Brain Lower Grade Glioma_LGG_TCGA-E1-5322-01A-01R-1470-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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371 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-E1-5322-01A-01R-1470-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABI1 abl-interactor 1
ACO1 aconitase 1, soluble
ADAM18 ADAM metallopeptidase domain 18
ADCK2 aarF domain containing kinase 2
ADGRG6 adhesion G protein-coupled receptor G6
ADGRL3 adhesion G protein-coupled receptor L3
AFAP1L2 actin filament associated protein 1-like 2
AKIRIN2 akirin 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANAPC13 anaphase promoting complex subunit 13
ANKRD13A ankyrin repeat domain 13A
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARMCX1 armadillo repeat containing, X-linked 1
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB13 ankyrin repeat and SOCS box containing 13
ASB7 ankyrin repeat and SOCS box containing 7
ASNSD1 asparagine synthetase domain containing 1
ATE1 arginyltransferase 1
ATF7IP activating transcription factor 7 interacting protein
ATP11AUN ATP11A upstream neighbor
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
BCDIN3D BCDIN3 domain containing
BICD2 bicaudal D homolog 2 (Drosophila)
BMP4 bone morphogenetic protein 4
BMP8B bone morphogenetic protein 8b
BMPR1A bone morphogenetic protein receptor, type IA
BST1 bone marrow stromal cell antigen 1
BTBD18 BTB (POZ) domain containing 18
C12ORF65 chromosome 12 open reading frame 65
C1ORF162 chromosome 1 open reading frame 162
C2ORF76 chromosome 2 open reading frame 76
C3AR1 complement component 3a receptor 1
C5ORF51 chromosome 5 open reading frame 51
C8ORF58 chromosome 8 open reading frame 58
C9ORF152 chromosome 9 open reading frame 152
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CBX5 chromobox homolog 5
CCDC178 coiled-coil domain containing 178
CCDC50 coiled-coil domain containing 50
CCNI cyclin I
CCNY cyclin Y
CD53 CD53 molecule
CDC123 cell division cycle 123
CDC26 cell division cycle 26
CDH18 cadherin 18, type 2
CDV3 CDV3 homolog (mouse)
CELF2 CUGBP, Elav-like family member 2
CFAP20 cilia and flagella associated protein 20
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CIAPIN1 cytokine induced apoptosis inhibitor 1
CNOT7 CCR4-NOT transcription complex, subunit 7
CNTN1 contactin 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COMMD9 COMM domain containing 9
COPZ1 coatomer protein complex, subunit zeta 1
CORO7 coronin 7
CPA6 carboxypeptidase A6
CPNE2 copine II
CPNE3 copine III
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTH cystathionine gamma-lyase
CTNND1 catenin (cadherin-associated protein), delta 1
CTNS cystinosin, lysosomal cystine transporter
CUL2 cullin 2
DCAF12 DDB1 and CUL4 associated factor 12
DCLRE1A DNA cross-link repair 1A
DCLRE1B DNA cross-link repair 1B
DCLRE1C DNA cross-link repair 1C
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEFB119 defensin, beta 119
DPPA5 developmental pluripotency associated 5
DTX4 deltex 4, E3 ubiquitin ligase
DUSP19 dual specificity phosphatase 19
EBI3 Epstein-Barr virus induced 3
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4A3 eukaryotic translation initiation factor 4A3
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF5AL1 eukaryotic translation initiation factor 5A-like 1
ELSPBP1 epididymal sperm binding protein 1
EPC1 enhancer of polycomb homolog 1 (Drosophila)
FAM222B family with sequence similarity 222, member B
FAM45A family with sequence similarity 45, member A
FAM96A family with sequence similarity 96, member A
FASTKD5 FAST kinase domains 5
FBXO18 F-box protein, helicase, 18
FBXO21 F-box protein 21
FBXO6 F-box protein 6
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCRLA Fc receptor-like A
FERMT1 fermitin family member 1
FGD3 FYVE, RhoGEF and PH domain containing 3
FIBIN fin bud initiation factor homolog (zebrafish)
FRMD4A FERM domain containing 4A
FSCN3 fascin actin-bundling protein 3, testicular
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
FYN FYN proto-oncogene, Src family tyrosine kinase
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9
GDAP2 ganglioside induced differentiation associated protein 2
GDI2 GDP dissociation inhibitor 2
GDNF glial cell derived neurotrophic factor
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLE1 GLE1 RNA export mediator
GLIPR2 GLI pathogenesis-related 2
GLUD1 glutamate dehydrogenase 1
GPR101 G protein-coupled receptor 101
GPR176 G protein-coupled receptor 176
GPR25 G protein-coupled receptor 25
GPR34 G protein-coupled receptor 34
GPR84 G protein-coupled receptor 84
GRID2 glutamate receptor, ionotropic, delta 2
