BRD-M86331534_BJM-ctd2-9_HCT116_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

233 genes differentially expressed following the BRD-M86331534_BJM-ctd2-9_HCT116_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADM adrenomedullin
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
APLP2 amyloid beta (A4) precursor-like protein 2
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
BTG3 BTG family, member 3
C3ORF14 chromosome 3 open reading frame 14
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CARS cysteinyl-tRNA synthetase
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLC Charcot-Leyden crystal galectin
CLDND1 claudin domain containing 1
CLIC4 chloride intracellular channel 4
COL15A1 collagen, type XV, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DRAM1 DNA-damage regulated autophagy modulator 1
DSG3 desmoglein 3
DSP desmoplakin
DST dystonin
DUSP1 dual specificity phosphatase 1
DUSP14 dual specificity phosphatase 14
DUSP4 dual specificity phosphatase 4
DYNLT3 dynein, light chain, Tctex-type 3
EAPP E2F-associated phosphoprotein
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR2 early growth response 2
EMP1 epithelial membrane protein 1
EPRS glutamyl-prolyl-tRNA synthetase
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FA2H fatty acid 2-hydroxylase
FAS Fas cell surface death receptor
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FHL2 four and a half LIM domains 2
FLNB filamin B, beta
FNTA farnesyltransferase, CAAX box, alpha
FXYD3 FXYD domain containing ion transport regulator 3
FZD6 frizzled class receptor 6
GADD45A growth arrest and DNA-damage-inducible, alpha
GARS glycyl-tRNA synthetase
GATA3 GATA binding protein 3
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GOLGA8B golgin A8 family, member B
GOLT1B golgi transport 1B
GPRC5A G protein-coupled receptor, class C, group 5, member A
GREM1 gremlin 1, DAN family BMP antagonist
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA13 heat shock protein 70kDa family, member 13
IARS isoleucyl-tRNA synthetase
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
INPP1 inositol polyphosphate-1-phosphatase
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT23 keratin 23, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
KRT81 keratin 81, type II
LAMP3 lysosomal-associated membrane protein 3
LMO4 LIM domain only 4
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MARS methionyl-tRNA synthetase
MCL1 myeloid cell leukemia 1
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
N4BP2L2 NEDD4 binding protein 2-like 2
NAP1L1 nucleosome assembly protein 1-like 1
NCF2 neutrophil cytosolic factor 2
NCOA4 nuclear receptor coactivator 4
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OLFM4 olfactomedin 4
OPN3 opsin 3
PALLD palladin, cytoskeletal associated protein
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAGL1 pleiomorphic adenoma gene-like 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RIOK3 RIO kinase 3
RPS27L ribosomal protein S27-like
RSL24D1 ribosomal L24 domain containing 1
S100A12 S100 calcium binding protein A12
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SARS seryl-tRNA synthetase
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERINC1 serine incorporator 1
SERINC5 serine incorporator 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
SH3GLB1 SH3-domain GRB2-like endophilin B1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAI2 snail family zinc finger 2
SOCS2 suppressor of cytokine signaling 2
SPRR1B small proline-rich protein 1B
SRGN serglycin
STAR steroidogenic acute regulatory protein
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TARS threonyl-tRNA synthetase
TCL1A T-cell leukemia/lymphoma 1A
TERF2IP telomeric repeat binding factor 2, interacting protein
TGFA transforming growth factor, alpha
TGFBI transforming growth factor, beta-induced, 68kDa
TJP1 tight junction protein 1
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM123 transmembrane protein 123
TMEM45A transmembrane protein 45A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPD52 tumor protein D52
TRIM22 tripartite motif containing 22
TUFT1 tuftelin 1
TXNRD1 thioredoxin reductase 1
UBE2A ubiquitin-conjugating enzyme E2A
UFM1 ubiquitin-fold modifier 1
VIM vimentin
WARS tryptophanyl-tRNA synthetase
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
AURKA aurora kinase A
BCHE butyrylcholinesterase
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CCNF cyclin F
CDC25B cell division cycle 25B
CENPA centromere protein A
CLU clusterin
COA3 cytochrome c oxidase assembly factor 3
CP ceruloplasmin (ferroxidase)
CPNE1 copine I
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYTL1 cytokine-like 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FAM46C family with sequence similarity 46, member C
FAM64A family with sequence similarity 64, member A
FRZB frizzled-related protein
GNPDA1 glucosamine-6-phosphate deaminase 1
GPRC5B G protein-coupled receptor, class C, group 5, member B
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HSPA8 heat shock 70kDa protein 8
ITM2A integral membrane protein 2A
JMJD6 jumonji domain containing 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF20A kinesin family member 20A
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPL lipoprotein lipase
LPP LIM domain containing preferred translocation partner in lipoma
MAST2 microtubule associated serine/threonine kinase 2
NELL2 NEL-like 2 (chicken)
OLFM1 olfactomedin 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLK1 polo-like kinase 1
PLTP phospholipid transfer protein
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
QPRT quinolinate phosphoribosyltransferase
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
TBC1D16 TBC1 domain family, member 16
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM14 tripartite motif containing 14
TSPAN4 tetraspanin 4
UBE2C ubiquitin-conjugating enzyme E2C