BRD-U82589721_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-U82589721_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL5 chemokine (C-C motif) ligand 5
CD163 CD163 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CHN2 chimerin 2
CLIC5 chloride intracellular channel 5
CLU clusterin
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
E2F2 E2F transcription factor 2
EGR1 early growth response 1
EREG epiregulin
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
IDO1 indoleamine 2,3-dioxygenase 1
IFITM1 interferon induced transmembrane protein 1
IL2RA interleukin 2 receptor, alpha
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0226L KIAA0226-like
LAMP1 lysosomal-associated membrane protein 1
LDHB lactate dehydrogenase B
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTS neurotensin
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PLAU plasminogen activator, urokinase
RUNX3 runt-related transcription factor 3
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UPK1B uroplakin 1B
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ANXA4 annexin A4
BEX1 brain expressed, X-linked 1
C2CD5 C2 calcium-dependent domain containing 5
CCNF cyclin F
CDC20 cell division cycle 20
EIF5 eukaryotic translation initiation factor 5
GLRX glutaredoxin (thioltransferase)
H2AFX H2A histone family, member X
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IER3 immediate early response 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLJ3 immunoglobulin lambda joining 3
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KDM3A lysine (K)-specific demethylase 3A
MARCKSL1 MARCKS-like 1
MAT2A methionine adenosyltransferase II, alpha
MMP7 matrix metallopeptidase 7
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
PLK1 polo-like kinase 1
PROM1 prominin 1
RRM2 ribonucleotide reductase M2
S100A7 S100 calcium binding protein A7
SOX4 SRY (sex determining region Y)-box 4
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TBC1D4 TBC1 domain family, member 4
TBP TATA box binding protein
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb