BRD-U61997977_WZ-4-145_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-U61997977_WZ-4-145_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADD3 adducin 3 (gamma)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
BLVRB biliverdin reductase B
C10ORF10 chromosome 10 open reading frame 10
C3 complement component 3
CBR3 carbonyl reductase 3
CD163 CD163 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLU clusterin
CXCL12 chemokine (C-X-C motif) ligand 12
DEFB1 defensin, beta 1
F13A1 coagulation factor XIII, A1 polypeptide
FAM107A family with sequence similarity 107, member A
FOXN3 forkhead box N3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPX3 glutathione peroxidase 3
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KRT19 keratin 19, type I
MAN1A1 mannosidase, alpha, class 1A, member 1
MDFIC MyoD family inhibitor domain containing
METTL7A methyltransferase like 7A
MMP7 matrix metallopeptidase 7
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
NNMT nicotinamide N-methyltransferase
NUPR1 nuclear protein, transcriptional regulator, 1
PDGFD platelet derived growth factor D
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROM1 prominin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SGCE sarcoglycan, epsilon
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLPI secretory leukocyte peptidase inhibitor
SPINK1 serine peptidase inhibitor, Kazal type 1
SUN1 Sad1 and UNC84 domain containing 1
TSC22D3 TSC22 domain family, member 3
TWIST1 twist family bHLH transcription factor 1
VGLL1 vestigial-like family member 1
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ATP9A ATPase, class II, type 9A
CCL20 chemokine (C-C motif) ligand 20
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCNE2 cyclin E2
CD8A CD8a molecule
CD9 CD9 molecule
CDC25A cell division cycle 25A
CST7 cystatin F (leukocystatin)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DEGS1 delta(4)-desaturase, sphingolipid 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGR3 early growth response 3
EHD1 EH-domain containing 1
FOSL1 FOS-like antigen 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMK granzyme K (granzyme 3; tryptase II)
HBEGF heparin-binding EGF-like growth factor
HMGA2 high mobility group AT-hook 2
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IGHM immunoglobulin heavy constant mu
IGLV3-19 immunoglobulin lambda variable 3-19
IL1B interleukin 1, beta
ITGA6 integrin, alpha 6
LIF leukemia inhibitory factor
MAP2K3 mitogen-activated protein kinase kinase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
OSBPL10 oxysterol binding protein-like 10
PFKP phosphofructokinase, platelet
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SLCO4A1 solute carrier organic anion transporter family, member 4A1
TCL1A T-cell leukemia/lymphoma 1A
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TGM2 transglutaminase 2
THBD thrombomodulin
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TXNDC9 thioredoxin domain containing 9