Brain Lower Grade Glioma_LGG_TCGA-DU-7019-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

339 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-7019-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABI1 abl-interactor 1
ACBD5 acyl-CoA binding domain containing 5
ACO1 aconitase 1, soluble
ACO2 aconitase 2, mitochondrial
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADGRF5 adhesion G protein-coupled receptor F5
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADI1 acireductone dioxygenase 1
AHCYL1 adenosylhomocysteinase-like 1
AHCYL2 adenosylhomocysteinase-like 2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA7 annexin A7
APMAP adipocyte plasma membrane associated protein
APOE apolipoprotein E
APOLD1 apolipoprotein L domain containing 1
ARSG arylsulfatase G
ASPH aspartate beta-hydroxylase
ATG4A autophagy related 4A, cysteine peptidase
ATL3 atlastin GTPase 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCAS3 breast carcinoma amplified sequence 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BTBD1 BTB (POZ) domain containing 1
C10ORF131 chromosome 10 open reading frame 131
C12ORF29 chromosome 12 open reading frame 29
C1ORF146 chromosome 1 open reading frame 146
C1QTNF7 C1q and tumor necrosis factor related protein 7
C2ORF69 chromosome 2 open reading frame 69
C2ORF78 chromosome 2 open reading frame 78
C5ORF51 chromosome 5 open reading frame 51
CA12 carbonic anhydrase XII
CALCRL calcitonin receptor-like
CD200R1L CD200 receptor 1-like
CD82 CD82 molecule
CD9 CD9 molecule
CDH7 cadherin 7, type 2
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CETN4P centrin EF-hand protein 4, pseudogene
CHMP5 charged multivesicular body protein 5
CHSY1 chondroitin sulfate synthase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CISD1 CDGSH iron sulfur domain 1
CIT citron rho-interacting serine/threonine kinase
CLASP1 cytoplasmic linker associated protein 1
CLC Charcot-Leyden crystal galectin
CLIC2 chloride intracellular channel 2
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNBD1 cyclic nucleotide binding domain containing 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COPS8 COP9 signalosome subunit 8
COQ10A coenzyme Q10 homolog A (S. cerevisiae)
COX18 COX18 cytochrome c oxidase assembly factor
CPNE3 copine III
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPT2 carnitine palmitoyltransferase 2
CROT carnitine O-octanoyltransferase
CS citrate synthase
CT45A1 cancer/testis antigen family 45, member A1
CT45A3 cancer/testis antigen family 45, member A3
CTH cystathionine gamma-lyase
CX3CL1 chemokine (C-X3-C motif) ligand 1
DARS aspartyl-tRNA synthetase
DAZAP2 DAZ associated protein 2
DBT dihydrolipoamide branched chain transacylase E2
DCAKD dephospho-CoA kinase domain containing
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DGKA diacylglycerol kinase, alpha 80kDa
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DLAT dihydrolipoamide S-acetyltransferase
DPH6 diphthamine biosynthesis 6
DYX1C1 dyslexia susceptibility 1 candidate 1
EBF1 early B-cell factor 1
ECI2 enoyl-CoA delta isomerase 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EDNRB endothelin receptor type B
EFNA3 ephrin-A3
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF3J eukaryotic translation initiation factor 3, subunit J
ELMO2 engulfment and cell motility 2
ELOVL7 ELOVL fatty acid elongase 7
EMC7 ER membrane protein complex subunit 7
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC4 excision repair cross-complementation group 4
ERO1LB ERO1-like beta (S. cerevisiae)
ETFA electron-transfer-flavoprotein, alpha polypeptide
F8 coagulation factor VIII, procoagulant component
FAM92A1P2 family with sequence similarity 92, member A3
FASTKD5 FAST kinase domains 5
FAT1 FAT atypical cadherin 1
FBXW12 F-box and WD repeat domain containing 12
FECH ferrochelatase
FERMT2 fermitin family member 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GADL1 glutamate decarboxylase-like 1
GALK2 galactokinase 2
GCDH glutaryl-CoA dehydrogenase
GHITM growth hormone inducible transmembrane protein
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GOLGA6C golgin A6 family, member C
GOLGA8EP golgin A8 family, member E, pseudogene
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPR137B G protein-coupled receptor 137B
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GSPT1 G1 to S phase transition 1
GTPBP4 GTP binding protein 4
HACD3 3-hydroxyacyl-CoA dehydratase 3
HADH hydroxyacyl-CoA dehydrogenase
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCG9 HLA complex group 9 (non-protein coding)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOXA13 homeobox A13
HPS5 Hermansky-Pudlak syndrome 5
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IDE insulin-degrading enzyme
ITM2A integral membrane protein 2A
IVD isovaleryl-CoA dehydrogenase
KCMF1 potassium channel modulatory factor 1
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCTD20 potassium channel tetramerization domain containing 20
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA0391 KIAA0391
KIAA1671 KIAA1671
KIF1BP KIF1 binding protein
KLHL23 kelch-like family member 23
KPNA3 karyopherin alpha 3 (importin alpha 4)
KRT12 keratin 12, type I
KRTAP9-8 keratin associated protein 9-8
L2HGDH L-2-hydroxyglutarate dehydrogenase
LACTB lactamase, beta
LARP4 La ribonucleoprotein domain family, member 4
LARP4B La ribonucleoprotein domain family, member 4B
LEPR leptin receptor
LIMS1 LIM and senescent cell antigen-like domains 1
LINC00052 long intergenic non-protein coding RNA 52
LIX1L Lix1 homolog (chicken) like
LONP2 lon peptidase 2, peroxisomal
LPL lipoprotein lipase
LRRC40 leucine rich repeat containing 40
LYPLAL1 lysophospholipase-like 1
LYRM2 LYR motif containing 2
