Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-446193
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Genes

67 proteins participating in the Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway from the Reactome Pathways dataset.

Symbol Name
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG10 ALG10, alpha-1,2-glucosyltransferase
ALG10B ALG10B, alpha-1,2-glucosyltransferase
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
ALG9 ALG9, alpha-1,2-mannosyltransferase
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CTSA cathepsin A
DHDDS dehydrodolichyl diphosphate synthase
DOLK dolichol kinase
DOLPP1 dolichyldiphosphatase 1
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLB1 galactosidase, beta 1
GMPPA GDP-mannose pyrophosphorylase A
GMPPB GDP-mannose pyrophosphorylase B
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
MPDU1 mannose-P-dolichol utilization defect 1
MPI mannose phosphate isomerase
MVD mevalonate (diphospho) decarboxylase
NANP N-acetylneuraminic acid phosphatase
NANS N-acetylneuraminic acid synthase
NEU1 sialidase 1 (lysosomal sialidase)
NEU2 sialidase 2 (cytosolic sialidase)
NEU3 sialidase 3 (membrane sialidase)
NEU4 sialidase 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
PGM3 phosphoglucomutase 3
PMM1 phosphomannomutase 1
PMM2 phosphomannomutase 2
RFT1 RFT1 homolog (S. cerevisiae)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1