BRD-K97764662_PD-173074_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K97764662_PD-173074_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANXA1 annexin A1
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
C1QTNF3 C1q and tumor necrosis factor related protein 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CECR1 cat eye syndrome chromosome region, candidate 1
COL8A2 collagen, type VIII, alpha 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EHD3 EH-domain containing 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LAMP5 lysosomal-associated membrane protein family, member 5
MAP1B microtubule-associated protein 1B
MAP2K6 mitogen-activated protein kinase kinase 6
NELL2 NEL-like 2 (chicken)
OLFML3 olfactomedin-like 3
PHGDH phosphoglycerate dehydrogenase
PLXNC1 plexin C1
PTN pleiotrophin
QDPR quinoid dihydropteridine reductase
QPRT quinolinate phosphoribosyltransferase
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPL39L ribosomal protein L39-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TPD52L1 tumor protein D52-like 1
TSPYL5 TSPY-like 5
VAT1 vesicle amine transport 1
VIM vimentin
ZNF586 zinc finger protein 586
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADORA2B adenosine A2b receptor
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CAV1 caveolin 1, caveolae protein, 22kDa
CCL20 chemokine (C-C motif) ligand 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHMP4A charged multivesicular body protein 4A
CPM carboxypeptidase M
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
FABP4 fatty acid binding protein 4, adipocyte
FAM46A family with sequence similarity 46, member A
FXYD3 FXYD domain containing ion transport regulator 3
HCAR3 hydroxycarboxylic acid receptor 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JCHAIN joining chain of multimeric IgA and IgM
KRT17 keratin 17, type I
LAMA3 laminin, alpha 3
LGALS3 lectin, galactoside-binding, soluble, 3
LUM lumican
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MARCO macrophage receptor with collagenous structure
MGP matrix Gla protein
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PXMP2 peroxisomal membrane protein 2, 22kDa
RND3 Rho family GTPase 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
TOP2A topoisomerase (DNA) II alpha 170kDa
TPSAB1 tryptase alpha/beta 1
TSPAN4 tetraspanin 4