Brain Lower Grade Glioma_LGG_TCGA-DU-7294-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

400 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-7294-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD17B abhydrolase domain containing 17B
ABHD2 abhydrolase domain containing 2
ABHD5 abhydrolase domain containing 5
ACACA acetyl-CoA carboxylase alpha
ACAT2 acetyl-CoA acetyltransferase 2
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AGPS alkylglycerone phosphate synthase
AKAP7 A kinase (PRKA) anchor protein 7
ALG9 ALG9, alpha-1,2-mannosyltransferase
ANKRD55 ankyrin repeat domain 55
ANKRD7 ankyrin repeat domain 7
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APH1B APH1B gamma secretase subunit
API5 apoptosis inhibitor 5
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARL4A ADP-ribosylation factor-like 4A
ARMC8 armadillo repeat containing 8
ARPIN actin-related protein 2/3 complex inhibitor
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASB1 ankyrin repeat and SOCS box containing 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ASCL3 achaete-scute family bHLH transcription factor 3
ASIC1 acid sensing (proton gated) ion channel 1
ATE1 arginyltransferase 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN7 ataxin 7
AWAT1 acyl-CoA wax alcohol acyltransferase 1
BARHL1 BarH-like homeobox 1
BCHE butyrylcholinesterase
BCLAF1 BCL2-associated transcription factor 1
BMP2 bone morphogenetic protein 2
BMPER BMP binding endothelial regulator
BMS1P5 BMS1 ribosome biogenesis factor pseudogene 5
BUB3 BUB3 mitotic checkpoint protein
C16ORF62 chromosome 16 open reading frame 62
C3ORF17 chromosome 3 open reading frame 17
C5ORF24 chromosome 5 open reading frame 24
CA10 carbonic anhydrase X
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAPN14 calpain 14
CAPRIN1 cell cycle associated protein 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCSER2 coiled-coil serine-rich protein 2
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CECR6 cat eye syndrome chromosome region, candidate 6
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CGGBP1 CGG triplet repeat binding protein 1
CHMP3 charged multivesicular body protein 3
CHURC1 churchill domain containing 1
CIRH1A cirrhosis, autosomal recessive 1A (cirhin)
CLVS2 clavesin 2
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CNIH1 cornichon family AMPA receptor auxiliary protein 1
COPS2 COP9 signalosome subunit 2
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CTNNA3 catenin (cadherin-associated protein), alpha 3
CUX2 cut-like homeobox 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DACH2 dachshund family transcription factor 2
DCTN4 dynactin 4 (p62)
DCTN5 dynactin 5 (p25)
DCX doublecortin
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DGKI diacylglycerol kinase, iota
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DIAPH2 diaphanous-related formin 2
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DROSHA drosha, ribonuclease type III
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DUSP19 dual specificity phosphatase 19
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EAPP E2F-associated phosphoprotein
ECD ecdysoneless homolog (Drosophila)
EDA2R ectodysplasin A2 receptor
EDC3 enhancer of mRNA decapping 3
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A1P9 eukaryotic translation elongation factor 1 alpha 1 pseudogene 9
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4B eukaryotic translation initiation factor 4B
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ELP2 elongator acetyltransferase complex subunit 2
EPN2 epsin 2
ETV1 ets variant 1
ETV5 ets variant 5
EXD2 exonuclease 3'-5' domain containing 2
EXOC2 exocyst complex component 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FAM13C family with sequence similarity 13, member C
FAM178A family with sequence similarity 178, member A
FAM192A family with sequence similarity 192, member A
FAM196A family with sequence similarity 196, member A
FAM217B family with sequence similarity 217, member B
FAM98B family with sequence similarity 98, member B
FBXO7 F-box protein 7
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FRY furry homolog (Drosophila)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLDC glycine dehydrogenase (decarboxylating)
GLP1R glucagon-like peptide 1 receptor
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRIP1 glutamate receptor interacting protein 1
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HACL1 2-hydroxyacyl-CoA lyase 1
HCG18 HLA complex group 18 (non-protein coding)
HDAC9 histone deacetylase 9
HDX highly divergent homeobox
