BRD-K97056771_HY-11007_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K97056771_HY-11007_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
AKAP12 A kinase (PRKA) anchor protein 12
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CA2 carbonic anhydrase II
CAV1 caveolin 1, caveolae protein, 22kDa
CD9 CD9 molecule
CD99 CD99 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CREB1 cAMP responsive element binding protein 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GDF15 growth differentiation factor 15
HSPH1 heat shock 105kDa/110kDa protein 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ITGA6 integrin, alpha 6
KRT7 keratin 7, type II
MFAP5 microfibrillar associated protein 5
MME membrane metallo-endopeptidase
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
ODC1 ornithine decarboxylase 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPAP2B phosphatidic acid phosphatase type 2B
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SPARCL1 SPARC-like 1 (hevin)
STOM stomatin
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADD3 adducin 3 (gamma)
AKAP7 A kinase (PRKA) anchor protein 7
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BEX1 brain expressed, X-linked 1
BTG1 B-cell translocation gene 1, anti-proliferative
C2CD5 C2 calcium-dependent domain containing 5
CHRDL1 chordin-like 1
CLU clusterin
CTTN cortactin
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DEFB1 defensin, beta 1
DOK4 docking protein 4
DPYSL3 dihydropyrimidinase-like 3
EMP2 epithelial membrane protein 2
FLT3 fms-related tyrosine kinase 3
FOXN3 forkhead box N3
FZD7 frizzled class receptor 7
GSTA1 glutathione S-transferase alpha 1
GSTM3 glutathione S-transferase mu 3 (brain)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA5 homeobox A5
HSPA2 heat shock 70kDa protein 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IRS2 insulin receptor substrate 2
LDOC1 leucine zipper, down-regulated in cancer 1
LY75 lymphocyte antigen 75
LYPD1 LY6/PLAUR domain containing 1
LYZ lysozyme
MEIS1 Meis homeobox 1
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NEFL neurofilament, light polypeptide
NTS neurotensin
PCP4 Purkinje cell protein 4
PEG10 paternally expressed 10
PROM1 prominin 1
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTN pleiotrophin
RBPMS RNA binding protein with multiple splicing
RPL27A ribosomal protein L27a
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
TFEC transcription factor EC
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC2 tuberous sclerosis 2
TYRP1 tyrosinase-related protein 1