospholipase A1 member A
PLAC9 placenta-specific 9
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
PMEPA1 prostate transmembrane protein, androgen induced 1
PNPLA5 patatin-like phospholipase domain containing 5
PPA2 pyrophosphatase (inorganic) 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKCD protein kinase C, delta
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRM3 protamine 3
PROCR protein C receptor, endothelial
PRODH2 proline dehydrogenase (oxidase) 2
PRR19 proline rich 19
PRR27 proline rich 27
PRR5 proline rich 5 (renal)
PRSS3 protease, serine, 3
PTDSS1 phosphatidylserine synthase 1
PTGDR2 prostaglandin D2 receptor 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PYDC1 PYD (pyrin domain) containing 1
RAB12 RAB12, member RAS oncogene family
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RBPMS2 RNA binding protein with multiple splicing 2
RELN reelin
REM2 RAS (RAD and GEM)-like GTP binding 2
RERG RAS-like, estrogen-regulated, growth inhibitor
RERGL RERG/RAS-like
RESP18 regulated endocrine-specific protein 18
RGPD8 RANBP2-like and GRIP domain containing 8
RNF11 ring finger protein 11
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP53 ribosomal protein L23a pseudogene 53
RPLP0P2 ribosomal protein, large, P0 pseudogene 2
RPS4Y2 ribosomal protein S4, Y-linked 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RTN4RL1 reticulon 4 receptor-like 1
RTN4RL2 reticulon 4 receptor-like 2
RUNDC3B RUN domain containing 3B
SAMD3 sterile alpha motif domain containing 3
SCN5A sodium channel, voltage gated, type V alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEPW1 selenoprotein W, 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SFTA1P surfactant associated 1, pseudogene
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SH2D3C SH2 domain containing 3C
SH3RF2 SH3 domain containing ring finger 2
SHE Src homology 2 domain containing E
SLC12A8 solute carrier family 12, member 8
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC38A8 solute carrier family 38, member 8
SLC41A3 solute carrier family 41, member 3
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLIT3 slit homolog 3 (Drosophila)
SOAT2 sterol O-acyltransferase 2
SORBS2 sorbin and SH3 domain containing 2
SOWAHA sosondowah ankyrin repeat domain family member A
SPANXN3 SPANX family, member N3
SPATA31C1 SPATA31 subfamily C, member 1
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STAC2 SH3 and cysteine rich domain 2
STK24 serine/threonine kinase 24
STK32C serine/threonine kinase 32C
STXBP6 syntaxin binding protein 6 (amisyn)
SUMO3 small ubiquitin-like modifier 3
SV2C synaptic vesicle glycoprotein 2C
SYN2 synapsin II
SYNGR4 synaptogyrin 4
SYT7 synaptotagmin VII
TAAR1 trace amine associated receptor 1
TAC3 tachykinin 3
TACR2 tachykinin receptor 2
TAGLN transgelin
TAS2R8 taste receptor, type 2, member 8
TDGF1 teratocarcinoma-derived growth factor 1
TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3
TEK TEK tyrosine kinase, endothelial
TEX36 testis expressed 36
TEX37 testis expressed 37
TGM2 transglutaminase 2
TGM6 transglutaminase 6
THEG theg spermatid protein
THOC3 THO complex 3
THOC7 THO complex 7
TINCR tissue differentiation-inducing non-protein coding RNA
TMC1 transmembrane channel-like 1
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM200A transmembrane protein 200A
TMEM215 transmembrane protein 215
TMEM233 transmembrane protein 233
TMEM70 transmembrane protein 70
TMPRSS6 transmembrane protease, serine 6
TP53I11 tumor protein p53 inducible protein 11
TRIM43 tripartite motif containing 43
TRIM51 tripartite motif-containing 51
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TSPAN2 tetraspanin 2
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
TTTY8 testis-specific transcript, Y-linked 8 (non-protein coding)
TUBA4A tubulin, alpha 4a
TUBA8 tubulin, alpha 8
UBE2MP1 ubiquitin-conjugating enzyme E2M pseudogene 1
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10
ULK1 unc-51 like autophagy activating kinase 1
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
VDAC1 voltage-dependent anion channel 1
VEGFC vascular endothelial growth factor C
VN1R10P vomeronasal 1 receptor 10 pseudogene
VSTM2L V-set and transmembrane domain containing 2 like
WFDC12 WAP four-disulfide core domain 12
WIF1 WNT inhibitory factor 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZCCHC17 zinc finger, CCHC domain containing 17
ZNF702P zinc finger protein 702, pseudogene
ZP1 zona pellucida glycoprotein 1 (sperm receptor)