Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

333 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
AFF3 AF4/FMR2 family, member 3
AGBL1 ATP/GTP binding protein-like 1
AHCTF1 AT hook containing transcription factor 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
AMER1 APC membrane recruitment protein 1
ANKRD52 ankyrin repeat domain 52
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B
ANO6 anoctamin 6
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
ATL3 atlastin GTPase 3
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD7 BTB (POZ) domain containing 7
C10ORF2 chromosome 10 open reading frame 2
C11ORF42 chromosome 11 open reading frame 42
C1ORF109 chromosome 1 open reading frame 109
C4ORF51 chromosome 4 open reading frame 51
C9ORF41 chromosome 9 open reading frame 41
CAMK1D calcium/calmodulin-dependent protein kinase ID
CDH7 cadherin 7, type 2
CIB4 calcium and integrin binding family member 4
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLEC2L C-type lectin domain family 2, member L
CLK2P1 CDC-like kinase 2, pseudogene 1
CLMP CXADR-like membrane protein
CLOCK clock circadian regulator
CLPTM1 cleft lip and palate associated transmembrane protein 1
CMA1 chymase 1, mast cell
CNBD1 cyclic nucleotide binding domain containing 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COLEC10 collectin sub-family member 10 (C-type lectin)
CORT cortistatin
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX7B2 cytochrome c oxidase subunit VIIb2
CRHBP corticotropin releasing hormone binding protein
CSNK1A1L casein kinase 1, alpha 1-like
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CTSG cathepsin G
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDR2 discoidin domain receptor tyrosine kinase 2
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DGKH diacylglycerol kinase, eta
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DIAPH2 diaphanous-related formin 2
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
EAF1 ELL associated factor 1
EDARADD EDAR-associated death domain
EDNRA endothelin receptor type A
EFR3B EFR3 homolog B (S. cerevisiae)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EMC1 ER membrane protein complex subunit 1
ENAM enamelin
ETV3L ets variant 3-like
F2R coagulation factor II (thrombin) receptor
FAM160B1 family with sequence similarity 160, member B1
FAM163B family with sequence similarity 163, member B
FAM175B family with sequence similarity 175, member B
FAM182A family with sequence similarity 182, member A
FAM47A family with sequence similarity 47, member A
FAM92A1P2 family with sequence similarity 92, member A3
FAT1 FAT atypical cadherin 1
FER1L6 fer-1-like family member 6
FMN1 formin 1
FRMD3 FERM domain containing 3
FSHR follicle stimulating hormone receptor
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADL1 glutamate decarboxylase-like 1
GBP6 guanylate binding protein family, member 6
GJB4 gap junction protein, beta 4, 30.3kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR149 G protein-coupled receptor 149
GPR176 G protein-coupled receptor 176
GPR26 G protein-coupled receptor 26
GPR68 G protein-coupled receptor 68
GREM2 gremlin 2, DAN family BMP antagonist
GSTTP2 glutathione S-transferase theta pseudogene 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCRTR1 hypocretin (orexin) receptor 1
HFE2 hemochromatosis type 2 (juvenile)
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
HTN3 histatin 3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
IFNA8 interferon, alpha 8
IGFBP1 insulin-like growth factor binding protein 1
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
IL5 interleukin 5
IMPAD1 inositol monophosphatase domain containing 1
INSL6 insulin-like 6
IPMK inositol polyphosphate multikinase
IQCJ IQ motif containing J
KAZN kazrin, periplakin interacting protein
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KIAA1958 KIAA1958
KLHL40 kelch-like family member 40
KRT34 keratin 34, type I
KRTAP3-2 keratin associated protein 3-2
KRTAP7-1 keratin associated protein 7-1 (gene/pseudogene)
KRTAP8-1 keratin associated protein 8-1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMC2 laminin, gamma 2
LATS1 large tumor suppressor kinase 1
LGI2 leucine-rich repeat LGI family, member 2
LINC00207 long intergenic non-protein coding RNA 207
LINC00589 long intergenic non-protein coding RNA 589
LINC01555 long intergenic non-protein coding RNA 1555
LMOD3 leiomodin 3 (fetal)
LNPEP leucyl/cystinyl aminopeptidase
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC284441 actin-related protein 2 pseudogene
LOC340357 uncharacterized LOC340357
LOC344967 acyl-CoA thioesterase 7 pseudogene
LOC407835 mitogen-activated protein kinase kinase 2 pseudogene
LOC649330
LOXHD1 lipoxygenase homology domains 1
LRP12 low density lipoprotein receptor-related protein 12
LYZL4 lysozyme-like 4
MAN1A2 mannosidase, alpha, class 1A, member 2
MANEAL mannosidase, endo-alpha-like
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MC3R melanocortin 3 receptor
MEPE matrix extracellular phosphoglycoprotein
MIEF1 mitochondrial elongation factor 1
MLIP muscular LMNA-interacting protein
MPO myeloperoxidase
NAV2 neuron navigator 2
NCOA2 nuclear receptor coactivator 2
NCOR1 nuclear receptor corepressor 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NHLRC2 NHL repeat containing 2
NHSL2 NHS-like 2
NNAT neuronatin
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH2 notch 2
NOTCH2NL notch 2 N-terminal like
NPTX2 neuronal pentraxin II
NPTXR neuronal pentraxin receptor
NRAP nebulin-related anchoring protein
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2
OPN4 opsin 4
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR4D10 olfactory receptor, family 4, subfamily D, member 10
OR4K5 olfactory receptor, family 4, subfamily K, member 5