GTF2B general transcription factor IIB
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF2I general transcription factor IIi
GUSBP1 glucuronidase, beta pseudogene 1
HCG4 HLA complex group 4 (non-protein coding)
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCRTR2 hypocretin (orexin) receptor 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HM13 histocompatibility (minor) 13
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA14 heat shock 70kDa protein 14
HSPA1L heat shock 70kDa protein 1-like
ICK intestinal cell (MAK-like) kinase
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFNGR1 interferon gamma receptor 1
IFNLR1 interferon, lambda receptor 1
IFT52 intraflagellar transport 52
IGFBPL1 insulin-like growth factor binding protein-like 1
IMPAD1 inositol monophosphatase domain containing 1
INHBC inhibin, beta C
JADE3 jade family PHD finger 3
JARID2 jumonji, AT rich interactive domain 2
KANSL2 KAT8 regulatory NSL complex subunit 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD5 potassium channel tetramerization domain containing 5
KIN Kin17 DNA and RNA binding protein
KLB klotho beta
LASP1 LIM and SH3 protein 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LIMA1 LIM domain and actin binding 1
LINC00028 long intergenic non-protein coding RNA 28
LINC00476 long intergenic non-protein coding RNA 476
LIX1L Lix1 homolog (chicken) like
LNP1 leukemia NUP98 fusion partner 1
LOC100128164 four and a half LIM domains 1 pseudogene
LOC100130264 uncharacterized LOC100130264
LOC90784 uncharacterized LOC90784
LPAR4 lysophosphatidic acid receptor 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRN3 leucine rich repeat neuronal 3
MAGEH1 melanoma antigen family H1
MCMBP minichromosome maintenance complex binding protein
MED20 mediator complex subunit 20
MEX3B mex-3 RNA binding family member B
MICU1 mitochondrial calcium uptake 1
MMP20 matrix metallopeptidase 20
MRGPRX1 MAS-related GPR, member X1
MRPL44 mitochondrial ribosomal protein L44
MRPS22 mitochondrial ribosomal protein S22
MSL2 male-specific lethal 2 homolog (Drosophila)
MSTN myostatin
MTPAP mitochondrial poly(A) polymerase
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NATD1 N-acetyltransferase domain containing 1
NDNL2 necdin-like 2
NEUROD1 neuronal differentiation 1
NKAPL NFKB activating protein-like
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NKX6-1 NK6 homeobox 1
NLRP13 NLR family, pyrin domain containing 13
NMB neuromedin B
NOMO1 NODAL modulator 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUPL2 nucleoporin like 2
OR10G4 olfactory receptor, family 10, subfamily G, member 4
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR6B1 olfactory receptor, family 6, subfamily B, member 1
OR6M1 olfactory receptor, family 6, subfamily M, member 1
OR7D4 olfactory receptor, family 7, subfamily D, member 4
OTC ornithine carbamoyltransferase
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PA2G4 proliferation-associated 2G4, 38kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PHF23 PHD finger protein 23
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PLD6 phospholipase D family, member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PM20D1 peptidase M20 domain containing 1
PNPLA1 patatin-like phospholipase domain containing 1
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKG2 protein kinase, cGMP-dependent, type II
PRR3 proline rich 3
PRTFDC1 phosphoribosyl transferase domain containing 1
RABGAP1 RAB GTPase activating protein 1
RAD51B RAD51 paralog B
RASGEF1B RasGEF domain family, member 1B
RBBP9 retinoblastoma binding protein 9
RBM15 RNA binding motif protein 15
RBM8A RNA binding motif protein 8A
RCC1 regulator of chromosome condensation 1
RCL1 RNA terminal phosphate cyclase-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIN2 Ras and Rab interactor 2
RIT1 Ras-like without CAAX 1
RNASE3 ribonuclease, RNase A family, 3
RNPEP arginyl aminopeptidase (aminopeptidase B)
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
SAP130 Sin3A-associated protein, 130kDa
SCARA3 scavenger receptor class A, member 3
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT4 sirtuin 4
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC35E4 solute carrier family 35, member E4
SLC38A9 solute carrier family 38, member 9
SLITRK6 SLIT and NTRK-like family, member 6
SLX4IP SLX4 interacting protein
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNAPIN SNAP-associated protein
SNCAIP synuclein, alpha interacting protein
SNW1 SNW domain containing 1
SOAT1 sterol O-acyltransferase 1
SOX15 SRY (sex determining region Y)-box 15
SP1 Sp1 transcription factor
SPON1 spondin 1, extracellular matrix protein
