Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

349 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ABHD6 abhydrolase domain containing 6
ABLIM3 actin binding LIM protein family, member 3
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADD3 adducin 3 (gamma)
ADK adenosine kinase
AGGF1 angiogenic factor with G patch and FHA domains 1
AKAP10 A kinase (PRKA) anchor protein 10
AKAP3 A kinase (PRKA) anchor protein 3
AKR1B15 aldo-keto reductase family 1, member B15
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPTL1 angiopoietin-like 1
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ANXA2P1 annexin A2 pseudogene 1
ANXA2P3 annexin A2 pseudogene 3
ANXA6 annexin A6
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AQP4 aquaporin 4
ARHGAP6 Rho GTPase activating protein 6
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ART5 ADP-ribosyltransferase 5
ASCC1 activating signal cointegrator 1 complex subunit 1
ASIP agouti signaling protein
ASUN asunder spermatogenesis regulator
ATP5EP2 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
B3GALTL beta 1,3-galactosyltransferase-like
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
B9D1 B9 protein domain 1
BBS12 Bardet-Biedl syndrome 12
BCL2L13 BCL2-like 13 (apoptosis facilitator)
C11ORF52 chromosome 11 open reading frame 52
C14ORF1 chromosome 14 open reading frame 1
C14ORF37 chromosome 14 open reading frame 37
C17ORF98 chromosome 17 open reading frame 98
C1ORF94 chromosome 1 open reading frame 94
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF15 chromosome 2 open reading frame 15
C3ORF38 chromosome 3 open reading frame 38
C9ORF153 chromosome 9 open reading frame 153
CABLES1 Cdk5 and Abl enzyme substrate 1
CAPN1 calpain 1, (mu/I) large subunit
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CBY1 chibby homolog 1 (Drosophila)
CCDC103 coiled-coil domain containing 103
CCDC80 coiled-coil domain containing 80
CD38 CD38 molecule
CD99 CD99 molecule
CFAP36 cilia and flagella associated protein 36
CLEC18C C-type lectin domain family 18, member C
CLK2P1 CDC-like kinase 2, pseudogene 1
CNTF ciliary neurotrophic factor
COMMD2 COMM domain containing 2
COMMD9 COMM domain containing 9
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPT2 carnitine palmitoyltransferase 2
CRYAB crystallin, alpha B
CSNK1A1L casein kinase 1, alpha 1-like
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXADRP2 coxsackie virus and adenovirus receptor pseudogene 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DCLK2 doublecortin-like kinase 2
DDR2 discoidin domain receptor tyrosine kinase 2
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DEFB132 defensin, beta 132
DEGS1 delta(4)-desaturase, sphingolipid 1
DERA deoxyribose-phosphate aldolase (putative)
DFNA5 deafness, autosomal dominant 5
DHFR dihydrofolate reductase
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPYSL3 dihydropyrimidinase-like 3
DUSP14 dual specificity phosphatase 14
DUSP27 dual specificity phosphatase 27 (putative)
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLT1 dynein, light chain, Tctex-type 1
ECI2 enoyl-CoA delta isomerase 2
EDARADD EDAR-associated death domain
EDNRA endothelin receptor type A
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EHD1 EH-domain containing 1
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF5B eukaryotic translation initiation factor 5B
ELAC2 elaC ribonuclease Z 2
ENAH enabled homolog (Drosophila)
ERC1 ELKS/RAB6-interacting/CAST family member 1
EZR ezrin
FADD Fas (TNFRSF6)-associated via death domain
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM105A family with sequence similarity 105, member A
FAM136BP family with sequence similarity 136, member B, pseudogene
FAM167A family with sequence similarity 167, member A
FAM188B family with sequence similarity 188, member B
FAM83H family with sequence similarity 83, member H
FAM90A1 family with sequence similarity 90, member A1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXL14 F-box and leucine-rich repeat protein 14
FBXO8 F-box protein 8
FLJ16779 uncharacterized LOC100192386
FLJ44635 TPT1-like protein
FNTB farnesyltransferase, CAAX box, beta
FSD1L fibronectin type III and SPRY domain containing 1-like
