BRD-K99545815_PF-562271_LNCAP_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K99545815_PF-562271_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE2 adhesion G protein-coupled receptor E2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APLP2 amyloid beta (A4) precursor-like protein 2
AREG amphiregulin
BCL2A1 BCL2-related protein A1
BTBD3 BTB (POZ) domain containing 3
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CGA glycoprotein hormones, alpha polypeptide
DSTN destrin (actin depolymerizing factor)
EPCAM epithelial cell adhesion molecule
FAM46A family with sequence similarity 46, member A
FASTKD5 FAST kinase domains 5
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXF1 forkhead box F1
GAL galanin/GMAP prepropeptide
GPATCH8 G patch domain containing 8
GRN granulin
GSTA1 glutathione S-transferase alpha 1
HBB hemoglobin, beta
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LYN LYN proto-oncogene, Src family tyrosine kinase
MN1 meningioma (disrupted in balanced translocation) 1
NFIL3 nuclear factor, interleukin 3 regulated
NPTX2 neuronal pentraxin II
PAM peptidylglycine alpha-amidating monooxygenase
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRDX2 peroxiredoxin 2
RBBP7 retinoblastoma binding protein 7
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SQRDL sulfide quinone reductase-like (yeast)
STOM stomatin
TICAM1 toll-like receptor adaptor molecule 1
TMEM30B transmembrane protein 30B
UPK1B uroplakin 1B
VCAN versican

decreased expression

Symbol Name
ARMCX1 armadillo repeat containing, X-linked 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
C6ORF62 chromosome 6 open reading frame 62
CCNF cyclin F
CTGF connective tissue growth factor
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF5 eukaryotic translation initiation factor 5
EVI2A ecotropic viral integration site 2A
FAM111A family with sequence similarity 111, member A
GIMAP4 GTPase, IMAP family member 4
GIMAP6 GTPase, IMAP family member 6
GOLGA8A golgin A8 family, member A
HNMT histamine N-methyltransferase
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IRS1 insulin receptor substrate 1
LIMCH1 LIM and calponin homology domains 1
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NCK1 NCK adaptor protein 1
NRCAM neuronal cell adhesion molecule
PEG10 paternally expressed 10
PTX3 pentraxin 3, long
RIN2 Ras and Rab interactor 2
SATB1 SATB homeobox 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAP25 synaptosomal-associated protein, 25kDa
SRGN serglycin
SULF1 sulfatase 1
TBC1D4 TBC1 domain family, member 4
TCF4 transcription factor 4
TMEM2 transmembrane protein 2
TSPYL5 TSPY-like 5
TXNDC9 thioredoxin domain containing 9
ZIC1 Zic family member 1
ZNF217 zinc finger protein 217