Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

294 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACE angiotensin I converting enzyme
ACER2 alkaline ceramidase 2
ACER3 alkaline ceramidase 3
ADAM12 ADAM metallopeptidase domain 12
ADGRL4 adhesion G protein-coupled receptor L4
AFAP1L1 actin filament associated protein 1-like 1
AKAP2 A kinase (PRKA) anchor protein 2
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ANGPT2 angiopoietin 2
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1
APLF aprataxin and PNKP like factor
APLN apelin
APOLD1 apolipoprotein L domain containing 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP12 Rho GTPase activating protein 12
ARL10 ADP-ribosylation factor-like 10
ASXL2 additional sex combs like transcriptional regulator 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAGE2 B melanoma antigen family, member 2
BBS10 Bardet-Biedl syndrome 10
BCL6B B-cell CLL/lymphoma 6, member B
C10ORF53 chromosome 10 open reading frame 53
C12ORF49 chromosome 12 open reading frame 49
C2ORF57 chromosome 2 open reading frame 57
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CAT catalase
CCNT1 cyclin T1
CD36 CD36 molecule (thrombospondin receptor)
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK12 cyclin-dependent kinase 12
CEP85L centrosomal protein 85kDa-like
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CKAP5 cytoskeleton associated protein 5
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CPT1A carnitine palmitoyltransferase 1A (liver)
CRACR2A calcium release activated channel regulator 2A
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRNN cornulin
CSAG1 chondrosarcoma associated gene 1
CTGF connective tissue growth factor
CTNND1 catenin (cadherin-associated protein), delta 1
CXORF38 chromosome X open reading frame 38
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
CYTH3 cytohesin 3
DACH2 dachshund family transcription factor 2
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DENND5A DENN/MADD domain containing 5A
DEPDC4 DEP domain containing 4
DGKH diacylglycerol kinase, eta
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DPEP3 dipeptidase 3
DSCR3 Down syndrome critical region 3
EDN1 endothelin 1
EEA1 early endosome antigen 1
EFTUD2 elongation factor Tu GTP binding domain containing 2
EGFEM1P EGF-like and EMI domain containing 1, pseudogene
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EP400 E1A binding protein p400
ERICH4 glutamate-rich 4
ESAM endothelial cell adhesion molecule
ESM1 endothelial cell-specific molecule 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVC Ellis van Creveld protein
FAM178A family with sequence similarity 178, member A
FAM26E family with sequence similarity 26, member E
FAM66C family with sequence similarity 66, member C
FANCB Fanconi anemia, complementation group B
FAR1 fatty acyl CoA reductase 1
FBXW8 F-box and WD repeat domain containing 8
FER fer (fps/fes related) tyrosine kinase
FLG filaggrin
FLJ42627 uncharacterized LOC645644
FOXL1 forkhead box L1
FSCB fibrous sheath CABYR binding protein
FSD2 fibronectin type III and SPRY domain containing 2
GLP1R glucagon-like peptide 1 receptor
GLYATL1 glycine-N-acyltransferase-like 1
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIP1 huntingtin interacting protein 1
HIPK3 homeodomain interacting protein kinase 3
HMBOX1 homeobox containing 1
HMCN1 hemicentin 1
HOOK3 hook microtubule-tethering protein 3
HSPG2 heparan sulfate proteoglycan 2
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IBSP integrin-binding sialoprotein
IDE insulin-degrading enzyme
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
ILDR2 immunoglobulin-like domain containing receptor 2
INS-IGF2 INS-IGF2 readthrough
INTS2 integrator complex subunit 2
INVS inversin
IPMK inositol polyphosphate multikinase
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
ITGA1 integrin, alpha 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JAZF1 JAZF zinc finger 1
KAT6A K(lysine) acetyltransferase 6A
KDR kinase insert domain receptor
KIAA0100 KIAA0100
KIAA1033 KIAA1033
KIRREL kin of IRRE like (Drosophila)
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
KRTAP4-11 keratin associated protein 4-11
KRTAP4-8 keratin associated protein 4-8
KTN1-AS1 KTN1 antisense RNA 1
LACE1 lactation elevated 1
LAMA4 laminin, alpha 4
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC3 laminin, gamma 3
LCE1A late cornified envelope 1A
LHFPL3 lipoma HMGIC fusion partner-like 3
LIMA1 LIM domain and actin binding 1
LIMS1 LIM and senescent cell antigen-like domains 1
LMBR1 limb development membrane protein 1
LOC284788 uncharacterized LOC284788
LOC441204 uncharacterized LOC441204
LOC650293 seven transmembrane helix receptor
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC3 leucine rich repeat containing 3
LRRC34 leucine rich repeat containing 34
LXN latexin
MAGEA12 melanoma antigen family A12
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MECOM MDS1 and EVI1 complex locus
MED1 mediator complex subunit 1
MED13 mediator complex subunit 13
MEP1A meprin A, alpha (PABA peptide hydrolase)