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GDE1 glycerophosphodiester phosphodiesterase 1
GDF1 growth differentiation factor 1
GDF11 growth differentiation factor 11
GFAP glial fibrillary acidic protein
GLIPR2 GLI pathogenesis-related 2
GLUD2 glutamate dehydrogenase 2
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPM6B glycoprotein M6B
GPR19 G protein-coupled receptor 19
GPRC5B G protein-coupled receptor, class C, group 5, member B
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GRHL3 grainyhead-like 3 (Drosophila)
GSTM1 glutathione S-transferase mu 1
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GYG1 glycogenin 1
HBBP1 hemoglobin, beta pseudogene 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H3E histone cluster 1, H3e
HNMT histamine N-methyltransferase
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNL3 interferon, lambda 3
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IL33 interleukin 33
ITSN1 intersectin 1 (SH3 domain protein)
JAK1 Janus kinase 1
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNK13 potassium channel, two pore domain subfamily K, member 13
KIAA2013 KIAA2013
KIF3B kinesin family member 3B
KLHDC8B kelch domain containing 8B
KLHL5 kelch-like family member 5
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRTAP1-3 keratin associated protein 1-3
KRTAP5-6 keratin associated protein 5-6
LASP1 LIM and SH3 protein 1
LCAT lecithin-cholesterol acyltransferase
LDHB lactate dehydrogenase B
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIMK2 LIM domain kinase 2
LIX1 Lix1 homolog (chicken)
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC341056 SUMO1 activating enzyme subunit 1 pseudogene
LOC407835 mitogen-activated protein kinase kinase 2 pseudogene
LOC644172 mitogen-activated protein kinase 8 interacting protein 1 pseudogene
LOC646999 akirin 1 pseudogene
LOC649330
LOC728392 uncharacterized LOC728392
LRRC42 leucine rich repeat containing 42
LRRC52 leucine rich repeat containing 52
LYRM5 LYR motif containing 5
MAP4 microtubule-associated protein 4
MAPK7 mitogen-activated protein kinase 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MEGF8 multiple EGF-like-domains 8
MEX3C mex-3 RNA binding family member C
MGC16275 uncharacterized protein MGC16275
MGC72080 MGC72080 pseudogene
MGST1 microsomal glutathione S-transferase 1
MIPEP mitochondrial intermediate peptidase
MLIP muscular LMNA-interacting protein
MTCH2 mitochondrial carrier 2
MXRA5 matrix-remodelling associated 5
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NATD1 N-acetyltransferase domain containing 1
NECAP2 NECAP endocytosis associated 2
NIFK nucleolar protein interacting with the FHA domain of MKI67
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NKAIN4 Na+/K+ transporting ATPase interacting 4
NMB neuromedin B
NME2P1 NME/NM23 nucleoside diphosphate kinase 2 pseudogene 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR2M2 olfactory receptor, family 2, subfamily M, member 2
OR4F4 olfactory receptor, family 4, subfamily F, member 4
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR52N2 olfactory receptor, family 52, subfamily N, member 2
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
OSTCP1 oligosaccharyltransferase complex subunit pseudogene 1
OXA1L oxidase (cytochrome c) assembly 1-like
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PABPC3 poly(A) binding protein, cytoplasmic 3
PCDHA4 protocadherin alpha 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PDHB pyruvate dehydrogenase (lipoamide) beta
PEA15 phosphoprotein enriched in astrocytes 15
PEX10 peroxisomal biogenesis factor 10
PFDN1 prefoldin subunit 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGD phosphogluconate dehydrogenase
PHF23 PHD finger protein 23
PIP5K1P1 phosphatidylinositol-4-phosphate 5-kinase, type I, pseudogene 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLRG1 pleiotropic regulator 1
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
POU1F1 POU class 1 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRAF2 PRA1 domain family, member 2
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRR5L proline rich 5 like
PSAT1 phosphoserine aminotransferase 1
