BRD-U51024685_HG-6-64-01_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-U51024685_HG-6-64-01_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
CAV1 caveolin 1, caveolae protein, 22kDa
CD52 CD52 molecule
CERS6 ceramide synthase 6
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL13 chemokine (C-X-C motif) ligand 13
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
DPT dermatopontin
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FAM129A family with sequence similarity 129, member A
FBN1 fibrillin 1
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
GREM1 gremlin 1, DAN family BMP antagonist
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGL immunoglobulin lambda locus
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
LOX lysyl oxidase
NARFL nuclear prelamin A recognition factor-like
PEG10 paternally expressed 10
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRKCB protein kinase C, beta
PSAT1 phosphoserine aminotransferase 1
RAB2A RAB2A, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SOX4 SRY (sex determining region Y)-box 4
TOB1 transducer of ERBB2, 1
TSC22D3 TSC22 domain family, member 3
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AKAP12 A kinase (PRKA) anchor protein 12
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
CCND1 cyclin D1
COLEC12 collectin sub-family member 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DACH1 dachshund family transcription factor 1
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EGR3 early growth response 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBB hemoglobin, beta
HMGA2 high mobility group AT-hook 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
JUN jun proto-oncogene
KRT5 keratin 5, type II
LAMA3 laminin, alpha 3
LAMP5 lysosomal-associated membrane protein family, member 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MGP matrix Gla protein
MSMB microseminoprotein, beta-
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEBL nebulette
NEFL neurofilament, light polypeptide
NGRN neugrin, neurite outgrowth associated
NPTX2 neuronal pentraxin II
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLIN2 perilipin 2
RGS4 regulator of G-protein signaling 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAP25 synaptosomal-associated protein, 25kDa
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SYT1 synaptotagmin I
TARP TCR gamma alternate reading frame protein
TF transferrin
TFF1 trefoil factor 1
TGFA transforming growth factor, alpha
TGM4 transglutaminase 4
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C