BRD-M86331534_BJM-ctd2-9_THP1_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

159 genes differentially expressed following the BRD-M86331534_BJM-ctd2-9_THP1_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD10 ankyrin repeat domain 10
ARHGAP29 Rho GTPase activating protein 29
ARMCX1 armadillo repeat containing, X-linked 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
BTG3 BTG family, member 3
C10ORF10 chromosome 10 open reading frame 10
CBS cystathionine-beta-synthase
CCNG2 cyclin G2
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A2 collagen, type I, alpha 2
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CTNND1 catenin (cadherin-associated protein), delta 1
CXADR coxsackie virus and adenovirus receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DPP4 dipeptidyl-peptidase 4
DST dystonin
DUSP4 dual specificity phosphatase 4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EXT1 exostosin glycosyltransferase 1
FOLR1 folate receptor 1 (adult)
FZD7 frizzled class receptor 7
GAGE3 G antigen 3
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KIAA0907 KIAA0907
KLK5 kallikrein-related peptidase 5
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
MAPT microtubule-associated protein tau
MEIS2 Meis homeobox 2
MXI1 MAX interactor 1, dimerization protein
MYO6 myosin VI
NFIL3 nuclear factor, interleukin 3 regulated
NOV nephroblastoma overexpressed
NT5E 5'-nucleotidase, ecto (CD73)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
P3H2 prolyl 3-hydroxylase 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNISR PNN-interacting serine/arginine-rich protein
PPOX protoporphyrinogen oxidase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRPF4B pre-mRNA processing factor 4B
PSAT1 phosphoserine aminotransferase 1
PTN pleiotrophin
PTPRO protein tyrosine phosphatase, receptor type, O
RAD51AP1 RAD51 associated protein 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SHB Src homology 2 domain containing adaptor protein B
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SOX9 SRY (sex determining region Y)-box 9
SRRM2 serine/arginine repetitive matrix 2
SSPN sarcospan
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
TBX3 T-box 3
TFRC transferrin receptor
TMEM45A transmembrane protein 45A
TMSB15A thymosin beta 15a
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
XBP1 X-box binding protein 1
ZNF395 zinc finger protein 395
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ASCC3 activating signal cointegrator 1 complex subunit 3
ASXL2 additional sex combs like transcriptional regulator 2
AURKA aurora kinase A
AZU1 azurocidin 1
BASP1 brain abundant, membrane attached signal protein 1
CCNF cyclin F
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CLEC11A C-type lectin domain family 11, member A
COG2 component of oligomeric golgi complex 2
CPVL carboxypeptidase, vitellogenic-like
CYBA cytochrome b-245, alpha polypeptide
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM98A family with sequence similarity 98, member A
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GRWD1 glutamate-rich WD repeat containing 1
IGF1R insulin-like growth factor 1 receptor
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IRS2 insulin receptor substrate 2
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
MAGED1 melanoma antigen family D1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NR2F2 nuclear receptor subfamily 2, group F, member 2
PCTP phosphatidylcholine transfer protein
PCYOX1L prenylcysteine oxidase 1 like
PLAC8 placenta-specific 8
PLIN3 perilipin 3
PLK1 polo-like kinase 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTTG1 pituitary tumor-transforming 1
S100P S100 calcium binding protein P
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMA4 glucuronidase, beta pseudogene
SMCO4 single-pass membrane protein with coiled-coil domains 4
SORD sorbitol dehydrogenase
TEX10 testis expressed 10
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK2 tousled-like kinase 2
TMEM109 transmembrane protein 109
TPX2 TPX2, microtubule-associated
TRIM14 tripartite motif containing 14
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TUBD1 tubulin, delta 1
ZNF652 zinc finger protein 652