BRD-K99818283_PIK-90_AGS_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

137 genes differentially expressed following the BRD-K99818283_PIK-90_AGS_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD36B ankyrin repeat domain 36B
ASS1 argininosuccinate synthase 1
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
BPHL biphenyl hydrolase-like (serine hydrolase)
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CD9 CD9 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COLEC12 collectin sub-family member 12
CPT1A carnitine palmitoyltransferase 1A (liver)
CXADR coxsackie virus and adenovirus receptor
DENND1B DENN/MADD domain containing 1B
EFNA1 ephrin-A1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FN1 fibronectin 1
GNAS GNAS complex locus
GRB7 growth factor receptor-bound protein 7
GSDMB gasdermin B
HBP1 HMG-box transcription factor 1
HIST1H4C histone cluster 1, H4c
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNMT histamine N-methyltransferase
IFI27 interferon, alpha-inducible protein 27
IGL immunoglobulin lambda locus
IPO13 importin 13
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLHL24 kelch-like family member 24
LTB lymphotoxin beta (TNF superfamily, member 3)
LXN latexin
MAMLD1 mastermind-like domain containing 1
MCOLN1 mucolipin 1
NDRG1 N-myc downstream regulated 1
NONO non-POU domain containing, octamer-binding
NPIPB3 nuclear pore complex interacting protein family, member B3
PDE4B phosphodiesterase 4B, cAMP-specific
POSTN periostin, osteoblast specific factor
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRAME preferentially expressed antigen in melanoma
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RAD21 RAD21 homolog (S. pombe)
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN2 reticulon 2
SATB1 SATB homeobox 1
SLC38A2 solute carrier family 38, member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
STON1 stonin 1
TKTL1 transketolase-like 1
TLN1 talin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
AMD1 adenosylmethionine decarboxylase 1
ANXA6 annexin A6
ARG1 arginase 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
C20ORF24 chromosome 20 open reading frame 24
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLEC11A C-type lectin domain family 11, member A
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DBF4 DBF4 zinc finger
DCTD dCMP deaminase
DHCR7 7-dehydrocholesterol reductase
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4E eukaryotic translation initiation factor 4E
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM216A family with sequence similarity 216, member A
FAM98A family with sequence similarity 98, member A
FASN fatty acid synthase
GRWD1 glutamate-rich WD repeat containing 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA14 heat shock 70kDa protein 14
HSPB8 heat shock 22kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
IPO5 importin 5
KLF4 Kruppel-like factor 4 (gut)
LAT2 linker for activation of T cells family, member 2
LIPG lipase, endothelial
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTF lactotransferrin
MAP2K3 mitogen-activated protein kinase kinase 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
OLFML3 olfactomedin-like 3
PI3 peptidase inhibitor 3, skin-derived
PLK2 polo-like kinase 2
PLSCR3 phospholipid scramblase 3
PNP purine nucleoside phosphorylase
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RCAN1 regulator of calcineurin 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A12 S100 calcium binding protein A12
S100A6 S100 calcium binding protein A6
SACS sacsin molecular chaperone
SEPT11 septin 11
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SRM spermidine synthase
STC2 stanniocalcin 2
TARS threonyl-tRNA synthetase
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
UBE2S ubiquitin-conjugating enzyme E2S
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WDTC1 WD and tetratricopeptide repeats 1
ZNF593 zinc finger protein 593