BRD-K99146421_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K99146421_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADD3 adducin 3 (gamma)
BAG3 BCL2-associated athanogene 3
BCHE butyrylcholinesterase
CCNA1 cyclin A1
CLC Charcot-Leyden crystal galectin
COL11A1 collagen, type XI, alpha 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
CYTH1 cytohesin 1
EIF5 eukaryotic translation initiation factor 5
GJA1 gap junction protein, alpha 1, 43kDa
GNMT glycine N-methyltransferase
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBB hemoglobin, beta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
ITM2A integral membrane protein 2A
KYNU kynureninase
MATN2 matrilin 2
MPPED2 metallophosphoesterase domain containing 2
MT1X metallothionein 1X
PAN2 PAN2 poly(A) specific ribonuclease subunit
RND3 Rho family GTPase 3
RPS5 ribosomal protein S5
SERINC5 serine incorporator 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TPST2 tyrosylprotein sulfotransferase 2
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
UGP2 UDP-glucose pyrophosphorylase 2

decreased expression

Symbol Name
ACE2 angiotensin I converting enzyme 2
APOD apolipoprotein D
CD24 CD24 molecule
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FMO2 flavin containing monooxygenase 2 (non-functional)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
ITGA6 integrin, alpha 6
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
LTF lactotransferrin
PDZK1 PDZ domain containing 1
PKM pyruvate kinase, muscle
S100A7 S100 calcium binding protein A7
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
WFDC1 WAP four-disulfide core domain 1