BTK Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description Bruton agammaglobulinemia tyrosine kinase|The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 695)
External Link http://www.ncbi.nlm.nih.gov/gene/695
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Genes

10 substrates of the kinase BTK from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
BMX BMX non-receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
GTF2I general transcription factor IIi
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITK IL2-inducible T-cell kinase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
STAT5A signal transducer and activator of transcription 5A
TEC tec protein tyrosine kinase
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein