BX-912 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

127 kinases inhibited by the BX-912 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
TAOK3 TAO kinase 3 1.36211
FLT4 fms-related tyrosine kinase 4 1.36211
ULK3 unc-51 like kinase 3 1.36211
ULK1 unc-51 like autophagy activating kinase 1 1.36211
NIM1K NIM1 serine/threonine protein kinase 1.36211
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.36211
RET ret proto-oncogene 1.36211
STK17A serine/threonine kinase 17a 1.35325
PRKX protein kinase, X-linked 1.35325
PTK2 protein tyrosine kinase 2 1.35325
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1.35325
EPHB6 EPH receptor B6 1.35325
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.35325
IRAK1 interleukin-1 receptor-associated kinase 1 1.34449
FGFR1 fibroblast growth factor receptor 1 1.34449
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.34449
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.34449
ULK2 unc-51 like autophagy activating kinase 2 1.34449
PKN1 protein kinase N1 1.34449
RIPK4 receptor-interacting serine-threonine kinase 4 1.34449
MARK3 MAP/microtubule affinity-regulating kinase 3 1.34449
TAOK1 TAO kinase 1 1.34449
SLK STE20-like kinase 1.33582
MARK2 MAP/microtubule affinity-regulating kinase 2 1.33582
CHEK1 checkpoint kinase 1 1.33582
SIK1 salt-inducible kinase 1 1.33582
MYLK2 myosin light chain kinase 2 1.33582
STK26 serine/threonine protein kinase 26 1.33582
NEK5 NIMA-related kinase 5 1.32726
RIOK3 RIO kinase 3 1.32726
STK3 serine/threonine kinase 3 1.32726
NEK6 NIMA-related kinase 6 1.32726
MARK1 MAP/microtubule affinity-regulating kinase 1 1.32726
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.32726
MAP3K9 mitogen-activated protein kinase kinase kinase 9 1.32726
NEK7 NIMA-related kinase 7 1.32726
MERTK MER proto-oncogene, tyrosine kinase 1.32726
STK16 serine/threonine kinase 16 1.31878
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.31878
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.31878
CDK7 cyclin-dependent kinase 7 1.31878
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.31878
BLK BLK proto-oncogene, Src family tyrosine kinase 1.31878
IRAK3 interleukin-1 receptor-associated kinase 3 1.3104
TBK1 TANK-binding kinase 1 1.3104
BMPR1B bone morphogenetic protein receptor, type IB 1.30212
STK33 serine/threonine kinase 33 1.30212
TNIK TRAF2 and NCK interacting kinase 1.30212
CIT citron rho-interacting serine/threonine kinase 1.30212
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.30212
SYK spleen tyrosine kinase 1.28583
SBK3 SH3 domain binding kinase family, member 3 1.28583
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.28583
FGFR3 fibroblast growth factor receptor 3 1.28583
AXL AXL receptor tyrosine kinase 1.26991
HIPK1 homeodomain interacting protein kinase 1 1.26991
DAPK1 death-associated protein kinase 1 1.26991
GAK cyclin G associated kinase 1.25436
TNK1 tyrosine kinase, non-receptor, 1 1.25436
CSF1R colony stimulating factor 1 receptor 1.25436
AURKA aurora kinase A 1.23916
HIPK2 homeodomain interacting protein kinase 2 1.23916
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 1.23916
MAPK15 mitogen-activated protein kinase 15 1.22432
CDKL5 cyclin-dependent kinase-like 5 1.22432
FGFR4 fibroblast growth factor receptor 4 1.22432
STK24 serine/threonine kinase 24 1.20983
HIPK4 homeodomain interacting protein kinase 4 1.20983
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.20983
MELK maternal embryonic leucine zipper kinase 1.19568
CLK2 CDC-like kinase 2 1.19568
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.19568
PHKG1 phosphorylase kinase, gamma 1 (muscle) 1.18873
PDPK1 3-phosphoinositide dependent protein kinase 1 1.18186
STK17B serine/threonine kinase 17b 1.18186
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.18186
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.16838
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 1.16838
AAK1 AP2 associated kinase 1 1.1361
STK11 serine/threonine kinase 11 1.12988
LCK LCK proto-oncogene, Src family tyrosine kinase 1.11767
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.11767
SBK1 SH3 domain binding kinase 1 1.10576
HIPK3 homeodomain interacting protein kinase 3 1.09992
NUAK2 NUAK family, SNF1-like kinase, 2 1.09415
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.08283
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.08283
DAPK3 death-associated protein kinase 3 1.08283
CHUK conserved helix-loop-helix ubiquitous kinase 1.07728
SRPK1 SRSF protein kinase 1 1.0718
MINK1 misshapen-like kinase 1 1.0718
ANKK1 ankyrin repeat and kinase domain containing 1 1.06639
MET MET proto-oncogene, receptor tyrosine kinase 1.06105
ITK IL2-inducible T-cell kinase 1.05577
NEK9 NIMA-related kinase 9 1.05057
PKN2 protein kinase N2 1.05057
FGFR2 fibroblast growth factor receptor 2 1.05057
CAMK1D calcium/calmodulin-dependent protein kinase ID 1.05057
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.05057
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.04543
INSRR insulin receptor-related receptor 1.04035
ACVR2B activin A receptor, type IIB 1.03535
TTK TTK protein kinase 1.03041
BTK Bruton agammaglobulinemia tyrosine kinase 1.02071
TAOK2 TAO kinase 2 1.01596
PRPF4B pre-mRNA processing factor 4B 1.01596
SRPK2 SRSF protein kinase 2 1.01127
GRK4 G protein-coupled receptor kinase 4 1.00208
BRSK2 BR serine/threonine kinase 2 0.993117
SRPK3 SRSF protein kinase 3 0.975893
NEK2 NIMA-related kinase 2 0.975893
ACVR2A activin A receptor, type IIA 0.967615
MYLK4 myosin light chain kinase family, member 4 0.9517
SIK3 SIK family kinase 3 0.944052
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.940302
BRSK1 BR serine/threonine kinase 1 0.922275
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.915387
SIK2 salt-inducible kinase 2 0.908676
FYN FYN proto-oncogene, Src family tyrosine kinase 0.902136
PTK2B protein tyrosine kinase 2 beta 0.902136
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.895762
PHKG2 phosphorylase kinase, gamma 2 (testis) 0.880521
DMPK dystrophia myotonica-protein kinase 0.874689
MUSK muscle, skeletal, receptor tyrosine kinase 0.866209
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.860727
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.852752
ICK intestinal cell (MAK-like) kinase 0.850157