Bipolar Disorder Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description A mood disorder that involves alternating periods of mania and depression. (Human Disease Ontology, DOID_3312)
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Genes

102 genes associated with the trait Bipolar Disorder in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
LMAN2L lectin, mannose-binding 2-like 0.922056
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 0.907793
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.897125
NCAN neurocan 0.836775
PALB2 partner and localizer of BRCA2 0.769036
DGKH diacylglycerol kinase, eta 0.731179
FBLN1 fibulin 1 0.731179
INTS7 integrator complex subunit 7 0.731179
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.731179
TENM4 teneurin transmembrane protein 4 0.696869
MCTP1 multiple C2 domains, transmembrane 1 0.64828
DPY19L3 dpy-19-like 3 (C. elegans) 0.623513
C11ORF80 chromosome 11 open reading frame 80 0.609816
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.609816
LAMP3 lysosomal-associated membrane protein 3 0.527821
SYNE1 spectrin repeat containing, nuclear envelope 1 0.527821
TLE4 transducin-like enhancer of split 4 0.50084
DMTF1 cyclin D binding myb-like transcription factor 1 0.50084
CGNL1 cingulin-like 1 0.50084
CDC25B cell division cycle 25B 0.50084
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.50084
CTSF cathepsin F 0.50084
SLC35F4 solute carrier family 35, member F4 0.50084
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.50084
SGOL1 shugoshin-like 1 (S. pombe) 0.443956
GRIK5 glutamate receptor, ionotropic, kainate 5 0.443956
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 0.443956
TDRD9 tudor domain containing 9 0.443956
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.443956
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.443956
ZNF490 zinc finger protein 490 0.443956
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.443956
GPM6A glycoprotein M6A 0.443956
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.443956
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.443956
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.406869
RASIP1 Ras interacting protein 1 0.406869
FOXO6 forkhead box O6 0.406869
KIAA1211L KIAA1211-like 0.406869
PRSS3 protease, serine, 3 0.378873
BRWD1 bromodomain and WD repeat domain containing 1 0.378873
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.363583
ZNF385D zinc finger protein 385D 0.356676
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.356676
NPAS3 neuronal PAS domain protein 3 0.356676
MARCH5 membrane-associated ring finger (C3HC4) 5 0.34201
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.33862
SIAE sialic acid acetylesterase 0.33862
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.33862
C15ORF32 chromosome 15 open reading frame 32 0.33862
NCKAP5 NCK-associated protein 5 0.323808
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.323533
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 0.323533
KIAA0355 KIAA0355 0.323533
ZMIZ1 zinc finger, MIZ-type containing 1 0.310838
FAM126A family with sequence similarity 126, member A 0.310838
FAT4 FAT atypical cadherin 4 0.310838
WSCD2 WSC domain containing 2 0.310838
RGS5 regulator of G-protein signaling 5 0.301773
CTSH cathepsin H 0.29992
DFNB31 deafness, autosomal recessive 31 0.29992
VIPR1 vasoactive intestinal peptide receptor 1 0.273701
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.271553
VRK2 vaccinia related kinase 2 0.270155
ADAM19 ADAM metallopeptidase domain 19 0.249025
CENPO centromere protein O 0.247919
PTRHD1 peptidyl-tRNA hydrolase domain containing 1 0.247919
COL28A1 collagen, type XXVIII, alpha 1 0.240117
ZMAT4 zinc finger, matrin-type 4 0.228912
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.214803
IRF2 interferon regulatory factor 2 0.202915
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 0.202508
FANK1 fibronectin type III and ankyrin repeat domains 1 0.192538
UOX urate oxidase, pseudogene 0.191817
WWOX WW domain containing oxidoreductase 0.190394
CLSPN claspin 0.178845
FANCL Fanconi anemia, complementation group L 0.175313
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.16577
PTPRQ protein tyrosine phosphatase, receptor type, Q 0.165147
DMD dystrophin 0.157131
SPTBN1 spectrin, beta, non-erythrocytic 1 0.153239
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.142942
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 0.138146
AMPH amphiphysin 0.127587
COX20 COX20 cytochrome c oxidase assembly factor 0.11624
PCBP3 poly(rC) binding protein 3 0.097633
VGLL4 vestigial-like family member 4 0.096255
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.094729
CAMKMT calmodulin-lysine N-methyltransferase 0.0919
SMYD3 SET and MYND domain containing 3 0.09115
RPRD1B regulation of nuclear pre-mRNA domain containing 1B 0.08923
TBC1D15 TBC1 domain family, member 15 0.083449
TIAM2 T-cell lymphoma invasion and metastasis 2 0.080111
MAOB monoamine oxidase B 0.076028
ADRA1B adrenoceptor alpha 1B 0.074182
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.073818
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.071548
MAMDC2 MAM domain containing 2 0.067907
SMIM21 small integral membrane protein 21 0.064862
KIAA1033 KIAA1033 0.064774
NALCN sodium leak channel, non selective 0.064774
CNTNAP2 contactin associated protein-like 2 0.063991