BRD-K98548675_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

102 genes differentially expressed following the BRD-K98548675_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD12 ankyrin repeat domain 12
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAG3 BCL2-associated athanogene 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYBA cytochrome b-245, alpha polypeptide
DDIT4 DNA-damage-inducible transcript 4
DUSP14 dual specificity phosphatase 14
FOXO4 forkhead box O4
GOLM1 golgi membrane protein 1
GSAP gamma-secretase activating protein
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
KDM3A lysine (K)-specific demethylase 3A
KRT7 keratin 7, type II
KYNU kynureninase
LEF1 lymphoid enhancer-binding factor 1
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MCL1 myeloid cell leukemia 1
MSX1 msh homeobox 1
MT1M metallothionein 1M
NQO1 NAD(P)H dehydrogenase, quinone 1
NUPR1 nuclear protein, transcriptional regulator, 1
PDLIM5 PDZ and LIM domain 5
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRKCA protein kinase C, alpha
REEP5 receptor accessory protein 5
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNX11 sorting nexin 11
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
SQSTM1 sequestosome 1
TRAPPC3 trafficking protein particle complex 3
TXNL4B thioredoxin-like 4B
WIPF2 WAS/WASL interacting protein family, member 2
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ARMCX1 armadillo repeat containing, X-linked 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C6ORF62 chromosome 6 open reading frame 62
CCDC86 coiled-coil domain containing 86
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CIRBP cold inducible RNA binding protein
CSTA cystatin A (stefin A)
CYB5A cytochrome b5 type A (microsomal)
DCLK1 doublecortin-like kinase 1
DHCR24 24-dehydrocholesterol reductase
DUSP6 dual specificity phosphatase 6
EPCAM epithelial cell adhesion molecule
ESRP1 epithelial splicing regulatory protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL1 four and a half LIM domains 1
FXYD6 FXYD domain containing ion transport regulator 6
G0S2 G0/G1 switch 2
GLUL glutamate-ammonia ligase
GPM6B glycoprotein M6B
HES1 hes family bHLH transcription factor 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFITM1 interferon induced transmembrane protein 1
IGL immunoglobulin lambda locus
KLF5 Kruppel-like factor 5 (intestinal)
KRT19 keratin 19, type I
LRRC17 leucine rich repeat containing 17
MAT2A methionine adenosyltransferase II, alpha
MATN2 matrilin 2
MME membrane metallo-endopeptidase
MPZL2 myelin protein zero-like 2
MSMB microseminoprotein, beta-
MYO1B myosin IB
NPEPL1 aminopeptidase-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PCP4 Purkinje cell protein 4
PLAGL1 pleiomorphic adenoma gene-like 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PXDN peroxidasin
PYCARD PYD and CARD domain containing
RGS5 regulator of G-protein signaling 5
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SPARCL1 SPARC-like 1 (hevin)
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TRIM2 tripartite motif containing 2
TSPAN12 tetraspanin 12
TSPAN7 tetraspanin 7
TUBA1A tubulin, alpha 1a
UBE3C ubiquitin protein ligase E3C
ZDHHC11 zinc finger, DHHC-type containing 11