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIP1 huntingtin interacting protein 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HSPA13 heat shock protein 70kDa family, member 13
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICE2 interactor of little elongation complex ELL subunit 2
IGBP1 immunoglobulin (CD79A) binding protein 1
IMPAD1 inositol monophosphatase domain containing 1
INIP INTS3 and NABP interacting protein
IPO7 importin 7
IQCF5 IQ motif containing F5
JPX JPX transcript, XIST activator (non-protein coding)
KARS lysyl-tRNA synthetase
KAT7 K(lysine) acetyltransferase 7
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNK2 potassium channel, two pore domain subfamily K, member 2
KDM1B lysine (K)-specific demethylase 1B
KDM6A lysine (K)-specific demethylase 6A
KIAA1586 KIAA1586
KIAA1644 KIAA1644
KIAA1715 KIAA1715
KIDINS220 kinase D-interacting substrate, 220kDa
KIF13A kinesin family member 13A
KIF21B kinesin family member 21B
KIF2A kinesin heavy chain member 2A
KIZ kizuna centrosomal protein
KLF12 Kruppel-like factor 12
KLHL9 kelch-like family member 9
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LARS leucyl-tRNA synthetase
LDOC1L leucine zipper, down-regulated in cancer 1-like
LEPROTL1 leptin receptor overlapping transcript-like 1
LETMD1 LETM1 domain containing 1
LHFPL3 lipoma HMGIC fusion partner-like 3
LIMA1 LIM domain and actin binding 1
LINC00574 long intergenic non-protein coding RNA 574
LOC100133050 glucuronidase, beta pseudogene
LOC441666 zinc finger protein 91 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC30 leucine rich repeat containing 30
LRRC58 leucine rich repeat containing 58
LRRN1 leucine rich repeat neuronal 1
LYRM7 LYR motif containing 7
MAGEH1 melanoma antigen family H1
MAML2 mastermind-like 2 (Drosophila)
MAP2 microtubule-associated protein 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MATR3 matrin 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
METTL10 methyltransferase like 10
MIP major intrinsic protein of lens fiber
MMD2 monocyte to macrophage differentiation-associated 2
MRPL3 mitochondrial ribosomal protein L3
MRPL30 mitochondrial ribosomal protein L30
MRPL45 mitochondrial ribosomal protein L45
MSH3 mutS homolog 3
MYO10 myosin X
NACA nascent polypeptide-associated complex alpha subunit
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NAP1L1 nucleosome assembly protein 1-like 1
NCKAP1 NCK-associated protein 1
NCOA3 nuclear receptor coactivator 3
NCOA4 nuclear receptor coactivator 4
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NHEJ1 nonhomologous end-joining factor 1
NONO non-POU domain containing, octamer-binding
NSL1 NSL1, MIS12 kinetochore complex component
NTN4 netrin 4
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP210 nucleoporin 210kDa
NUP35 nucleoporin 35kDa
NXPH1 neurexophilin 1
OLA1 Obg-like ATPase 1
OR5K1 olfactory receptor, family 5, subfamily K, member 1
ORC3 origin recognition complex, subunit 3
OSBPL8 oxysterol binding protein-like 8
OVCH2 ovochymase 2 (gene/pseudogene)
PA2G4 proliferation-associated 2G4, 38kDa
PCDH20 protocadherin 20
PCDHA10 protocadherin alpha 10
PCDHA6 protocadherin alpha 6
PCDHB17P protocadherin beta 17 pseudogene
PCDHB4 protocadherin beta 4
PCDHB6 protocadherin beta 6
PCDHGB6 protocadherin gamma subfamily B, 6
PCNX pecanex homolog (Drosophila)
PDCL phosducin-like
PDE4B phosphodiesterase 4B, cAMP-specific
PDZD2 PDZ domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PHAX phosphorylated adaptor for RNA export
PHF6 PHD finger protein 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PID1 phosphotyrosine interaction domain containing 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
POGLUT1 protein O-glucosyltransferase 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PRB3 proline-rich protein BstNI subfamily 3
PROSER1 proline and serine rich 1
PRPF8 pre-mRNA processing factor 8
PRRC1 proline-rich coiled-coil 1
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PTCD3 pentatricopeptide repeat domain 3
PTGFR prostaglandin F receptor (FP)
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PUS3 pseudouridylate synthase 3
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PWP1 PWP1 homolog (S. cerevisiae)
RAB14 RAB14, member RAS oncogene family
RAB3IP RAB3A interacting protein
RAPSN receptor-associated protein of the synapse
RBM22 RNA binding motif protein 22
RBM45 RNA binding motif protein 45
RBSN rabenosyn, RAB effector
REEP3 receptor accessory protein 3
RGMB repulsive guidance molecule family member b
RIOK2 RIO kinase 2
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNGTT RNA guanylyltransferase and 5'-phosphatase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL10 ribosomal protein L10
