Bone Diseases, Metabolic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D001851
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Genes

120 genes/proteins associated with the disease Bone Diseases, Metabolic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
MMP2 matrix metallopeptidase 2 2.88009
ANKRD11 ankyrin repeat domain 11 2.88009
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.88009
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 2.88009
CTC1 CTS telomere maintenance complex component 1 2.88009
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.88009
IGF1 insulin-like growth factor 1 (somatomedin C) 2.88009
LRP2 low density lipoprotein receptor-related protein 2 2.88009
GC group-specific component (vitamin D binding protein) 2.88009
ESR1 estrogen receptor 1 2.88009
DHCR7 7-dehydrocholesterol reductase 2.88009
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.42723
TGFB2 transforming growth factor, beta 2 1.39226
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.38918
PTH parathyroid hormone 1.37075
TGFB1 transforming growth factor, beta 1 1.36275
PRLR prolactin receptor 1.31686
BGLAP bone gamma-carboxyglutamate (gla) protein 1.31686
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.31327
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.29966
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.28889
EPHX2 epoxide hydrolase 2, cytoplasmic 1.27626
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.27595
FOS FBJ murine osteosarcoma viral oncogene homolog 1.27502
CCL2 chemokine (C-C motif) ligand 2 1.26825
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.26607
BCL2 B-cell CLL/lymphoma 2 1.25899
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.24874
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.24024
TNF tumor necrosis factor 1.23233
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.23042
JUN jun proto-oncogene 1.21951
MAPK8 mitogen-activated protein kinase 8 1.21727
CCND1 cyclin D1 1.21501
COL1A2 collagen, type I, alpha 2 1.21173
IL6 interleukin 6 1.2046
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.20097
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.20097
IGFBP3 insulin-like growth factor binding protein 3 1.19179
GSTM2 glutathione S-transferase mu 2 (muscle) 1.18126
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.18059
CDC6 cell division cycle 6 1.17926
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.17728
RPA2 replication protein A2, 32kDa 1.17333
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.16733
RB1 retinoblastoma 1 1.16401
INHBA inhibin, beta A 1.16335
BAD BCL2-associated agonist of cell death 1.16203
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.1607
VIM vimentin 1.15492
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.14816
ALB albumin 1.14234
ADIPOQ adiponectin, C1Q and collagen domain containing 1.14132
FBXL3 F-box and leucine-rich repeat protein 3 1.1403
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.13415
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.13041
LPL lipoprotein lipase 1.13041
GLUL glutamate-ammonia ligase 1.12872
S100A8 S100 calcium binding protein A8 1.12703
AR androgen receptor 1.12599
MET MET proto-oncogene, receptor tyrosine kinase 1.12357
ELF2 E74-like factor 2 (ets domain transcription factor) 1.11843
DDIT3 DNA-damage-inducible transcript 3 1.11775
INSIG2 insulin induced gene 2 1.11571
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.10977
COL11A1 collagen, type XI, alpha 1 1.10734
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.10699
NCL nucleolin 1.10699
SRXN1 sulfiredoxin 1 1.10596
VEGFA vascular endothelial growth factor A 1.09998
HMOX1 heme oxygenase 1 1.09963
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.09963
ACHE acetylcholinesterase (Yt blood group) 1.09681
BLVRB biliverdin reductase B 1.09011
BDNF brain-derived neurotrophic factor 1.08797
CCND2 cyclin D2 1.08301
ACTA1 actin, alpha 1, skeletal muscle 1.08231
MCM7 minichromosome maintenance complex component 7 1.08196
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.08161
E2F1 E2F transcription factor 1 1.08161
GAB2 GRB2-associated binding protein 2 1.07911
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 1.07911
IGFBP1 insulin-like growth factor binding protein 1 1.07875
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.07732
BMP7 bone morphogenetic protein 7 1.07447
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.07199
IGF1R insulin-like growth factor 1 receptor 1.06734
ACIN1 apoptotic chromatin condensation inducer 1 1.06734
TIMP2 TIMP metallopeptidase inhibitor 2 1.06625
FABP4 fatty acid binding protein 4, adipocyte 1.06588
CXCL2 chemokine (C-X-C motif) ligand 2 1.06261
MCC mutated in colorectal cancers 1.06188
S100A10 S100 calcium binding protein A10 1.06188
ASS1 argininosuccinate synthase 1 1.06152
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.05936
BCL2L1 BCL2-like 1 1.05936
PFDN5 prefoldin subunit 5 1.05648
TAT tyrosine aminotransferase 1.05498
TUBA1A tubulin, alpha 1a 1.05461
HAL histidine ammonia-lyase 1.05237
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.04831
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.04574
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.03789
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.03567
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.03456
RET ret proto-oncogene 1.03197
COL1A1 collagen, type I, alpha 1 1.03122
PRKCA protein kinase C, alpha 1.02933
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.02821
VLDLR very low density lipoprotein receptor 1.02522
CCNG2 cyclin G2 1.02336
GSTM1 glutathione S-transferase mu 1 1.0189
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.01776
UCK2 uridine-cytidine kinase 2 1.01739
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.01286
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.01286
CPD carboxypeptidase D 1.01286
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.01137
TSC22D3 TSC22 domain family, member 3 1.01137
GCLC glutamate-cysteine ligase, catalytic subunit 1.01062