Brain Lower Grade Glioma_LGG_TCGA-DU-5872-01A-11R-1708-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

355 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-5872-01A-11R-1708-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABLIM3 actin binding LIM protein family, member 3
ACAT1 acetyl-CoA acetyltransferase 1
ACHE acetylcholinesterase (Yt blood group)
ACO2 aconitase 2, mitochondrial
ACSF3 acyl-CoA synthetase family member 3
ACTRT3 actin-related protein T3
ADCY2 adenylate cyclase 2 (brain)
AKAP1 A kinase (PRKA) anchor protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMPD1 adenosine monophosphate deaminase 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL2 angiopoietin-like 2
ANO10 anoctamin 10
AP3M2 adaptor-related protein complex 3, mu 2 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASB17 ankyrin repeat and SOCS box containing 17
ASTN2 astrotactin 2
ATF5 activating transcription factor 5
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BLVRB biliverdin reductase B
BMP2K BMP2 inducible kinase
C14ORF93 chromosome 14 open reading frame 93
CALHM2 calcium homeostasis modulator 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP12 caspase 12 (gene/pseudogene)
CCBL2 cysteine conjugate-beta lyase 2
CCDC136 coiled-coil domain containing 136
CCPG1 cell cycle progression 1
CD200R1 CD200 receptor 1
CD28 CD28 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CFHR1 complement factor H-related 1
CHPF chondroitin polymerizing factor
COA7 cytochrome c oxidase assembly factor 7 (putative)
COG5 component of oligomeric golgi complex 5
COQ9 coenzyme Q9
COX18 COX18 cytochrome c oxidase assembly factor
CPB1 carboxypeptidase B1 (tissue)
CPT2 carnitine palmitoyltransferase 2
CRISP3 cysteine-rich secretory protein 3
CRTAP cartilage associated protein
CRTC3 CREB regulated transcription coactivator 3
CRYAB crystallin, alpha B
CRYL1 crystallin, lambda 1
CS citrate synthase
CT45A1 cancer/testis antigen family 45, member A1
CT45A3 cancer/testis antigen family 45, member A3
CT45A5 cancer/testis antigen family 45, member A5
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DLD dihydrolipoamide dehydrogenase
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNAL4 dynein, axonemal, light chain 4
DNPEP aspartyl aminopeptidase
DPCR1 diffuse panbronchiolitis critical region 1
DPH5 diphthamide biosynthesis 5
DPH6 diphthamine biosynthesis 6
DPRXP4 divergent-paired related homeobox pseudogene 4
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DUSP19 dual specificity phosphatase 19
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EFTUD1 elongation factor Tu GTP binding domain containing 1
EGF epidermal growth factor
ENAH enabled homolog (Drosophila)
EPHA3 EPH receptor A3
EPHB1 EPH receptor B1
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
EXPH5 exophilin 5
FAM162A family with sequence similarity 162, member A
FAM35A family with sequence similarity 35, member A
FAM35BP family with sequence similarity 35, member A pseudogene
FBXO6 F-box protein 6
FBXW4 F-box and WD repeat domain containing 4
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOXL2 forkhead box L2
FOXL2NB FOXL2 neighbor
FOXP2 forkhead box P2
FOXQ1 forkhead box Q1
FRMD5 FERM domain containing 5
FXN frataxin
GALK2 galactokinase 2
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GBP6 guanylate binding protein family, member 6
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLB1 galactosidase, beta 1
GMPR2 guanosine monophosphate reductase 2
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP2 glycoprotein 2 (zymogen granule membrane)
GPX3 glutathione peroxidase 3
GTF2IRD1 GTF2I repeat domain containing 1
GTPBP10 GTP-binding protein 10 (putative)
HADH hydroxyacyl-CoA dehydrogenase
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HARBI1 harbinger transposase derived 1
HAUS4 HAUS augmin-like complex, subunit 4
HAX1 HCLS1 associated protein X-1
HBB hemoglobin, beta
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIST1H2AK histone cluster 1, H2ak
HIST3H2A histone cluster 3, H2a
HOMEZ homeobox and leucine zipper encoding
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IAPP islet amyloid polypeptide
