Back Pain Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the back. (Human Phenotype Ontology, HP_0003418)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D001416
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Genes

45 genes/proteins associated with the disease Back Pain from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
PLAT plasminogen activator, tissue 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.02252
TNF tumor necrosis factor 1.87825
BCL2 B-cell CLL/lymphoma 2 1.86706
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.6199
IL6 interleukin 6 1.60454
BAX BCL2-associated X protein 1.56239
CCL2 chemokine (C-C motif) ligand 2 1.55648
IL1B interleukin 1, beta 1.48505
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.42183
CAT catalase 1.40345
CYCS cytochrome c, somatic 1.36533
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.30421
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.29996
MAPK3 mitogen-activated protein kinase 3 1.28919
MAPK1 mitogen-activated protein kinase 1 1.27905
CXCL8 chemokine (C-X-C motif) ligand 8 1.27875
VCAM1 vascular cell adhesion molecule 1 1.26576
IL10 interleukin 10 1.24433
CCL3 chemokine (C-C motif) ligand 3 1.24275
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.23265
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.21271
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.20558
FOS FBJ murine osteosarcoma viral oncogene homolog 1.19213
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.16137
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.16104
SELL selectin L 1.14166
POR P450 (cytochrome) oxidoreductase 1.1294
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.12495
ICAM1 intercellular adhesion molecule 1 1.12357
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.11911
IL1A interleukin 1, alpha 1.11466
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.09892
MMP9 matrix metallopeptidase 9 1.09506
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.09011
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.08868
OPRK1 opioid receptor, kappa 1 1.08055
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.07589
TGFB1 transforming growth factor, beta 1 1.07553
VEGFA vascular endothelial growth factor A 1.04352
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.04163
CES2 carboxylesterase 2 1.02746
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.02559
RB1 retinoblastoma 1 1.01663
STMN1 stathmin 1 1.01249