Bipolar disorder Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A mood disorder that involves alternating periods of mania and depression. (Human Disease Ontology, DOID_3312)
External Link https://www.ebi.ac.uk/gwas/search?query=Bipolar disorder
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Genes

55 genes associated with the Bipolar disorder phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.602611
LMAN2L lectin, mannose-binding 2-like 0.572839
TENM4 teneurin transmembrane protein 4 0.522843
NCAN neurocan 0.499091
PALB2 partner and localizer of BRCA2 0.439318
ADCY2 adenylate cyclase 2 (brain) 0.434785
DGKH diacylglycerol kinase, eta 0.405958
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.405958
MAU2 MAU2 sister chromatid cohesion factor 0.346786
MCTP1 multiple C2 domains, transmembrane 1 0.342586
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.314454
C11ORF80 chromosome 11 open reading frame 80 0.314454
NFIA nuclear factor I/A 0.295129
SYNE1 spectrin repeat containing, nuclear envelope 1 0.246511
LAMP3 lysosomal-associated membrane protein 3 0.246511
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.220915
TLE4 transducin-like enhancer of split 4 0.220915
CDC25B cell division cycle 25B 0.220915
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.220915
CTSF cathepsin F 0.220915
SLC35F4 solute carrier family 35, member F4 0.220915
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.165905
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.165905
TDRD9 tudor domain containing 9 0.165905
DPY19L3 dpy-19-like 3 (C. elegans) 0.165905
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 0.165905
ZNF490 zinc finger protein 490 0.165905
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.165905
GRIK5 glutamate receptor, ionotropic, kainate 5 0.165905
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.165905
RASIP1 Ras interacting protein 1 0.129504
KIAA1211L KIAA1211-like 0.129504
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.129504
FOXO6 forkhead box O6 0.129504
DLC1 DLC1 Rho GTPase activating protein 0.085234
ZNF385D zinc finger protein 385D 0.085234
AUTS2 autism susceptibility candidate 2 0.085234
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.085234
LOC102724845 0.085234
FAM189A2 family with sequence similarity 189, member A2 0.085234
TMEM63C transmembrane protein 63C 0.085234
NPAS3 neuronal PAS domain protein 3 0.085234
SIAE sialic acid acetylesterase 0.070053
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.070053
CAPN10-AS1 CAPN10 antisense RNA 1 (head to head) 0.070053
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 0.057619
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.057619
LOC101929118 0.057619
FAM126A family with sequence similarity 126, member A 0.048624
ZMIZ1 zinc finger, MIZ-type containing 1 0.048624
SLC45A4 solute carrier family 45, member 4 0.042592
CTSH cathepsin H 0.042592
CNTN1 contactin 1 0.042592
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 0.042592
DFNB31 deafness, autosomal recessive 31 0.042592