BRD-U64521890_XMD16-144_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-U64521890_XMD16-144_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
BEX1 brain expressed, X-linked 1
CCL2 chemokine (C-C motif) ligand 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CHGB chromogranin B
DACH1 dachshund family transcription factor 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EFHD1 EF-hand domain family, member D1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGFBP5 insulin-like growth factor binding protein 5
LMO3 LIM domain only 3 (rhombotin-like 2)
LPIN1 lipin 1
MCL1 myeloid cell leukemia 1
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
NEFL neurofilament, light polypeptide
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
OLFM1 olfactomedin 1
PCDH9 protocadherin 9
PCP4 Purkinje cell protein 4
PF4 platelet factor 4
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS4 regulator of G-protein signaling 4
SCG5 secretogranin V
SCRG1 stimulator of chondrogenesis 1
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
STMN2 stathmin 2
SV2B synaptic vesicle glycoprotein 2B
SYT1 synaptotagmin I
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TP53I3 tumor protein p53 inducible protein 3
TPD52L1 tumor protein D52-like 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VNN1 vanin 1
VSNL1 visinin-like 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
ASPN asporin
C3 complement component 3
CA12 carbonic anhydrase XII
CAB39 calcium binding protein 39
CCND2 cyclin D2
CD44 CD44 molecule (Indian blood group)
COL4A2 collagen, type IV, alpha 2
COL6A2 collagen, type VI, alpha 2
CYCS cytochrome c, somatic
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCT dopachrome tautomerase
F2RL1 coagulation factor II (thrombin) receptor-like 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GUSBP3 glucuronidase, beta pseudogene 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL7R interleukin 7 receptor
JADE2 jade family PHD finger 2
KRT8 keratin 8, type II
MBP myelin basic protein
MLANA melan-A
MPO myeloperoxidase
NID2 nidogen 2 (osteonidogen)
PITX1 paired-like homeodomain 1
PLN phospholamban
PMEL premelanosome protein
PROM1 prominin 1
RUNX3 runt-related transcription factor 3
S100A4 S100 calcium binding protein A4
SCGB2A1 secretoglobin, family 2A, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TRIP6 thyroid hormone receptor interactor 6
TYRP1 tyrosinase-related protein 1