RPL17 ribosomal protein L17
RPL22L1 ribosomal protein L22-like 1
RPL3 ribosomal protein L3
RPL4 ribosomal protein L4
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPS23 ribosomal protein S23
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RSL24D1 ribosomal L24 domain containing 1
SCAMP1 secretory carrier membrane protein 1
SCEL sciellin
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN3B sodium channel, voltage gated, type III beta subunit
SEC23B Sec23 homolog B (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SH3BP4 SH3-domain binding protein 4
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLAIN1 SLAIN motif family, member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC35E3 solute carrier family 35, member E3
SLC38A1 solute carrier family 38, member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC39A9 solute carrier family 39, member 9
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SLMO2 slowmo homolog 2 (Drosophila)
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SNORA66 small nucleolar RNA, H/ACA box 66
SOS2 son of sevenless homolog 2 (Drosophila)
SOX6 SRY (sex determining region Y)-box 6
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SSTR2 somatostatin receptor 2
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STYX serine/threonine/tyrosine interacting protein
SUB1 SUB1 homolog (S. cerevisiae)
SULF2 sulfatase 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNRG synergin, gamma
SYT14 synaptotagmin XIV
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAS2R31 taste receptor, type 2, member 31
TAS2R40 taste receptor, type 2, member 40
TBC1D15 TBC1 domain family, member 15
TCEAL8 transcription elongation factor A (SII)-like 8
TCF12 transcription factor 12
TCF4 transcription factor 4
TFAM transcription factor A, mitochondrial
TFCP2 transcription factor CP2
TM9SF3 transmembrane 9 superfamily member 3
TMEM167A transmembrane protein 167A
TMEM168 transmembrane protein 168
TMEM169 transmembrane protein 169
TMEM30A transmembrane protein 30A
TMEM38B transmembrane protein 38B
TMEM87A transmembrane protein 87A
TMEM97 transmembrane protein 97
TNR tenascin R
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOX thymocyte selection-associated high mobility group box
TP53RK TP53 regulating kinase
TPP2 tripeptidyl peptidase II
TRIM13 tripartite motif containing 13
TRIM67 tripartite motif containing 67
TTC13 tetratricopeptide repeat domain 13
TUG1 taurine up-regulated 1 (non-protein coding)
TXNDC9 thioredoxin domain containing 9
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UNC79 unc-79 homolog (C. elegans)
UQCRC2 ubiquinol-cytochrome c reductase core protein II
USP51 ubiquitin specific peptidase 51
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VEPH1 ventricular zone expressed PH domain-containing 1
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VTA1 vesicle (multivesicular body) trafficking 1
VWA8 von Willebrand factor A domain containing 8
VWC2L von Willebrand factor C domain containing protein 2-like
WDFY1 WD repeat and FYVE domain containing 1
WDR12 WD repeat domain 12
WDR43 WD repeat domain 43
WDR44 WD repeat domain 44
WDR89 WD repeat domain 89
XKR7 XK, Kell blood group complex subunit-related family, member 7
XPO4 exportin 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZBTB16 zinc finger and BTB domain containing 16
ZBTB24 zinc finger and BTB domain containing 24
ZBTB6 zinc finger and BTB domain containing 6
ZBTB8B zinc finger and BTB domain containing 8B
ZC3H7A zinc finger CCCH-type containing 7A
ZCCHC24 zinc finger, CCHC domain containing 24
ZCCHC7 zinc finger, CCHC domain containing 7
ZDHHC21 zinc finger, DHHC-type containing 21
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP1 ZFP1 zinc finger protein
ZFR zinc finger RNA binding protein
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF24 zinc finger protein 24
ZNF254 zinc finger protein 254
ZNF277 zinc finger protein 277
ZNF287 zinc finger protein 287
ZNF510 zinc finger protein 510
ZNF519 zinc finger protein 519
ZNF608 zinc finger protein 608
ZNF675 zinc finger protein 675
ZNF681 zinc finger protein 681
ZNF717 zinc finger protein 717
ZNF727 zinc finger protein 727
ZNF737 zinc finger protein 737
ZNF85 zinc finger protein 85
ZNF93 zinc finger protein 93

low expression

Symbol Name
AMZ2P1 archaelysin family metallopeptidase 2 pseudogene 1
ASTE1 asteroid homolog 1 (Drosophila)
C19ORF47 chromosome 19 open reading frame 47
CTBP1 C-terminal binding protein 1
GAK cyclin G associated kinase
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
MAEA macrophage erythroblast attacher
NELFA negative elongation factor complex member A
ZDHHC8 zinc finger, DHHC-type containing 8