BRD-K97274161_N-{2-[benzyl(isopropyl)amino]ethyl}-4-({[(4-methylphenyl)sulfonyl]amino}methyl)benzamide_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K97274161_N-{2-[benzyl(isopropyl)amino]ethyl}-4-({[(4-methylphenyl)sulfonyl]amino}methyl)benzamide_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CD44 CD44 molecule (Indian blood group)
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
DKK3 dickkopf WNT signaling pathway inhibitor 3
FRY furry homolog (Drosophila)
GPNMB glycoprotein (transmembrane) nmb
H2AFV H2A histone family, member V
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IGKC immunoglobulin kappa constant
LMO3 LIM domain only 3 (rhombotin-like 2)
LTBP2 latent transforming growth factor beta binding protein 2
MDK midkine (neurite growth-promoting factor 2)
MMP1 matrix metallopeptidase 1
MPO myeloperoxidase
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SFRP4 secreted frizzled-related protein 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
SULF1 sulfatase 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNS3 tensin 3
TRIM2 tripartite motif containing 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
WFDC2 WAP four-disulfide core domain 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP7 A kinase (PRKA) anchor protein 7
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BMI1 BMI1 proto-oncogene, polycomb ring finger
CHSY1 chondroitin sulfate synthase 1
CTTN cortactin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EAPP E2F-associated phosphoprotein
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HSPB8 heat shock 22kDa protein 8
KRT17 keratin 17, type I
LYPLA1 lysophospholipase I
PLK2 polo-like kinase 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RBM47 RNA binding motif protein 47
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
UBE2A ubiquitin-conjugating enzyme E2A