BRD-U94846492_Quinine hemisulfate salt monohydrate_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-U94846492_Quinine hemisulfate salt monohydrate_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CA2 carbonic anhydrase II
CX3CR1 chemokine (C-X3-C motif) receptor 1
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HN1 hematological and neurological expressed 1
IFI44L interferon-induced protein 44-like
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MX1 MX dynamin-like GTPase 1
NAMPT nicotinamide phosphoribosyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
PDZK1 PDZ domain containing 1
SCG5 secretogranin V
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TGFBI transforming growth factor, beta-induced, 68kDa
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ALAS1 5'-aminolevulinate synthase 1
AMIGO2 adhesion molecule with Ig-like domain 2
CADM1 cell adhesion molecule 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DPYSL3 dihydropyrimidinase-like 3
FBLN1 fibulin 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1