BRD-K99818283_PIK-90_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

112 genes differentially expressed following the BRD-K99818283_PIK-90_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPN asporin
C10ORF10 chromosome 10 open reading frame 10
C1ORF115 chromosome 1 open reading frame 115
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD93 CD93 molecule
CD99 CD99 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL10A1 collagen, type X, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRISP3 cysteine-rich secretory protein 3
CTSK cathepsin K
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP4 fatty acid binding protein 4, adipocyte
FBLN1 fibulin 1
FILIP1L filamin A interacting protein 1-like
FOXO4 forkhead box O4
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
GSAP gamma-secretase activating protein
HOPX HOP homeobox
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
KDM5D lysine (K)-specific demethylase 5D
KRT18 keratin 18, type I
LIMCH1 LIM and calponin homology domains 1
LOC100272216 uncharacterized LOC100272216
MGP matrix Gla protein
MMP11 matrix metallopeptidase 11
MMP2 matrix metallopeptidase 2
MPDZ multiple PDZ domain protein
MYH11 myosin, heavy chain 11, smooth muscle
MYO6 myosin VI
NOX4 NADPH oxidase 4
NUAK1 NUAK family, SNF1-like kinase, 1
PAWR PRKC, apoptosis, WT1, regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLN phospholamban
PLSCR4 phospholipid scramblase 4
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC35E2B solute carrier family 35, member E2B
SP110 SP110 nuclear body protein
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SULF1 sulfatase 1
THBS1 thrombospondin 1
TM7SF2 transmembrane 7 superfamily member 2
TPP1 tripeptidyl peptidase I
TRAPPC6A trafficking protein particle complex 6A
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
AK4 adenylate kinase 4
BOP1 block of proliferation 1
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CD58 CD58 molecule
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
EIF5 eukaryotic translation initiation factor 5
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM162A family with sequence similarity 162, member A
FASTKD5 FAST kinase domains 5
FKBP14 FK506 binding protein 14, 22 kDa
GPM6B glycoprotein M6B
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HILPDA hypoxia inducible lipid droplet-associated
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOMER2 homer scaffolding protein 2
HOXB6 homeobox B6
IGFBP3 insulin-like growth factor binding protein 3
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KLK6 kallikrein-related peptidase 6
LOC100505650 uncharacterized LOC100505650
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NOP16 NOP16 nucleolar protein
PAX8 paired box 8
PDIA6 protein disulfide isomerase family A, member 6
PFN2 profilin 2
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PLIN2 perilipin 2
PTN pleiotrophin
PTX3 pentraxin 3, long
PUF60 poly-U binding splicing factor 60KDa
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SPAG4 sperm associated antigen 4
TMEM176A transmembrane protein 176A
UCK2 uridine-cytidine kinase 2