Brain Lower Grade Glioma_LGG_TCGA-DU-7015-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

315 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-7015-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACSM5 acyl-CoA synthetase medium-chain family member 5
ACY3 aminoacylase 3
ADCY8 adenylate cyclase 8 (brain)
ADGRB1 adhesion G protein-coupled receptor B1
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
AGGF1 angiogenic factor with G patch and FHA domains 1
AGMAT agmatine ureohydrolase (agmatinase)
AGO2 argonaute RISC catalytic component 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ANGEL2 angel homolog 2 (Drosophila)
ANXA8 annexin A8
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARCN1 archain 1
ARHGAP5 Rho GTPase activating protein 5
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARL5A ADP-ribosylation factor-like 5A
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF6 activating transcription factor 6
ATP8B4 ATPase, class I, type 8B, member 4
BAGE2 B melanoma antigen family, member 2
BBX bobby sox homolog (Drosophila)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BLNK B-cell linker
BMP15 bone morphogenetic protein 15
BROX BRO1 domain and CAAX motif containing
C11ORF94 chromosome 11 open reading frame 94
C12ORF75 chromosome 12 open reading frame 75
C2ORF49 chromosome 2 open reading frame 49
C6ORF89 chromosome 6 open reading frame 89
C8ORF33 chromosome 8 open reading frame 33
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC25 coiled-coil domain containing 25
CDC5L cell division cycle 5-like
CDC73 cell division cycle 73
CDK15 cyclin-dependent kinase 15
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CELA1 chymotrypsin-like elastase family, member 1
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CMTR2 cap methyltransferase 2
CPED1 cadherin-like and PC-esterase domain containing 1
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CR1L complement component (3b/4b) receptor 1-like
CREB3L2 cAMP responsive element binding protein 3-like 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSO cathepsin O
CUL1 cullin 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXXC4 CXXC finger protein 4
CYBB cytochrome b-245, beta polypeptide
CYTH3 cytohesin 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DERL1 derlin 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DOCK8 dedicator of cytokinesis 8
DPCR1 diffuse panbronchiolitis critical region 1
DUSP27 dual specificity phosphatase 27 (putative)
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3H eukaryotic translation initiation factor 3, subunit H
ELAC1 elaC ribonuclease Z 1
ELP4 elongator acetyltransferase complex subunit 4
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPRS glutamyl-prolyl-tRNA synthetase
EXT1 exostosin glycosyltransferase 1
FAM118B family with sequence similarity 118, member B
FAM135B family with sequence similarity 135, member B
FAM3B family with sequence similarity 3, member B
FAM49B family with sequence similarity 49, member B
FAM83H family with sequence similarity 83, member H
FAM91A1 family with sequence similarity 91, member A1
FAT1 FAT atypical cadherin 1
FCAMR Fc receptor, IgA, IgM, high affinity
FRG2B FSHD region gene 2 family, member B
FRG2C FSHD region gene 2 family, member C
FRMD3 FERM domain containing 3
FTO fat mass and obesity associated
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GIGYF2 GRB10 interacting GYF protein 2
GLB1L2 galactosidase, beta 1-like 2
GOLIM4 golgi integral membrane protein 4
GOLPH3L golgi phosphoprotein 3-like
GPATCH2 G patch domain containing 2
GPN3 GPN-loop GTPase 3
GPR31 G protein-coupled receptor 31
GPR34 G protein-coupled receptor 34
H2AFV H2A histone family, member V
HAS2-AS1 HAS2 antisense RNA 1
HDAC9 histone deacetylase 9
HNMT histamine N-methyltransferase
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HPGDS hematopoietic prostaglandin D synthase
IGSF6 immunoglobulin superfamily, member 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL12RB1 interleukin 12 receptor, beta 1
IL6R interleukin 6 receptor
IPMK inositol polyphosphate multikinase
IPO11 importin 11
IPO5 importin 5
IPO9 importin 9
IRF8 interferon regulatory factor 8
JAK1 Janus kinase 1
JRK Jrk homolog (mouse)
JSRP1 junctional sarcoplasmic reticulum protein 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0196 KIAA0196
KIAA1147 KIAA1147
KIAA1549 KIAA1549
KIF1B kinesin family member 1B
KLHL13 kelch-like family member 13
KLHL8 kelch-like family member 8
KMT2A lysine (K)-specific methyltransferase 2A
KMT2C lysine (K)-specific methyltransferase 2C
LHFPL2 lipoma HMGIC fusion partner-like 2
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIMCH1 LIM and calponin homology domains 1
LINC00575 long intergenic non-protein coding RNA 575
LMBR1 limb development membrane protein 1
LOC100134868 uncharacterized LOC100134868
LOC285692 uncharacterized LOC285692
LRRC19 leucine rich repeat containing 19
LY86 lymphocyte antigen 86
MBD3L5 methyl-CpG binding domain protein 3-like 5
MEP1A meprin A, alpha (PABA peptide hydrolase)
METTL13 methyltransferase like 13
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MORC1 MORC family CW-type zinc finger 1
MRPS14 mitochondrial ribosomal protein S14
MSTN myostatin
MYLIP myosin regulatory light chain interacting protein
MYOZ2 myozenin 2
NALCN sodium leak channel, non selective
NBR1 neighbor of BRCA1 gene 1
NCK1 NCK adaptor protein 1
NES nestin
NHSL2 NHS-like 2
NLRP4 NLR family, pyrin domain containing 4
NME7 NME/NM23 family member 7
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPR3 natriuretic peptide receptor 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSL1 NSL1, MIS12 kinetochore complex component
