BRD-U64521890_XMD16-144_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-U64521890_XMD16-144_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCHE butyrylcholinesterase
BID BH3 interacting domain death agonist
BPHL biphenyl hydrolase-like (serine hydrolase)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
DCN decorin
DPP4 dipeptidyl-peptidase 4
GDF15 growth differentiation factor 15
GLO1 glyoxalase I
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HNMT histamine N-methyltransferase
HSPA1A heat shock 70kDa protein 1A
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG3 paternally expressed 3
PPAP2B phosphatidic acid phosphatase type 2B
RGS2 regulator of G-protein signaling 2
SDC2 syndecan 2
SPP1 secreted phosphoprotein 1
SRPX sushi-repeat containing protein, X-linked
TIMP3 TIMP metallopeptidase inhibitor 3
TUBB2A tubulin, beta 2A class IIa
USP18 ubiquitin specific peptidase 18

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
AURKA aurora kinase A
DUSP3 dual specificity phosphatase 3
EREG epiregulin
HMOX1 heme oxygenase 1
IL1R2 interleukin 1 receptor, type II
JAG1 jagged 1
JMJD6 jumonji domain containing 6
KRT14 keratin 14, type I
LY75 lymphocyte antigen 75
MET MET proto-oncogene, receptor tyrosine kinase
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIP prolactin-induced protein
RBPMS RNA binding protein with multiple splicing
SFRP1 secreted frizzled-related protein 1
TAGLN2 transgelin 2
TKT transketolase
TM4SF1 transmembrane 4 L six family member 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZFP36L2 ZFP36 ring finger protein-like 2