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR52H1 olfactory receptor, family 52, subfamily H, member 1
OR6C4 olfactory receptor, family 6, subfamily C, member 4
OSTN osteocrin
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PABPC3 poly(A) binding protein, cytoplasmic 3
PARD3B par-3 family cell polarity regulator beta
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCDH7 protocadherin 7
PCDHA6 protocadherin alpha 6
PCDHGA10 protocadherin gamma subfamily A, 10
PCP4L1 Purkinje cell protein 4 like 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PCYOX1 prenylcysteine oxidase 1
PDZD8 PDZ domain containing 8
PEG3-AS1 PEG3 antisense RNA 1
PENK proenkephalin
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGAM4 phosphoglycerate mutase family member 4
PGM2L1 phosphoglucomutase 2-like 1
PHOX2A paired-like homeobox 2a
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1P1 phosphatidylinositol-4-phosphate 5-kinase, type I, pseudogene 1
PKNOX2 PBX/knotted 1 homeobox 2
PLBD2 phospholipase B domain containing 2
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PMCH pro-melanin-concentrating hormone
PMP2 peripheral myelin protein 2
PNOC prepronociceptin
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
POU5F2 POU domain class 5, transcription factor 2
PPIAL4D peptidylprolyl isomerase A (cyclophilin A)-like 4D
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRDM4 PR domain containing 4
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRRC2B proline-rich coiled-coil 2B
PRRX1 paired related homeobox 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTHLH parathyroid hormone-like hormone
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPRG protein tyrosine phosphatase, receptor type, G
PURA purine-rich element binding protein A
R3HDML R3H domain containing-like
RAB3B RAB3B, member RAS oncogene family
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RNASEH1 ribonuclease H1
RNF217 ring finger protein 217
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPL13AP6 ribosomal protein L13a pseudogene 6
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL29P2 ribosomal protein L29 pseudogene 2
RPLP0P2 ribosomal protein, large, P0 pseudogene 2
RPS4Y2 ribosomal protein S4, Y-linked 2
RSC1A1 regulatory solute carrier protein, family 1, member 1
RTL1 retrotransposon-like 1
RXFP3 relaxin/insulin-like family peptide receptor 3
S100G S100 calcium binding protein G
SAMD8 sterile alpha motif domain containing 8
SBF1P1 SET binding factor 1 pseudogene 1
SCARNA21 small Cajal body-specific RNA 21
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SETBP1 SET binding protein 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SH3RF2 SH3 domain containing ring finger 2
SIKE1 suppressor of IKBKE 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC35E2 solute carrier family 35, member E2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17
SNIP1 Smad nuclear interacting protein 1
SNORA44 small nucleolar RNA, H/ACA box 44
SNORA77 small nucleolar RNA, H/ACA box 77
SNORD115-7 small nucleolar RNA, C/D box 115-7
SOCS7 suppressor of cytokine signaling 7
SORCS1 sortilin-related VPS10 domain containing receptor 1
SPATA31E1 SPATA31 subfamily E, member 1
SPRR1A small proline-rich protein 1A
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
STAT5B signal transducer and activator of transcription 5B
STON1-GTF2A1L STON1-GTF2A1L readthrough
SV2C synaptic vesicle glycoprotein 2C
SYT12 synaptotagmin XII
TAC1 tachykinin, precursor 1
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAOK1 TAO kinase 1
TDO2 tryptophan 2,3-dioxygenase
TENM2 teneurin transmembrane protein 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM127 transmembrane protein 127
TMEM164 transmembrane protein 164
TMEM170B transmembrane protein 170B
TMEM225 transmembrane protein 225
TMEM233 transmembrane protein 233
TMEM244 transmembrane protein 244
TMPPE transmembrane protein with metallophosphoesterase domain
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNS3 tensin 3
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM35 tripartite motif containing 35
TRNP1 TMF1-regulated nuclear protein 1
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC28 tetratricopeptide repeat domain 28
TTC9 tetratricopeptide repeat domain 9
TTLL8 tubulin tyrosine ligase-like family member 8
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UHMK1 U2AF homology motif (UHM) kinase 1
UTS2 urotensin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VN1R4 vomeronasal 1 receptor 4
VSX2 visual system homeobox 2
WBP11P1 WW domain binding protein 11 pseudogene 1
XKRY2 XK, Kell blood group complex subunit-related, Y-linked 2
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBTB10 zinc finger and BTB domain containing 10
ZBTB21 zinc finger and BTB domain containing 21
ZBTB39 zinc finger and BTB domain containing 39
ZCCHC2 zinc finger, CCHC domain containing 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF134 zinc finger protein 134
ZNF142 zinc finger protein 142
ZNF324 zinc finger protein 324
ZNF324B zinc finger protein 324B
ZNF329 zinc finger protein 329
ZNF385D zinc finger protein 385D
ZNF416 zinc finger protein 416
ZNF526 zinc finger protein 526
ZNF543 zinc finger protein 543
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF584 zinc finger protein 584
ZNF749 zinc finger protein 749
ZNF770 zinc finger protein 770
ZPBP zona pellucida binding protein
ZSCAN20 zinc finger and SCAN domain containing 20

low expression

Symbol Name
ACAD9 acyl-CoA dehydrogenase family, member 9
ATG3 autophagy related 3
CBWD2 COBW domain containing 2
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
RAB9A RAB9A, member RAS oncogene family
TFG TRK-fused gene
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
UBA5 ubiquitin-like modifier activating enzyme 5