BRD-K99252563_QL-XII-47_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

89 genes differentially expressed following the BRD-K99252563_QL-XII-47_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP29 Rho GTPase activating protein 29
ATF3 activating transcription factor 3
C10ORF10 chromosome 10 open reading frame 10
CCNL1 cyclin L1
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
CYTH1 cytohesin 1
DST dystonin
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EDN1 endothelin 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
H2BFS H2B histone family, member S (pseudogene)
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
LIMA1 LIM domain and actin binding 1
LSR lipolysis stimulated lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAL mal, T-cell differentiation protein
MCL1 myeloid cell leukemia 1
MT1E metallothionein 1E
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR4A3 nuclear receptor subfamily 4, group A, member 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RHOB ras homolog family member B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TERF2IP telomeric repeat binding factor 2, interacting protein
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D2 TSC22 domain family, member 2
TUFT1 tuftelin 1
WEE1 WEE1 G2 checkpoint kinase
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CHPT1 choline phosphotransferase 1
COL3A1 collagen, type III, alpha 1
COX11 COX11 cytochrome c oxidase copper chaperone
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTSS cathepsin S
CXCL6 chemokine (C-X-C motif) ligand 6
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
FADS1 fatty acid desaturase 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR3 fibroblast growth factor receptor 3
HRSP12 heat-responsive protein 12
IGKV1-5 immunoglobulin kappa variable 1-5
LCN2 lipocalin 2
MALL mal, T-cell differentiation protein-like
MAP7 microtubule-associated protein 7
MAT2A methionine adenosyltransferase II, alpha
PARP1 poly (ADP-ribose) polymerase 1
PERP PERP, TP53 apoptosis effector
PODXL podocalyxin-like
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB2A1 secretoglobin, family 2A, member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SRGN serglycin
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
VCAM1 vascular cell adhesion molecule 1