BRD-U60236422_WH-4-025_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-U60236422_WH-4-025_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND2 cyclin D2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CSTA cystatin A (stefin A)
CXCL5 chemokine (C-X-C motif) ligand 5
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HMG20B high mobility group 20B
JADE2 jade family PHD finger 2
KRT17 keratin 17, type I
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA4 melanoma antigen family A4
MAGEA6 melanoma antigen family A6
MECOM MDS1 and EVI1 complex locus
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RXRA retinoid X receptor, alpha
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
STAB1 stabilin 1
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ALCAM activated leukocyte cell adhesion molecule
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCND1 cyclin D1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEMIP cell migration inducing protein, hyaluronan binding
CHMP2B charged multivesicular body protein 2B
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EGR3 early growth response 3
ELOVL5 ELOVL fatty acid elongase 5
EREG epiregulin
FOSL1 FOS-like antigen 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HDAC9 histone deacetylase 9
IER3 immediate early response 3
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
MAP1B microtubule-associated protein 1B
MYC v-myc avian myelocytomatosis viral oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCP4 Purkinje cell protein 4
PIP prolactin-induced protein
RND3 Rho family GTPase 3
RRM2 ribonucleotide reductase M2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC38A1 solute carrier family 38, member 1
SOX4 SRY (sex determining region Y)-box 4
STC2 stanniocalcin 2
SULF1 sulfatase 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TUFT1 tuftelin 1
UGCG UDP-glucose ceramide glucosyltransferase