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFRD1 interferon-related developmental regulator 1
IGFBP5 insulin-like growth factor binding protein 5
INSL4 insulin-like 4 (placenta)
INSL6 insulin-like 6
ISX intestine-specific homeobox
IVD isovaleryl-CoA dehydrogenase
KAAG1 kidney associated antigen 1
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KDSR 3-ketodihydrosphingosine reductase
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA0100 KIAA0100
KIAA0391 KIAA0391
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KLK4 kallikrein-related peptidase 4
KLKP1 kallikrein pseudogene 1
KRTAP5-5 keratin associated protein 5-5
L2HGDH L-2-hydroxyglutarate dehydrogenase
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LINC00324 long intergenic non-protein coding RNA 324
LOC100268168 uncharacterized LOC100268168
LONP2 lon peptidase 2, peroxisomal
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRRN4CL LRRN4 C-terminal like
LTA4H leukotriene A4 hydrolase
MANBA mannosidase, beta A, lysosomal
MANEAL mannosidase, endo-alpha-like
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
METTL5 methyltransferase like 5
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MIPEP mitochondrial intermediate peptidase
MIXL1 Mix paired-like homeobox
MMRN2 multimerin 2
MPEG1 macrophage expressed 1
MRPL3 mitochondrial ribosomal protein L3
MRPS18B mitochondrial ribosomal protein S18B
MRPS22 mitochondrial ribosomal protein S22
MRPS27 mitochondrial ribosomal protein S27
MSMB microseminoprotein, beta-
MSRB3 methionine sulfoxide reductase B3
MTMR11 myotubularin related protein 11
MYCT1 myc target 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NAGLU N-acetylglucosaminidase, alpha
NFE2L1 nuclear factor, erythroid 2-like 1
NFS1 NFS1 cysteine desulfurase
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLRP12 NLR family, pyrin domain containing 12
NNT nicotinamide nucleotide transhydrogenase
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOMO1 NODAL modulator 1
NOTCH2NL notch 2 N-terminal like
NQO2 NAD(P)H dehydrogenase, quinone 2
NSRP1 nuclear speckle splicing regulatory protein 1
NUBPL nucleotide binding protein-like
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR1L1 olfactory receptor, family 1, subfamily L, member 1
OR1N2 olfactory receptor, family 1, subfamily N, member 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTC ornithine carbamoyltransferase
OXCT1 3-oxoacid CoA transferase 1
OXNAD1 oxidoreductase NAD-binding domain containing 1
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PAQR3 progestin and adipoQ receptor family member III
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCA3 prostate cancer associated 3 (non-protein coding)
PCCA propionyl CoA carboxylase, alpha polypeptide
PCGEM1 PCGEM1, prostate-specific transcript (non-protein coding)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCYOX1L prenylcysteine oxidase 1 like
PDCD2L programmed cell death 2-like
PDE4DIP phosphodiesterase 4D interacting protein
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHX pyruvate dehydrogenase complex, component X
PDILT protein disulfide isomerase-like, testis expressed
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX19 peroxisomal biogenesis factor 19
PFKM phosphofructokinase, muscle
PGLYRP3 peptidoglycan recognition protein 3
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMCHL2 pro-melanin-concentrating hormone-like 2, pseudogene
POM121L2 POM121 transmembrane nucleoporin-like 2
PORCN porcupine homolog (Drosophila)
PPA2 pyrophosphatase (inorganic) 2
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PPT1 palmitoyl-protein thioesterase 1
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRUNE2 prune homolog 2 (Drosophila)
PSAP prosaposin
PSAPL1 prosaposin-like 1 (gene/pseudogene)
PSG2 pregnancy specific beta-1-glycoprotein 2
PSKH1 protein serine kinase H1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTCD1 pentatricopeptide repeat domain 1
PTCD2 pentatricopeptide repeat domain 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTHLH parathyroid hormone-like hormone
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QRFPR pyroglutamylated RFamide peptide receptor