SPPL3 signal peptide peptidase like 3
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRSF3 serine/arginine-rich splicing factor 3
STRADB STE20-related kinase adaptor beta
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT6 synaptotagmin VI
SZRD1 SUZ RNA binding domain containing 1
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAS1R2 taste receptor, type 1, member 2
TCF12 transcription factor 12
TEX10 testis expressed 10
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLDC1 TBC/LysM-associated domain containing 1
TM2D2 TM2 domain containing 2
TM4SF20 transmembrane 4 L six family member 20
TMCC1 transmembrane and coiled-coil domain family 1
TMED6 transmembrane emp24 protein transport domain containing 6
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM164 transmembrane protein 164
TMEM52B transmembrane protein 52B
TMEM57 transmembrane protein 57
TMEM99 transmembrane protein 99
TMOD1 tropomodulin 1
TMOD4 tropomodulin 4 (muscle)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNIP2 TNFAIP3 interacting protein 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM40 tripartite motif containing 40
TRIM62 tripartite motif containing 62
TRIM68 tripartite motif containing 68
UBAP2 ubiquitin associated protein 2
UBAP2L ubiquitin associated protein 2-like
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
USP24 ubiquitin specific peptidase 24
USP39 ubiquitin specific peptidase 39
USP51 ubiquitin specific peptidase 51
USP6NL USP6 N-terminal like
VSIG4 V-set and immunoglobulin domain containing 4
WAC WW domain containing adaptor with coiled-coil
WDFY1 WD repeat and FYVE domain containing 1
YME1L1 YME1-like 1 ATPase
ZBTB33 zinc finger and BTB domain containing 33
ZDHHC16 zinc finger, DHHC-type containing 16
ZDHHC6 zinc finger, DHHC-type containing 6
ZFAT zinc finger and AT hook domain containing
ZMYM4 zinc finger, MYM-type 4
ZNF143 zinc finger protein 143
ZNF19 zinc finger protein 19
ZNF317 zinc finger protein 317
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF438 zinc finger protein 438
ZNF484 zinc finger protein 484
ZNF624 zinc finger protein 624
ZNF627 zinc finger protein 627
ZNF823 zinc finger protein 823

low expression

Symbol Name
ABHD5 abhydrolase domain containing 5
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
APEH acylaminoacyl-peptide hydrolase
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C15ORF40 chromosome 15 open reading frame 40
C3ORF18 chromosome 3 open reading frame 18
CCDC51 coiled-coil domain containing 51
CCDC66 coiled-coil domain containing 66
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ELP6 elongator acetyltransferase complex subunit 6
EPM2AIP1 EPM2A (laforin) interacting protein 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
GLT8D1 glycosyltransferase 8 domain containing 1
GOLGA4 golgin A4
HBS1L HBS1-like translational GTPase
HEMK1 HemK methyltransferase family member 1
IP6K1 inositol hexakisphosphate kinase 1
IP6K2 inositol hexakisphosphate kinase 2
LARP1 La ribonucleoprotein domain family, member 1
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LOC728024 chromosome X open reading frame 56 pseudogene
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MED7 mediator complex subunit 7
METTL6 methyltransferase like 6
MKRN2 makorin ring finger protein 2
MLH1 mutL homolog 1
MON1A MON1 secretory trafficking family member A
MRPL35 mitochondrial ribosomal protein L35
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEK4 NIMA-related kinase 4
NISCH nischarin
NUDCD2 NudC domain containing 2
NUP43 nucleoporin 43kDa
OGG1 8-oxoguanine DNA glycosylase
OXNAD1 oxidoreductase NAD-binding domain containing 1
PDCD6IP programmed cell death 6 interacting protein
PDE12 phosphodiesterase 12
PTPN23 protein tyrosine phosphatase, non-receptor type 23
QRICH1 glutamine-rich 1
RNF123 ring finger protein 123
RNF14 ring finger protein 14
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCAP SREBF chaperone
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SLC25A38 solute carrier family 25, member 38
SLMAP sarcolemma associated protein
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
TCAIM T cell activation inhibitor, mitochondrial
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TUSC2 tumor suppressor candidate 2
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UBP1 upstream binding protein 1 (LBP-1a)
USP19 ubiquitin specific peptidase 19
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
WDR6 WD repeat domain 6
XPC xeroderma pigmentosum, complementation group C
ZDHHC3 zinc finger, DHHC-type containing 3
ZNF197 zinc finger protein 197
ZNF346 zinc finger protein 346
ZNF589 zinc finger protein 589