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MANBA mannosidase, beta A, lysosomal
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCUR1 mitochondrial calcium uniporter regulator 1
METTL15 methyltransferase like 15
MFAP3 microfibrillar-associated protein 3
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MMRN2 multimerin 2
MOB4 MOB family member 4, phocein
MRPL19 mitochondrial ribosomal protein L19
MRPL3 mitochondrial ribosomal protein L3
MRPL39 mitochondrial ribosomal protein L39
MRPS22 mitochondrial ribosomal protein S22
MTCH2 mitochondrial carrier 2
MTO1 mitochondrial tRNA translation optimization 1
MUC7 mucin 7, secreted
MUT methylmalonyl CoA mutase
NARS asparaginyl-tRNA synthetase
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NEMF nuclear export mediator factor
NFS1 NFS1 cysteine desulfurase
NHSL2 NHS-like 2
NLGN4Y neuroligin 4, Y-linked
NLRP10 NLR family, pyrin domain containing 10
NMD3 NMD3 ribosome export adaptor
NMT2 N-myristoyltransferase 2
NMUR2 neuromedin U receptor 2
NNT nicotinamide nucleotide transhydrogenase
NOTCH2 notch 2
NOTCH2NL notch 2 N-terminal like
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRBF2 nuclear receptor binding factor 2
NRP2 neuropilin 2
OAF OAF homolog (Drosophila)
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OR4X2 olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)
OR6B1 olfactory receptor, family 6, subfamily B, member 1
OXCT1 3-oxoacid CoA transferase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PANK4 pantothenate kinase 4
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGA5 protocadherin gamma subfamily A, 5
PCYOX1 prenylcysteine oxidase 1
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHB pyruvate dehydrogenase (lipoamide) beta
PDHX pyruvate dehydrogenase complex, component X
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PEX19 peroxisomal biogenesis factor 19
PEX7 peroxisomal biogenesis factor 7
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKM phosphofructokinase, muscle
PGD phosphogluconate dehydrogenase
PGM3 phosphoglucomutase 3
PHYH phytanoyl-CoA 2-hydroxylase
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PLCD4 phospholipase C, delta 4
PNPLA1 patatin-like phospholipase domain containing 1
PNPO pyridoxamine 5'-phosphate oxidase
POC1B POC1 centriolar protein B
PPA2 pyrophosphatase (inorganic) 2
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP6C protein phosphatase 6, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRAMEF11 PRAME family member 11
PRAMEF14 PRAME family member 14
PRAMEF2 PRAME family member 2
PRAMEF8 PRAME family member 8
PRAMEF9 PRAME family member 9
PRDX3 peroxiredoxin 3
PTPRG protein tyrosine phosphatase, receptor type, G
PYGB phosphorylase, glycogen; brain
QKI QKI, KH domain containing, RNA binding
QRFPR pyroglutamylated RFamide peptide receptor
RAB12 RAB12, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RAG2 recombination activating gene 2
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RHOT1 ras homolog family member T1
RIT1 Ras-like without CAAX 1
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
SCG3 secretogranin III
SCO1 SCO1 cytochrome c oxidase assembly protein
SCP2 sterol carrier protein 2
SDCBP syndecan binding protein (syntenin)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDPR serum deprivation response
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SELE selectin E
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SFTPA2 surfactant protein A2
SH3BGRL SH3 domain binding glutamate-rich protein like
SHE Src homology 2 domain containing E
SIAE sialic acid acetylesterase
SLC16A6 solute carrier family 16, member 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMIM14 small integral membrane protein 14
SMIM21 small integral membrane protein 21
SMNDC1 survival motor neuron domain containing 1
SMR3A submaxillary gland androgen regulated protein 3A
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
SPARCL1 SPARC-like 1 (hevin)
SPIRE1 spire-type actin nucleation factor 1
STX12 syntaxin 12
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUGCT succinyl-CoA:glutarate-CoA transferase
SYT11 synaptotagmin XI
TAS1R2 taste receptor, type 1, member 2
TCP10L t-complex 10-like
TCTN3 tectonic family member 3
TECPR2 tectonin beta-propeller repeat containing 2
TEX36 testis expressed 36
TFB1M transcription factor B1, mitochondrial
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMP4 TIMP metallopeptidase inhibitor 4
TM4SF18 transmembrane 4 L six family member 18
TMED5 transmembrane emp24 protein transport domain containing 5
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM167B transmembrane protein 167B
TMLHE trimethyllysine hydroxylase, epsilon
TMPRSS12 transmembrane (C-terminal) protease, serine 12
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNPO2 transportin 2
TRAPPC3L trafficking protein particle complex 3-like
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TXNDC16 thioredoxin domain containing 16
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2
USP8 ubiquitin specific peptidase 8
UTRN utrophin
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
WBP1L WW domain binding protein 1-like
WDR12 WD repeat domain 12
YME1L1 YME1-like 1 ATPase
YOD1 YOD1 deubiquitinase
ZBTB33 zinc finger and BTB domain containing 33
ZBTB6 zinc finger and BTB domain containing 6
ZBTB7C zinc finger and BTB domain containing 7C
ZC3H14 zinc finger CCCH-type containing 14
ZFAND6 zinc finger, AN1-type domain 6
ZMYND11 zinc finger, MYND-type containing 11
ZNF330 zinc finger protein 330
ZNF366 zinc finger protein 366
ZNF442 zinc finger protein 442
ZNF770 zinc finger protein 770

low expression

Symbol Name
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
PBDC1 polysaccharide biosynthesis domain containing 1
UBXN6 UBX domain protein 6