Body Weight Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. (Experimental Factor Ontology, EFO_0004338)
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Genes

117 genes associated with the Body Weight phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
APOA2 apolipoprotein A-II
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AURKA aurora kinase A
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CALCR calcitonin receptor
CASR calcium-sensing receptor
CCK cholecystokinin
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CKM creatine kinase, muscle
CLOCK clock circadian regulator
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COMT catechol-O-methyltransferase
CRP C-reactive protein, pentraxin-related
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CTSK cathepsin K
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DGAT1 diacylglycerol O-acyltransferase 1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP1 fatty acid binding protein 1, liver
FABP2 fatty acid binding protein 2, intestinal
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HNF1A HNF1 homeobox A
HRH1 histamine receptor H1
HSPA1B heat shock 70kDa protein 1B
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INS insulin
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KLF2 Kruppel-like factor 2
LEP leptin
LEPR leptin receptor
LIPC lipase, hepatic
LIPE lipase, hormone-sensitive
LPL lipoprotein lipase
LRP5 low density lipoprotein receptor-related protein 5
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MT-TL1 tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCOA3 nuclear receptor coactivator 3
NDN necdin, melanoma antigen (MAGE) family member
NMB neuromedin B
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NR0B2 nuclear receptor subfamily 0, group B, member 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PGM1 phosphoglucomutase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLIN1 perilipin 1
PLXNA2 plexin A2
POMC proopiomelanocortin
PON1 paraoxonase 1
PON2 paraoxonase 2
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTH parathyroid hormone
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SOCS3 suppressor of cytokine signaling 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TH tyrosine hydroxylase
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TUB tubby bipartite transcription factor
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor