BUB1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description BUB1 mitotic checkpoint serine/threonine kinase|This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 699)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BUB1
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Genes

69 co-expressed genes for BUB1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ASF1B anti-silencing function 1B histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
AURKB aurora kinase B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CCNB1 cyclin B1
CCNB2 cyclin B2
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CDC20 cell division cycle 20
CDCA8 cell division cycle associated 8
CDT1 chromatin licensing and DNA replication factor 1
CENPE centromere protein E, 312kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CKS1B CDC28 protein kinase regulatory subunit 1B
CYCS cytochrome c, somatic
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EI24 etoposide induced 2.4
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FOXM1 forkhead box M1
GARS glycyl-tRNA synthetase
GMNN geminin, DNA replication inhibitor
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
H2AFZ H2A histone family, member Z
HAT1 histone acetyltransferase 1
HDAC2 histone deacetylase 2
HDDC2 HD domain containing 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
IARS isoleucyl-tRNA synthetase
IMMT inner membrane protein, mitochondrial
KHSRP KH-type splicing regulatory protein
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MELK maternal embryonic leucine zipper kinase
MFAP1 microfibrillar-associated protein 1
MRPS18B mitochondrial ribosomal protein S18B
NDC80 NDC80 kinetochore complex component
NUDC nudC nuclear distribution protein
PLK1 polo-like kinase 1
PMEL premelanosome protein
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
RANBP1 RAN binding protein 1
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SMC2 structural maintenance of chromosomes 2
SPAG5 sperm associated antigen 5
SRPK1 SRSF protein kinase 1
SRSF1 serine/arginine-rich splicing factor 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
TARS threonyl-tRNA synthetase
TFDP1 transcription factor Dp-1
TPX2 TPX2, microtubule-associated
TYRO3 TYRO3 protein tyrosine kinase
USP1 ubiquitin specific peptidase 1
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase
ZWINT ZW10 interacting kinetochore protein