RAB23 RAB23, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RASA4 RAS p21 protein activator 4
RASA4CP RAS p21 protein activator 4C, pseudogene
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RCL1 RNA terminal phosphate cyclase-like 1
RIPK2 receptor-interacting serine-threonine kinase 2
RLN2 relaxin 2
RNASE4 ribonuclease, RNase A family, 4
RNASEH2B ribonuclease H2, subunit B
RNF182 ring finger protein 182
RNF187 ring finger protein 187
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS26 ribosomal protein S26
RPS26P11 ribosomal protein S26 pseudogene 11
SARS seryl-tRNA synthetase
SCO1 SCO1 cytochrome c oxidase assembly protein
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans)
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHE Src homology 2 domain containing E
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A14 solute carrier family 16, member 14
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLFN5 schlafen family member 5
SND1 staphylococcal nuclease and tudor domain containing 1
SNORA78 small nucleolar RNA, H/ACA box 78
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX18 SRY (sex determining region Y)-box 18
SOX7 SRY (sex determining region Y)-box 7
SPANXN1 SPANX family, member N1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPIRE1 spire-type actin nucleation factor 1
STRADB STE20-related kinase adaptor beta
STX3 syntaxin 3
STYXL1 serine/threonine/tyrosine interacting-like 1
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SYNPO2 synaptopodin 2
SYPL2 synaptophysin-like 2
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAGAP T-cell activation RhoGTPase activating protein
TANGO2 transport and golgi organization 2 homolog (Drosophila)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TAS2R13 taste receptor, type 2, member 13
TCP10L t-complex 10-like
TCTE1 t-complex-associated-testis-expressed 1
TCTN3 tectonic family member 3
TFF1 trefoil factor 1
THAP10 THAP domain containing 10
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIGD6 tigger transposable element derived 6
TMEM55A transmembrane protein 55A
TMEM92 transmembrane protein 92
TMPRSS2 transmembrane protease, serine 2
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX2 TOX high mobility group box family member 2
TP53RK TP53 regulating kinase
TP53TG1 TP53 target 1 (non-protein coding)
TPK1 thiamin pyrophosphokinase 1
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRAP1 TNF receptor-associated protein 1
TRAPPC3L trafficking protein particle complex 3-like
TRIM4 tripartite motif containing 4
TRIM56 tripartite motif containing 56
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRUB2 TruB pseudouridine (psi) synthase family member 2
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TSPAN1 tetraspanin 1
TTC39A tetratricopeptide repeat domain 39A
TUBAL3 tubulin, alpha-like 3
TYW5 tRNA-yW synthesizing protein 5
UBE2E1 ubiquitin-conjugating enzyme E2E 1
VTCN1 V-set domain containing T cell activation inhibitor 1
VWA8 von Willebrand factor A domain containing 8
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR87 WD repeat domain 87
XIRP2 xin actin binding repeat containing 2
XPOT exportin, tRNA
YIPF7 Yip1 domain family, member 7
YOD1 YOD1 deubiquitinase
ZDHHC1 zinc finger, DHHC-type containing 1
ZDHHC3 zinc finger, DHHC-type containing 3
ZFAND4 zinc finger, AN1-type domain 4
ZNF267 zinc finger protein 267
ZNF330 zinc finger protein 330
ZNF382 zinc finger protein 382
ZNF425 zinc finger protein 425
ZNF503-AS2 ZNF503 antisense RNA 2
ZNF804A zinc finger protein 804A
ZNF843 zinc finger protein 843

low expression

Symbol Name
ATG5 autophagy related 5
ATXN3 ataxin 3
CCNC cyclin C
CIR1 corepressor interacting with RBPJ, 1
DHRS4-AS1 DHRS4 antisense RNA 1
ECHDC1 ethylmalonyl-CoA decarboxylase 1
MARK3 MAP/microtubule affinity-regulating kinase 3
MED6 mediator complex subunit 6
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
PEX3 peroxisomal biogenesis factor 3
RNF146 ring finger protein 146
SENP6 SUMO1/sentrin specific peptidase 6
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
TPMT thiopurine S-methyltransferase
WDR20 WD repeat domain 20