BRD-K99818283_PIK-90_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K99818283_PIK-90_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
ARMT1 acidic residue methyltransferase 1
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CD52 CD52 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
EDN1 endothelin 1
FOXO4 forkhead box O4
GUSB glucuronidase, beta
HBP1 HMG-box transcription factor 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ITGA6 integrin, alpha 6
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
MBNL2 muscleblind-like splicing regulator 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
N4BP2L1 NEDD4 binding protein 2-like 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RB1CC1 RB1-inducible coiled-coil 1
RHOB ras homolog family member B
S100A9 S100 calcium binding protein A9
SLC35E2B solute carrier family 35, member E2B
SMAD3 SMAD family member 3
SYNJ2 synaptojanin 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGIF1 TGFB-induced factor homeobox 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRBC1 T cell receptor beta constant 1
TST thiosulfate sulfurtransferase (rhodanese)
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
AFP alpha-fetoprotein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EXOSC4 exosome component 4
GPC3 glypican 3
GSPT1 G1 to S phase transition 1
HSPA8 heat shock 70kDa protein 8
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PAX8 paired box 8
PLK2 polo-like kinase 2
PNP purine nucleoside phosphorylase
SCG2 secretogranin II
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SRSF6 serine/arginine-rich splicing factor 6
TFRC transferrin receptor
TMEM100 transmembrane protein 100
TNPO1 transportin 1