BRD-U61997977_WZ-4-145_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the BRD-U61997977_WZ-4-145_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
CD44 CD44 molecule (Indian blood group)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COLEC12 collectin sub-family member 12
EMX2 empty spiracles homeobox 2
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
GSN gelsolin
IGL immunoglobulin lambda locus
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MANSC1 MANSC domain containing 1
NAV2 neuron navigator 2
PBX1 pre-B-cell leukemia homeobox 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLIN2 perilipin 2
PRUNE2 prune homolog 2 (Drosophila)
RGS1 regulator of G-protein signaling 1
SESN1 sestrin 1
SLC38A1 solute carrier family 38, member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRPX sushi-repeat containing protein, X-linked
SYNJ2 synaptojanin 2
TRIP6 thyroid hormone receptor interactor 6
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CD1E CD1e molecule
CDC25A cell division cycle 25A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHGB chromogranin B
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP4 dual specificity phosphatase 4
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
LEF1 lymphoid enhancer-binding factor 1
MYL1 myosin, light chain 1, alkali; skeletal, fast
NRIP1 nuclear receptor interacting protein 1
PDLIM3 PDZ and LIM domain 3
S100P S100 calcium binding protein P
SOX9 SRY (sex determining region Y)-box 9
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)