BRD-U64521890_XMD16-144_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

156 genes differentially expressed following the BRD-U64521890_XMD16-144_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACOT7 acyl-CoA thioesterase 7
ACSL3 acyl-CoA synthetase long-chain family member 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BEX1 brain expressed, X-linked 1
CD24 CD24 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLGN calmegin
COL2A1 collagen, type II, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB1 cAMP responsive element binding protein 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DSP desmoplakin
EFNB2 ephrin-B2
EMX2 empty spiracles homeobox 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPHA3 EPH receptor A3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL1 four and a half LIM domains 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HSPA1A heat shock 70kDa protein 1A
IFI6 interferon, alpha-inducible protein 6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JAG1 jagged 1
KIF2C kinesin family member 2C
KLF4 Kruppel-like factor 4 (gut)
LAMP2 lysosomal-associated membrane protein 2
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MAB21L2 mab-21-like 2 (C. elegans)
MAP1A microtubule-associated protein 1A
MOXD1 monooxygenase, DBH-like 1
MYO1B myosin IB
NTS neurotensin
ODC1 ornithine decarboxylase 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PBX3 pre-B-cell leukemia homeobox 3
PCDH9 protocadherin 9
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PPAP2B phosphatidic acid phosphatase type 2B
PRUNE2 prune homolog 2 (Drosophila)
RPS4Y1 ribosomal protein S4, Y-linked 1
RRBP1 ribosome binding protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SOX9 SRY (sex determining region Y)-box 9
STK38L serine/threonine kinase 38 like
STXBP1 syntaxin binding protein 1
TARP TCR gamma alternate reading frame protein
TMSB15A thymosin beta 15a
TOB1 transducer of ERBB2, 1
TST thiosulfate sulfurtransferase (rhodanese)
TUBB4B tubulin, beta 4B class IVb
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
APOE apolipoprotein E
BST2 bone marrow stromal cell antigen 2
CD200 CD200 molecule
CDC25A cell division cycle 25A
CDK4 cyclin-dependent kinase 4
COL4A2 collagen, type IV, alpha 2
CRYAB crystallin, alpha B
DDIT4 DNA-damage-inducible transcript 4
DPYD dihydropyrimidine dehydrogenase
EFHD1 EF-hand domain family, member D1
EFS embryonal Fyn-associated substrate
FAM57A family with sequence similarity 57, member A
FXYD5 FXYD domain containing ion transport regulator 5
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HOXB2 homeobox B2
IFI16 interferon, gamma-inducible protein 16
IGFBP4 insulin-like growth factor binding protein 4
IL18 interleukin 18
IL6ST interleukin 6 signal transducer
ITM2A integral membrane protein 2A
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0101 KIAA0101
KLK10 kallikrein-related peptidase 10
KRT15 keratin 15, type I
KRT7 keratin 7, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIMCH1 LIM and calponin homology domains 1
LOC100505650 uncharacterized LOC100505650
LY6E lymphocyte antigen 6 complex, locus E
MCM2 minichromosome maintenance complex component 2
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MDK midkine (neurite growth-promoting factor 2)
MPO myeloperoxidase
NDRG2 NDRG family member 2
NID1 nidogen 1
NMI N-myc (and STAT) interactor
OLFML2A olfactomedin-like 2A
OLFML3 olfactomedin-like 3
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PDZK1IP1 PDZK1 interacting protein 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIP prolactin-induced protein
PLA2G16 phospholipase A2, group XVI
PLAT plasminogen activator, tissue
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRKCD protein kinase C, delta
PROM1 prominin 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBPMS RNA binding protein with multiple splicing
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SCG5 secretogranin V
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS3 sorbin and SH3 domain containing 3
SPP1 secreted phosphoprotein 1
TFPI2 tissue factor pathway inhibitor 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TM4SF1 transmembrane 4 L six family member 1
TNS3 tensin 3
TPM1 tropomyosin 1 (alpha)
TPM4 tropomyosin 4
TRIP6 thyroid hormone receptor interactor 6
TUSC3 tumor suppressor candidate 3
UPP1 uridine phosphorylase 1
VCAN versican
VGLL1 vestigial-like family member 1
XBP1 X-box binding protein 1
ZBED2 zinc finger, BED-type containing 2
ZFP36L1 ZFP36 ring finger protein-like 1