BRD-K98143437_SB-239063_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K98143437_SB-239063_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CCND2 cyclin D2
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
COL9A3 collagen, type IX, alpha 3
DCLK1 doublecortin-like kinase 1
DMD dystrophin
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP7 fatty acid binding protein 7, brain
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
FST follistatin
GAS2 growth arrest-specific 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
IFRD2 interferon-related developmental regulator 2
IGF1 insulin-like growth factor 1 (somatomedin C)
INHBB inhibin, beta B
KLK5 kallikrein-related peptidase 5
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PECR peroxisomal trans-2-enoyl-CoA reductase
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PON3 paraoxonase 3
RAB4A RAB4A, member RAS oncogene family
RPS11 ribosomal protein S11
SORBS1 sorbin and SH3 domain containing 1
SORBS3 sorbin and SH3 domain containing 3
SRPX sushi-repeat containing protein, X-linked
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TRAK2 trafficking protein, kinesin binding 2
VDAC1 voltage-dependent anion channel 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BHLHE41 basic helix-loop-helix family, member e41
CBR3 carbonyl reductase 3
CCL5 chemokine (C-C motif) ligand 5
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL10A1 collagen, type X, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EVI2B ecotropic viral integration site 2B
GAS1 growth arrest-specific 1
GDF15 growth differentiation factor 15
GOLGA8A golgin A8 family, member A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HNMT histamine N-methyltransferase
HOXB7 homeobox B7
IFNGR1 interferon gamma receptor 1
IGL immunoglobulin lambda locus
INSR insulin receptor
ITFG1 integrin alpha FG-GAP repeat containing 1
JCHAIN joining chain of multimeric IgA and IgM
KRT17 keratin 17, type I
KRT18 keratin 18, type I
LIMCH1 LIM and calponin homology domains 1
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PENK proenkephalin
S100A9 S100 calcium binding protein A9
SOD2 superoxide dismutase 2, mitochondrial
SOX11 SRY (sex determining region Y)-box 11
SULF1 sulfatase 1
TGM2 transglutaminase 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
WNT5A wingless-type MMTV integration site family, member 5A