BRD-K98251413_IOX2_A375_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K98251413_IOX2_A375_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C6ORF62 chromosome 6 open reading frame 62
CCL20 chemokine (C-C motif) ligand 20
CD38 CD38 molecule
CLIC5 chloride intracellular channel 5
COLEC12 collectin sub-family member 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
ENO2 enolase 2 (gamma, neuronal)
EPHA3 EPH receptor A3
ETV5 ets variant 5
FBN1 fibrillin 1
GPM6B glycoprotein M6B
KDM3A lysine (K)-specific demethylase 3A
KLF9 Kruppel-like factor 9
LPL lipoprotein lipase
MBTPS1 membrane-bound transcription factor peptidase, site 1
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OXSR1 oxidative stress responsive 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SPAG4 sperm associated antigen 4
SPRY2 sprouty homolog 2 (Drosophila)
TPP1 tripeptidyl peptidase I
VEGFA vascular endothelial growth factor A
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
AIM1 absent in melanoma 1
AKR1C3 aldo-keto reductase family 1, member C3
AMOTL2 angiomotin like 2
ANXA1 annexin A1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASS1 argininosuccinate synthase 1
CCND2 cyclin D2
CD200 CD200 molecule
CD52 CD52 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CKLF chemokine-like factor
CSTA cystatin A (stefin A)
FXYD2 FXYD domain containing ion transport regulator 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFITM1 interferon induced transmembrane protein 1
KRT7 keratin 7, type II
LCN2 lipocalin 2
MAL mal, T-cell differentiation protein
MAP7 microtubule-associated protein 7
MPO myeloperoxidase
PDZK1 PDZ domain containing 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PROM1 prominin 1
RAB25 RAB25, member RAS oncogene family
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
SC5D sterol-C5-desaturase
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2