BRD-K99818283_PIK-90_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K99818283_PIK-90_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CCNG2 cyclin G2
CRIP1 cysteine-rich protein 1 (intestinal)
DPP4 dipeptidyl-peptidase 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
GNAS GNAS complex locus
GRN granulin
ISG15 ISG15 ubiquitin-like modifier
KDM5D lysine (K)-specific demethylase 5D
MAOA monoamine oxidase A
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TP53I3 tumor protein p53 inducible protein 3
TPP1 tripeptidyl peptidase I
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FERMT2 fermitin family member 2
GDF15 growth differentiation factor 15
IGFBP3 insulin-like growth factor binding protein 3
NKX3-1 NK3 homeobox 1
OLFM4 olfactomedin 4
PDE4B phosphodiesterase 4B, cAMP-specific
PLTP phospholipid transfer protein
RGS2 regulator of G-protein signaling 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
TMEM45A transmembrane protein 45A
TRBC1 T cell receptor beta constant 1