BRD-K97810537_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K97810537_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ADAM10 ADAM metallopeptidase domain 10
AK4 adenylate kinase 4
ALCAM activated leukocyte cell adhesion molecule
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
C3ORF14 chromosome 3 open reading frame 14
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPD carboxypeptidase D
DCN decorin
DHCR24 24-dehydrocholesterol reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
FABP7 fatty acid binding protein 7, brain
FGG fibrinogen gamma chain
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFRD2 interferon-related developmental regulator 2
IPW imprinted in Prader-Willi syndrome (non-protein coding)
LUM lumican
LYPD1 LY6/PLAUR domain containing 1
MYBPC1 myosin binding protein C, slow type
MYOZ2 myozenin 2
NEB nebulin
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSDHL NAD(P) dependent steroid dehydrogenase-like
ORM1 orosomucoid 1
PLS3 plastin 3
STIP1 stress-induced phosphoprotein 1
TXNDC9 thioredoxin domain containing 9
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
BLNK B-cell linker
BRD2 bromodomain containing 2
C2CD2 C2 calcium-dependent domain containing 2
CRISP3 cysteine-rich secretory protein 3
CTPS1 CTP synthase 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEGS1 delta(4)-desaturase, sphingolipid 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GATA3 GATA binding protein 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXC6 homeobox C6
HSPA2 heat shock 70kDa protein 2
HSPB8 heat shock 22kDa protein 8
IPO13 importin 13
LITAF lipopolysaccharide-induced TNF factor
MFAP5 microfibrillar associated protein 5
MLF1 myeloid leukemia factor 1
MX1 MX dynamin-like GTPase 1
NDRG2 NDRG family member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS10 regulator of G-protein signaling 10
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SNX11 sorting nexin 11
TOB1 transducer of ERBB2, 1
TSPAN1 tetraspanin 1
TXNIP thioredoxin interacting protein
UBE2G2 ubiquitin-conjugating enzyme E2G 2
ZNF586 zinc finger protein 586