NUB1 negative regulator of ubiquitin-like proteins 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUP133 nucleoporin 133kDa
OLFML3 olfactomedin-like 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR1N2 olfactory receptor, family 1, subfamily N, member 2
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR51I1 olfactory receptor, family 51, subfamily I, member 1
OR6B1 olfactory receptor, family 6, subfamily B, member 1
OR6F1 olfactory receptor, family 6, subfamily F, member 1
OR6W1P olfactory receptor, family 6, subfamily W, member 1 pseudogene
OVCH1 ovochymase 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARD3B par-3 family cell polarity regulator beta
PBX1 pre-B-cell leukemia homeobox 1
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGB4 protocadherin gamma subfamily B, 4
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDILT protein disulfide isomerase-like, testis expressed
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEA15 phosphoprotein enriched in astrocytes 15
PEX19 peroxisomal biogenesis factor 19
PHF20L1 PHD finger protein 20-like 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PLRG1 pleiotropic regulator 1
PLXDC2 plexin domain containing 2
POGK pogo transposable element with KRAB domain
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP6C protein phosphatase 6, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRAMEF11 PRAME family member 11
PRDM5 PR domain containing 5
PRRC2C proline-rich coiled-coil 2C
PRSS54 protease, serine, 54
PTAFR platelet-activating factor receptor
PTK2 protein tyrosine kinase 2
PUF60 poly-U binding splicing factor 60KDa
PWAR5 Prader Willi/Angelman region RNA 5
PWARSN Prader Willi/Angelman region RNA, SNRPN neighbor
RAB23 RAB23, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD21 RAD21 homolog (S. pombe)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RB1 retinoblastoma 1
RBM8A RNA binding motif protein 8A
RDX radixin
REPIN1 replication initiator 1
RGPD1 RANBP2-like and GRIP domain containing 1
RGS18 regulator of G-protein signaling 18
RIN2 Ras and Rab interactor 2
RNF139 ring finger protein 139
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
S100Z S100 calcium binding protein Z
SAGE1 sarcoma antigen 1
SALL2 spalt-like transcription factor 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCIN scinderin
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SELPLG selectin P ligand
SESN3 sestrin 3
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC38A4 solute carrier family 38, member 4
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SNORA2A small nucleolar RNA, H/ACA box 2A
SNORA66 small nucleolar RNA, H/ACA box 66
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNX18 sorting nexin 18
SNX2 sorting nexin 2
SNX27 sorting nexin family member 27
SOCS6 suppressor of cytokine signaling 6
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPNS3 spinster homolog 3 (Drosophila)
SSMEM1 serine-rich single-pass membrane protein 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAG1 stromal antigen 1
STAG2 stromal antigen 2
STPG2 sperm-tail PG-rich repeat containing 2
SUCO SUN domain containing ossification factor
SYK spleen tyrosine kinase
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAGAP T-cell activation RhoGTPase activating protein
TCAF1 TRPM8 channel-associated factor 1
TCHHL1 trichohyalin-like 1
TENM4 teneurin transmembrane protein 4
THEM6 thioesterase superfamily member 6
TIGD4 tigger transposable element derived 4
TLR10 toll-like receptor 10
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TM9SF2 transmembrane 9 superfamily member 2
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMEM52B transmembrane protein 52B
TMEM86A transmembrane protein 86A
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOP2B topoisomerase (DNA) II beta 180kDa
TOR1AIP1 torsin A interacting protein 1
TPP2 tripeptidyl peptidase II
TPR translocated promoter region, nuclear basket protein
TRAM2 translocation associated membrane protein 2
TRIM58 tripartite motif containing 58
TRIM64 tripartite motif containing 64
TRIP11 thyroid hormone receptor interactor 11
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TUBGCP3 tubulin, gamma complex associated protein 3
TWISTNB TWIST neighbor
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE3C ubiquitin protein ligase E3C
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP2 ubiquitin specific peptidase 2
USP8 ubiquitin specific peptidase 8
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast)
VANGL2 VANGL planar cell polarity protein 2
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
WDFY4 WDFY family member 4
WDR48 WD repeat domain 48
WDYHV1 WDYHV motif containing 1
WWTR1 WW domain containing transcription regulator 1
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFAT-AS1 ZFAT antisense RNA 1
ZHX1 zinc fingers and homeoboxes 1
ZHX2 zinc fingers and homeoboxes 2
ZNF16 zinc finger protein 16
ZNF212 zinc finger protein 212
ZNF250 zinc finger protein 250
ZNF252P zinc finger protein 252, pseudogene
ZNF281 zinc finger protein 281
ZNF317 zinc finger protein 317
ZNF398 zinc finger protein 398
ZNF425 zinc finger protein 425
ZNF546 zinc finger protein 546
ZNF572 zinc finger protein 572
ZNF619 zinc finger protein 619
ZNF623 zinc finger protein 623
ZNF696 zinc finger protein 696
ZNF7 zinc finger protein 7
ZNF746 zinc finger protein 746
ZNF862 zinc finger protein 862
ZNHIT6 zinc finger, HIT-type containing 6
ZSWIM5 zinc finger, SWIM-type containing 5

low expression

Symbol Name
GRK4 G protein-coupled receptor kinase 4
SH3BP5L SH3-binding domain protein 5-like
TBCE tubulin folding cofactor E