MMD2 monocyte to macrophage differentiation-associated 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP8 matrix metallopeptidase 8
MPHOSPH9 M-phase phosphoprotein 9
MPZL3 myelin protein zero-like 3
MTDH metadherin
MTNR1A melatonin receptor 1A
MXRA5 matrix-remodelling associated 5
MYCT1 myc target 1
MYO1B myosin IB
NAV1 neuron navigator 1
NBEAL1 neurobeachin-like 1
NCOA6 nuclear receptor coactivator 6
NCOR1 nuclear receptor corepressor 1
NCR1 natural cytotoxicity triggering receptor 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NF1 neurofibromin 1
NHLRC2 NHL repeat containing 2
NLRP10 NLR family, pyrin domain containing 10
NLRP14 NLR family, pyrin domain containing 14
NMUR1 neuromedin U receptor 1
NODAL nodal growth differentiation factor
NOX4 NADPH oxidase 4
NPAS3 neuronal PAS domain protein 3
NPSR1 neuropeptide S receptor 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRIP1 nuclear receptor interacting protein 1
NUP88 nucleoporin 88kDa
OR1N1 olfactory receptor, family 1, subfamily N, member 1
OR3A4P olfactory receptor, family 3, subfamily A, member 4 pseudogene
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
OR5C1 olfactory receptor, family 5, subfamily C, member 1
OR6V1 olfactory receptor, family 6, subfamily V, member 1
OSBPL8 oxysterol binding protein-like 8
OSM oncostatin M
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PANK3 pantothenate kinase 3
PCDH12 protocadherin 12
PCDH18 protocadherin 18
PCDHB10 protocadherin beta 10
PCDHB15 protocadherin beta 15
PCDHB2 protocadherin beta 2
PCDHB8 protocadherin beta 8
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGB4 protocadherin gamma subfamily B, 4
PCDHGC5 protocadherin gamma subfamily C, 5
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD8 PDZ domain containing 8
PEG3-AS1 PEG3 antisense RNA 1
PHF20 PHD finger protein 20
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PIWIL4 piwi-like RNA-mediated gene silencing 4
PLEK2 pleckstrin 2
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PNLIPRP3 pancreatic lipase-related protein 3
POMK protein-O-mannose kinase
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PPY pancreatic polypeptide
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRR16 proline rich 16
PRRC2C proline-rich coiled-coil 2C
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PXDNL peroxidasin-like
QSER1 glutamine and serine rich 1
RAB30 RAB30, member RAS oncogene family
RAI14 retinoic acid induced 14
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RASA3 RAS p21 protein activator 3
RBL1 retinoblastoma-like 1
RC3H2 ring finger and CCCH-type domains 2
REEP3 receptor accessory protein 3
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RNF152 ring finger protein 152
RP1 retinitis pigmentosa 1 (autosomal dominant)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RTTN rotatin
SAMD8 sterile alpha motif domain containing 8
SCAF11 SR-related CTD-associated factor 11
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC24A SEC24 family member A
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIK2 salt-inducible kinase 2
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC35D3 solute carrier family 35, member D3
SLC38A4 solute carrier family 38, member 4
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SLFN11 schlafen family member 11
SLFN5 schlafen family member 5
SLMO2 slowmo homolog 2 (Drosophila)
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SNTG1 syntrophin, gamma 1
SNX29 sorting nexin 29
SNX31 sorting nexin 31
SOGA1 suppressor of glucose, autophagy associated 1
SPATA13 spermatogenesis associated 13
ST14 suppression of tumorigenicity 14 (colon carcinoma)
SUSD6 sushi domain containing 6
SYN3 synapsin III
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TAOK1 TAO kinase 1
TBC1D28 TBC1 domain family, member 28
THSD7B thrombospondin, type I, domain containing 7B
TM4SF18 transmembrane 4 L six family member 18
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMSB15B thymosin beta 15B
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRAF3 TNF receptor-associated factor 3
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TRIP11 thyroid hormone receptor interactor 11
UBQLN3 ubiquilin 3
UEVLD UEV and lactate/malate dehyrogenase domains
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UHRF1BP1L UHRF1 binding protein 1-like
ULK2 unc-51 like autophagy activating kinase 2
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPREB1 pre-B lymphocyte 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VWF von Willebrand factor
WRN Werner syndrome, RecQ helicase-like
XKR4 XK, Kell blood group complex subunit-related family, member 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBTB16 zinc finger and BTB domain containing 16
ZBTB37 zinc finger and BTB domain containing 37
ZC3H12B zinc finger CCCH-type containing 12B
ZDHHC20 zinc finger, DHHC-type containing 20
ZIM2 zinc finger, imprinted 2
ZNF366 zinc finger protein 366
ZNF676 zinc finger protein 676
ZNF681 zinc finger protein 681
ZNF81 zinc finger protein 81

low expression

Symbol Name
GMEB2 glucocorticoid modulatory element binding protein 2
MRS2 MRS2 magnesium transporter
UBL4A ubiquitin-like 4A