BRD-K99818283_PIK-90_RMGI_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

154 genes differentially expressed following the BRD-K99818283_PIK-90_RMGI_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ANG angiogenin, ribonuclease, RNase A family, 5
ARMCX6 armadillo repeat containing, X-linked 6
BBX bobby sox homolog (Drosophila)
BRCA1 breast cancer 1, early onset
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFD complement factor D (adipsin)
CLU clusterin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST3 cystatin C
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
DEGS1 delta(4)-desaturase, sphingolipid 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM134B family with sequence similarity 134, member B
FAXDC2 fatty acid hydroxylase domain containing 2
FGFR1 fibroblast growth factor receptor 1
FOXO1 forkhead box O1
GABARAPL1 GABA(A) receptor-associated protein like 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
HBP1 HMG-box transcription factor 1
HMG20B high mobility group 20B
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI16 interferon, gamma-inducible protein 16
IGF1R insulin-like growth factor 1 receptor
ITM2A integral membrane protein 2A
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCTD12 potassium channel tetramerization domain containing 12
LHFPL2 lipoma HMGIC fusion partner-like 2
LTF lactotransferrin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MBNL1 muscleblind-like splicing regulator 1
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
MSN moesin
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MTUS1 microtubule associated tumor suppressor 1
NCOA3 nuclear receptor coactivator 3
NFIL3 nuclear factor, interleukin 3 regulated
PECAM1 platelet/endothelial cell adhesion molecule 1
PIR pirin (iron-binding nuclear protein)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RB1CC1 RB1-inducible coiled-coil 1
RNASE4 ribonuclease, RNase A family, 4
RNF13 ring finger protein 13
SEPP1 selenoprotein P, plasma, 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
STAG2 stromal antigen 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TMEM106B transmembrane protein 106B
TRBC1 T cell receptor beta constant 1
TXNIP thioredoxin interacting protein
WDTC1 WD and tetratricopeptide repeats 1
ZBTB16 zinc finger and BTB domain containing 16
ZKSCAN1 zinc finger with KRAB and SCAN domains 1

decreased expression

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
AQP3 aquaporin 3 (Gill blood group)
AUTS2 autism susceptibility candidate 2
BAALC brain and acute leukemia, cytoplasmic
CAPN2 calpain 2, (m/II) large subunit
CCND1 cyclin D1
CD200 CD200 molecule
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNPY3 canopy FGF signaling regulator 3
CRISP3 cysteine-rich secretory protein 3
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EDNRA endothelin receptor type A
EMP1 epithelial membrane protein 1
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRWD1 glutamate-rich WD repeat containing 1
HBB hemoglobin, beta
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HMGA2 high mobility group AT-hook 2
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1RN interleukin 1 receptor antagonist
INHBA inhibin, beta A
INHBB inhibin, beta B
KAZN kazrin, periplakin interacting protein
KLK10 kallikrein-related peptidase 10
KRT4 keratin 4, type II
KRT6A keratin 6A, type II
KRT7 keratin 7, type II
LAMA3 laminin, alpha 3
LAMC2 laminin, gamma 2
LAMP5 lysosomal-associated membrane protein family, member 5
LCN2 lipocalin 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MMP7 matrix metallopeptidase 7
MOXD1 monooxygenase, DBH-like 1
MSLN mesothelin
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
PAM peptidylglycine alpha-amidating monooxygenase
PFKP phosphofructokinase, platelet
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
PNN pinin, desmosome associated protein
PPIF peptidylprolyl isomerase F
RGS1 regulator of G-protein signaling 1
RPL37A ribosomal protein L37a
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SCEL sciellin
SDC1 syndecan 1
SERHL2 serine hydrolase-like 2
SFN stratifin
SHB Src homology 2 domain containing adaptor protein B
SLPI secretory leukocyte peptidase inhibitor
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D31 TBC1 domain family, member 31
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFRC transferrin receptor
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TP53BP2 tumor protein p53 binding protein 2
UBE3C ubiquitin protein ligase E3C
VCAN versican