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PTBP2 polypyrimidine tract binding protein 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXYLP1 2-phosphoxylose phosphatase 1
RAB13 RAB13, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RAD51B RAD51 paralog B
RAVER2 ribonucleoprotein, PTB-binding 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RDX radixin
REP15 RAB15 effector protein
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RMDN1 regulator of microtubule dynamics 1
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL13AP6 ribosomal protein L13a pseudogene 6
RPL19P12 ribosomal protein L19 pseudogene 12
RPL29P2 ribosomal protein L29 pseudogene 2
RPL31P11 ribosomal protein L31 pseudogene 11
RWDD2B RWD domain containing 2B
S1PR3 sphingosine-1-phosphate receptor 3
SAMD4A sterile alpha motif domain containing 4A
SAP18 Sin3A-associated protein, 18kDa
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCHIP1 schwannomin interacting protein 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SELPLG selectin P ligand
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEPN1 selenoprotein N, 1
SFRP2 secreted frizzled-related protein 2
SGPL1 sphingosine-1-phosphate lyase 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC16A4 solute carrier family 16, member 4
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC44A3 solute carrier family 44, member 3
SLC51A solute carrier family 51, alpha subunit
SMAD6 SMAD family member 6
SMCP sperm mitochondria-associated cysteine-rich protein
SMG6 SMG6 nonsense mediated mRNA decay factor
SNAPIN SNAP-associated protein
SNX18 sorting nexin 18
SNX3 sorting nexin 3
SORBS1 sorbin and SH3 domain containing 1
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPO11 SPO11 meiotic protein covalently bound to DSB
SPON1 spondin 1, extracellular matrix protein
SRR serine racemase
ST5 suppression of tumorigenicity 5
STRAP serine/threonine kinase receptor associated protein
SULF1 sulfatase 1
SUMO3 small ubiquitin-like modifier 3
SUOX sulfite oxidase
SUSD3 sushi domain containing 3
SYNM synemin, intermediate filament protein
SYNPO2 synaptopodin 2
TAGAP T-cell activation RhoGTPase activating protein
TBCK TBC1 domain containing kinase
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2
TDRD7 tudor domain containing 7
TEX261 testis expressed 261
TFDP1 transcription factor Dp-1
TFE3 transcription factor binding to IGHM enhancer 3
TGFBI transforming growth factor, beta-induced, 68kDa
TMC1 transmembrane channel-like 1
TMEM11 transmembrane protein 11
TMEM174 transmembrane protein 174
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNIP2 TNFAIP3 interacting protein 2
TPH1 tryptophan hydroxylase 1
TPST1 tyrosylprotein sulfotransferase 1
TPST2 tyrosylprotein sulfotransferase 2
TSPAN3 tetraspanin 3
TSPY1 testis specific protein, Y-linked 1
TUBA1A tubulin, alpha 1a
UBE2A ubiquitin-conjugating enzyme E2A
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBTD1 ubiquitin domain containing 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP22 ubiquitin specific peptidase 22
USP50 ubiquitin specific peptidase 50
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VEPH1 ventricular zone expressed PH domain-containing 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WBP11 WW domain binding protein 11
WBP11P1 WW domain binding protein 11 pseudogene 1
WLS wntless Wnt ligand secretion mediator
WNK1 WNK lysine deficient protein kinase 1
WWTR1 WW domain containing transcription regulator 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZDHHC16 zinc finger, DHHC-type containing 16
ZDHHC3 zinc finger, DHHC-type containing 3
ZFAND3 zinc finger, AN1-type domain 3
ZNF252P zinc finger protein 252, pseudogene
ZNF792 zinc finger protein 792
ZNF823 zinc finger protein 823
ZNF90 zinc finger protein 90

low expression

Symbol Name
CCDC120 coiled-coil domain containing 120
HARS2 histidyl-tRNA synthetase 2, mitochondrial
KRBOX4 KRAB box domain containing 4
NEURL4 neuralized E3 ubiquitin protein ligase 4
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PPP6R2 protein phosphatase 6, regulatory subunit 2
ZC3H7B zinc finger CCCH-type containing 7B
ZFAND1 zinc finger, AN1-type domain 1
ZNF335 zinc finger protein 335
ZNF630 zinc finger protein 630
ZNF772 zinc finger protein 772