BRD-K99818283_PIK-90_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K99818283_PIK-90_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA4 annexin A4
ATP9A ATPase, class II, type 9A
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
C6ORF62 chromosome 6 open reading frame 62
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CPM carboxypeptidase M
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
EDN1 endothelin 1
EFNA1 ephrin-A1
ERBB3 erb-b2 receptor tyrosine kinase 3
FOXO4 forkhead box O4
GABARAPL1 GABA(A) receptor-associated protein like 1
GPR137B G protein-coupled receptor 137B
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBP1 HMG-box transcription factor 1
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
LCN2 lipocalin 2
MAN1A1 mannosidase, alpha, class 1A, member 1
MGLL monoglyceride lipase
MTMR11 myotubularin related protein 11
MXI1 MAX interactor 1, dimerization protein
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
RAB40B RAB40B, member RAS oncogene family
SH3BGRL SH3 domain binding glutamate-rich protein like
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
TNS1 tensin 1
TXNIP thioredoxin interacting protein
WDTC1 WD and tetratricopeptide repeats 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
CD58 CD58 molecule
CDC25A cell division cycle 25A
CXCL8 chemokine (C-X-C motif) ligand 8
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EIF4A1 eukaryotic translation initiation factor 4A1
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GRWD1 glutamate-rich WD repeat containing 1
MRPS30 mitochondrial ribosomal protein S30
MTCL1 microtubule crosslinking factor 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
ODC1 ornithine decarboxylase 1
ORC5 origin recognition complex, subunit 5
PNO1 partner of NOB1 homolog (S. cerevisiae)
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PSPH phosphoserine phosphatase
RPP40 ribonuclease P/MRP 40kDa subunit
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
UBE2S ubiquitin-conjugating enzyme E2S
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing